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Volumn 10, Issue 5, 2008, Pages 439-446

Melanoma and the tumor microenvironment

Author keywords

[No Author keywords available]

Indexed keywords

AFLIBERCEPT; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; AXITINIB; B RAF KINASE; BATIMASTAT; BEVACIZUMAB; CEDIRANIB; CHIR 265; CILENGITIDE; CNTO 95; GC 1008; INCYCLINIDE; MARIMASTAT; MATRIX METALLOPROTEINASE INHIBITOR; MONOCLONAL ANTIBODY LM 609; N ACETYLSARCOSYLGLYCYLVALYL DEXTRO ALLOISOLEUCYLTHREONYLNORVALYLISOLEUCYLARGINYLPROLINE ETHYLAMIDE; ROMIDEPSIN; SORAFENIB; SUNITINIB; UNCLASSIFIED DRUG; UROKINASE; VOLOCIXIMAB; VORINOSTAT; MATRIX METALLOPROTEINASE;

EID: 55749112156     PISSN: 15233790     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11912-008-0067-y     Document Type: Review
Times cited : (166)

References (50)
  • 1
    • 36849030243 scopus 로고    scopus 로고
    • Management of metastatic melanoma
    • Tawbi HA, Kirkwood JM: Management of metastatic melanoma. Semin Oncol 2007, 34:532-545.
    • (2007) Semin Oncol , vol.34 , pp. 532-545
    • Tawbi, H.A.1    Kirkwood, J.M.2
  • 2
    • 38849182724 scopus 로고    scopus 로고
    • In vitro three-dimensional tumor microenvironment models for anticancer drug discovery
    • Smalley KS, Lioni M, Noma K, et al.: In vitro three-dimensional tumor microenvironment models for anticancer drug discovery. Expert Opin Drug Discov 2008, 3:1-10.
    • (2008) Expert Opin Drug Discov , vol.3 , pp. 1-10
    • Smalley, K.S.1    Lioni, M.2    Noma, K.3
  • 3
    • 19544362066 scopus 로고    scopus 로고
    • Adhesion, migration and communication in melanocytes and melanoma
    • Haass NK, Smalley KS, Li L, et al.: Adhesion, migration and communication in melanocytes and melanoma. Pigment Cell Res 2005, 18:150-159.
    • (2005) Pigment Cell Res , vol.18 , pp. 150-159
    • Haass, N.K.1    Smalley, K.S.2    Li, L.3
  • 4
    • 21344456180 scopus 로고    scopus 로고
    • The RAS/RAF/MEK/ERK and PI3K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma
    • Meier F, Schittek B, Busch S, et al.: The RAS/RAF/MEK/ERK and PI3K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma. Front Biosci 2005, 10:2986-3001.
    • (2005) Front Biosci , vol.10 , pp. 2986-3001
    • Meier, F.1    Schittek, B.2    Busch, S.3
  • 5
    • 2942612844 scopus 로고    scopus 로고
    • Reversal of melanocytic malignancy by keratinocytes is an E-cadherin-mediated process overriding beta-catenin signaling
    • Li G, Fukunaga M, Herlyn M: Reversal of melanocytic malignancy by keratinocytes is an E-cadherin-mediated process overriding beta-catenin signaling. Exp Cell Res 2004, 297:142-151.
    • (2004) Exp Cell Res , vol.297 , pp. 142-151
    • Li, G.1    Fukunaga, M.2    Herlyn, M.3
  • 6
    • 0036993573 scopus 로고    scopus 로고
    • Melanoma development and progression: A conspiracy between tumor and host
    • Hsu MY, Meier F, Herlyn M: MelanAma development and progression: a conspiracy between tumor and host. Differentiation 2002, 70:522-536.
    • (2002) Differentiation , vol.70 , pp. 522-536
    • Hsu, M.Y.1    Meier, F.2    Herlyn, M.3
  • 7
    • 0035947772 scopus 로고    scopus 로고
    • E-cadherin suppresses cellular transformation by inhibiting beta-catenin signaling in an adhesion-independent manner
    • Gottardi CJ, Wong E, Gumbiner BM: E-cadherin suppresses cellular transformation by inhibiting beta-catenin signaling in an adhesion-independent manner. J Cell Biol 2001, 153:1049-1060.
    • (2001) J Cell Biol , vol.153 , pp. 1049-1060
    • Gottardi, C.J.1    Wong, E.2    Gumbiner, B.M.3
  • 8
    • 0035328628 scopus 로고    scopus 로고
    • N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cells
    • Li G, Satyamoorthy K, Herlyn M: N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cells. Cancer Res 2001, 61:3819-3825.
