Bidirectional cross talk between patient-derived melanoma and cancer-associated fibroblasts promotes invasion and proliferation

Pigment Cell and Melanoma Research

Volumn 29, Issue 6, 2016, Pages 656-668

  Izar, Benjamin ^a,b,c   Joyce, Cailin E ^b,c   Goff, Stephanie ^a,e   Cho, Nancy L ^a   Shah, Parin M ^b,c   Sharma, Gaurav ^a   Li, Jingjing ^c   Ibrahim, Nageatte ^c,f   Gold, Jason ^d   Hodi, F Stephen ^c   Garraway, Levi A ^b,c   Novina, Carl D ^b,c   Bertagnolli, Monica M ^a   Yoon, Charles H ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

^d Surgical Service 112   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

^f MERCK RESEARCH LABORATORIES   (United States)

Author keywords

CAFs; melanoma; metastasis; TGF EGFR; tumor stroma

Indexed keywords

AFATINIB; CD45 ANTIGEN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH DIFFERENTIATION FACTOR 15; PLATELET DERIVED GROWTH FACTOR AA; TRANSFORMING GROWTH FACTOR ALPHA;

A375 CELL LINE; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER ASSOCIATED FIBROBLAST; CANCER GROWTH; CELL INVASION; CELL PROLIFERATION; CLINICAL ARTICLE; COCULTURE; CONDITIONED MEDIUM; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MELANOMA CELL; MELANOMA METASTASIS; METASTASIS POTENTIAL; METASTATIC MELANOMA; MIXED CELL CULTURE; MONOCULTURE; RNA SEQUENCE; TUMOR INVASION; CELL MOTION; MELANOMA; METABOLISM; PATHOLOGY; STROMA CELL; TUMOR CELL CULTURE;

CANCER-ASSOCIATED FIBROBLASTS; CELL MOVEMENT; CELL PROLIFERATION; COCULTURE TECHNIQUES; CULTURE MEDIA, CONDITIONED; EPITHELIAL-MESENCHYMAL TRANSITION; HUMANS; MELANOMA; NEOPLASM INVASIVENESS; STROMAL CELLS; TUMOR CELLS, CULTURED;

EID: 84988624490     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/pcmr.12513     Document Type: Article

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