    • (2001) Cancer Res , vol.61 , pp. 3819-3825
    • Li, G.1    Satyamoorthy, K.2    Herlyn, M.3
  • 9
    • 32944460267 scopus 로고    scopus 로고
    • The WNT/beta-catenin pathway in melanoma
    • Larue L, Delmas V: The WNT/beta-catenin pathway in melanoma. Front Biosci 2006, 11:733-742.
    • (2006) Front Biosci , vol.11 , pp. 733-742
    • Larue, L.1    Delmas, V.2
  • 10
    • 0037119948 scopus 로고    scopus 로고
    • Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor
    • Widlund HR, Horstmann MA, Price ER, et al.: Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor. J Cell Biol 2002, 158:1079-1087.
    • (2002) J Cell Biol , vol.158 , pp. 1079-1087
    • Widlund, H.R.1    Horstmann, M.A.2    Price, E.R.3
  • 11
    • 36249026528 scopus 로고    scopus 로고
    • Beta-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development
    • Delmas V, Beermann F, Martinozzi S, et al.: Beta-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development. Genes Dev 2007, 21:2923-2935.
    • (2007) Genes Dev , vol.21 , pp. 2923-2935
    • Delmas, V.1    Beermann, F.2    Martinozzi, S.3
  • 12
    • 0037326569 scopus 로고    scopus 로고
    • The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: A comparison with Snail and E47 repressors
    • Bolos V, Peinado H, Perez-Moreno MA, et al.: The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: A comparison with Snail and E47 repressors. J Cell Sci 2003, 116:499-511.
    • (2003) J Cell Sci , vol.116 , pp. 499-511
    • Bolos, V.1    Peinado, H.2    Perez-Moreno, M.A.3
  • 13
    • 0345599013 scopus 로고    scopus 로고
    • Autoregulation of E-cadherin expression by cadherin-cadherin interactions: The roles of beta-catenin signaling, Slug, and MAPK
    • Conacci-Sorrell M, Simcha I, Ben-Yedidia T, et al.: Autoregulation of E-cadherin expression by cadherin-cadherin interactions: The roles of beta-catenin signaling, Slug, and MAPK. J Cell Biol 2003, 163:847-857.
    • (2003) J Cell Biol , vol.163 , pp. 847-857
    • Conacci-Sorrell, M.1    Simcha, I.2    Ben-Yedidia, T.3
  • 14
    • 0035816677 scopus 로고    scopus 로고
    • Loss of E-cadherin expression in melanoma cells involves up-regulation of the transcriptional repressor Snail
    • Poser I, Dominguez D, de Herreros AG, et al.: Loss of E-cadherin expression in melanoma cells involves up-regulation of the transcriptional repressor Snail. J Biol Chem 2001, 276:24661-24666.
    • (2001) J Biol Chem , vol.276 , pp. 24661-24666
    • Poser, I.1    Dominguez, D.2    de Herreros, A.G.3
  • 15
    • 0035819040 scopus 로고    scopus 로고
    • Downregulation of E-cadherin and Desmoglein 1 by autocrine hepatocyte growth factor during melanoma development
    • Li G, Schaider H, Satyamoorthy K, et al.: Downregulation of E-cadherin and Desmoglein 1 by autocrine hepatocyte growth factor during melanoma development. Oncogene 2001, 20:8125-8135.
    • (2001) Oncogene , vol.20 , pp. 8125-8135
    • Li, G.1    Schaider, H.2    Satyamoorthy, K.3
  • 16
    • 36248987779 scopus 로고    scopus 로고
    • Osteonectin downregulates E-cadherin, induces osteopontin and focal adhesion kinase activity stimulating an invasive melanoma phenotype
    • Smit DJ, Gardiner BB, Sturm RA: Osteonectin downregulates E-cadherin, induces osteopontin and focal adhesion kinase activity stimulating an invasive melanoma phenotype. Int J Cancer 2007, 121:2653-2660.
    • (2007) Int J Cancer , vol.121 , pp. 2653-2660
    • Smit, D.J.1    Gardiner, B.B.2    Sturm, R.A.3
  • 18
    • 27544479450 scopus 로고    scopus 로고
    • Focal adhesion kinase promotes the aggressive melanoma phenotype
    • Hess AR, Postovit LM, Margaryan NV, et al.: Focal adhesion kinase promotes the aggressive melanoma phenotype. Cancer Res 2005, 65:9851-9860.
    • (2005) Cancer Res , vol.65 , pp. 9851-9860
    • Hess, A.R.1    Postovit, L.M.2    Margaryan, N.V.3
  • 19
    • 34247253325 scopus 로고    scopus 로고
    • ERK activity and G1 phase progression: Identifying dispensable versus essential activities and primary versus secondary targets
    • Villanueva J, Yung Y, Walker JL, et al.: ERK activity and G1 phase progression: Identifying dispensable versus essential activities and primary versus secondary targets. Mol Biol Cell 2007, 18:1457-1463.
    • (2007) Mol Biol Cell , vol.18 , pp. 1457-1463
    • Villanueva, J.1    Yung, Y.2    Walker, J.L.3
  • 20
    • 0036796781 scopus 로고    scopus 로고
    • Get a ligand, get a life: Integrins, signaling and cell survival
    • Stupack DG, Cheresh IA: Get a ligand, get a life: integrins, signaling and cell survival. J Cell Sci 2002, 115:3729-3738.
    • (2002) J Cell Sci , vol.115 , pp. 3729-3738
    • Stupack, D.G.1    Cheresh, D.A.2
  • 21
    • 0025012050 scopus 로고
    • Integrin distribution in malignant melanoma: Association of the beta 3 subunit with tumor progression
    • Albelda SM, Mette SA, Elder DE, et al.: Integrin distribution in malignant melanoma: Association of the beta 3 subunit with tumor progression. Cancer Res 1990, 50:6757-6764.
    • (1990) Cancer Res , vol.50 , pp. 6757-6764
    • Albelda, S.M.1    Mette, S.A.2    Elder, D.E.3
  • 22
    • 15844420283 scopus 로고    scopus 로고
    • Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3
    • Brooks PC, Stromblad S, Sanders LC, et al.: Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3. Cell 1996, 85:683-693.
    • (1996) Cell , vol.85 , pp. 683-693
    • Brooks, P.C.1    Stromblad, S.2    Sanders, L.C.3
  • 23
    • 0344731256 scopus 로고    scopus 로고
    • Integrin alpha(v)beta3 promotes M21 melanoma growth in human skin by regulating tumor cell survival
    • Petitclerc E, Stromblad S, von Schalscha TL, et al.: Integrin alpha(v)beta3 promotes M21 melanoma growth in human skin by regulating tumor cell survival. Cancer Res 1999, 59:2724-2730.
    • (1999) Cancer Res , vol.59 , pp. 2724-2730
    • Petitclerc, E.1    Stromblad, S.2    von Schalscha, T.L.3
  • 24
    • 6044278150 scopus 로고    scopus 로고
    • Shear stress modulates the interaction of platelet-secreted matrix proteins with tumor cells through the integrin alphavbeta3
    • Lawler K, Meade G, O'sullivan G, Kenny D: Shear stress modulates the interaction of platelet-secreted matrix proteins with tumor cells through the integrin alphavbeta3. Am J Physiol Cell Physiol 2004, 287:C1320-C1327.
    • (2004) Am J Physiol Cell Physiol , vol.287
    • Lawler, K.1    Meade, G.2    O'Sullivan, G.3    Kenny, D.4
  • 25
    • 0037077225 scopus 로고    scopus 로고
    • Unique ability of integrin alpha(v)beta3 to support tumor cell arrest under dynamic flow conditions
    • Pilch J, Habermann R, Felding-Habermann B: Unique ability of integrin alpha(v)beta3 to support tumor cell arrest under dynamic flow conditions. J Biol Chem 2002, 277:21930-21938.
    • (2002) J Biol Chem , vol.277 , pp. 21930-21938
    • Pilch, J.1    Habermann, R.2    Felding-Habermann, B.3
  • 26
    • 33746472334 scopus 로고    scopus 로고
    • Paxillin modulates squamous cancer cell adhesion and is important in pressure-augmented adhesion
    • Conway WC, Van der Voort van Zyp J, Thamilselvan V, et al.: Paxillin modulates squamous cancer cell adhesion and is important in pressure-augmented adhesion. J Cell Biochem 2006, 98:1507-1516.
    • (2006) J Cell Biochem , vol.98 , pp. 1507-1516
    • Conway, W.C.1    Van der Voort van Zyp, J.2    Thamilselvan, V.3
  • 27
    • 0018875604 scopus 로고
    • Role of organ selectivity in the determination of metastatic patterns of B16 melanoma
    • Hart IR, Fidler IJ: Role of organ selectivity in the determination of metastatic patterns of B16 melanoma. Cancer Res 1980, 40:2281-2287.
    • (1980) Cancer Res , vol.40 , pp. 2281-2287
    • Hart, I.R.1    Fidler, I.J.2
  • 28
    • 0036163492 scopus 로고    scopus 로고
    • Melanoma-stroma interactions: Structural and functional aspects
    • Ruiter D, Bogenrieder T, Elder D, et al.: Melanoma-stroma interactions: structural and functional aspects. Lancet Oncol 2002, 3:35-43.
    • (2002) Lancet Oncol , vol.3 , pp. 35-43
    • Ruiter, D.1    Bogenrieder, T.2    Elder, D.3
  • 30
    • 0033547426 scopus 로고    scopus 로고
    • Basic fibroblast growth factor induces a transformed phenotype in normal human melanocytes
    • Nesbit M, Nesbit HK, Bennett J, et al.: Basic fibroblast growth factor induces a transformed phenotype in normal human melanocytes. Oncogene 1999, 18:6469-6476.
    • (1999) Oncogene , vol.18 , pp. 6469-6476
    • Nesbit, M.1    Nesbit, H.K.2    Bennett, J.3
  • 31
    • 0342646934 scopus 로고    scopus 로고
    • Autocrine and paracrine regulation by cytokines and growth factors in melanoma
    • Lazar-Molnar E, Hegyesi H, Toth S, et al.: Autocrine and paracrine regulation by cytokines and growth factors in melanoma. Cytokine 2000, 12:547-554.
    • (2000) Cytokine , vol.12 , pp. 547-554
    • Lazar-Molnar, E.1    Hegyesi, H.2    Toth, S.3
  • 32
    • 0021796450 scopus 로고
    • Expression of the receptor for epidermal growth factor correlates with increased dosage of chromosome 7 in malignant melanoma
    • Koprowski H, Herlyn M, Balaban G, et al.: Expression of the receptor for epidermal growth factor correlates with increased dosage of chromosome 7 in malignant melanoma. Somat Cell Mol Genet 1985, 11:297-302.
    • (1985) Somat Cell Mol Genet , vol.11 , pp. 297-302
    • Koprowski, H.1    Herlyn, M.2    Balaban, G.3
  • 33
    • 18144365866 scopus 로고    scopus 로고
    • Role of epidermal growth factor receptor signaling in RAS-driven melanoma
    • Bardeesy N, Kim M, Xu J, et al.: Role of epidermal growth factor receptor signaling in RAS-driven melanoma. Mol Cell Biol 2005, 25:4176-4188.
    • (2005) Mol Cell Biol , vol.25 , pp. 4176-4188
    • Bardeesy, N.1    Kim, M.2    Xu, J.3
  • 34
    • 24944554507 scopus 로고    scopus 로고
    • Selective evolutionary pressure from the tissue microenvironment drives tumor progression
    • Smalley KS, Brafford PA, Herlyn M: Selective evolutionary pressure from the tissue microenvironment drives tumor progression. Semin Cancer Biol 2005, 15:451-459.
    • (2005) Semin Cancer Biol , vol.15 , pp. 451-459
    • Smalley, K.S.1    Brafford, P.A.2    Herlyn, M.3
  • 35
    • 34447258682 scopus 로고    scopus 로고
    • Microenvironmental influences in melanoma progression
    • Lee JT, Herlyn M: Microenvironmental influences in melanoma progression. J Cell Biochem 2007, 101:862-872.
    • (2007) J Cell Biochem , vol.101 , pp. 862-872
    • Lee, J.T.1    Herlyn, M.2
  • 36
    • 33745515023 scopus 로고    scopus 로고
    • Tumour microenvironment: TGFbeta: The molecular Jekyll and Hyde of cancer
    • BieTie B, Moses HL: Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer. Nat Rev Cancer 2006, 6:506-520.
    • (2006) Nat Rev Cancer , vol.6 , pp. 506-520
    • Bierie, B.1    Moses, H.L.2
  • 37
    • 20744431757 scopus 로고    scopus 로고
    • Transforming growth factor-beta and malignant melanoma: Molecular mechanisms
    • Hussein MR: Transforming growth factor-beta and malignant melanoma: molecular mechanisms. J Cutan Pathol 2005, 32:389-395.
    • (2005) J Cutan Pathol , vol.32 , pp. 389-395
    • Hussein, M.R.1
  • 38
    • 0035890359 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 increases survival of human melanoma through stroma remodeling
    • Berking C, Takemoto R, Schaider H, et al.: Transforming growth factor-beta1 increases survival of human melanoma through stroma remodeling. Cancer Res 2001, 61:8306-8316.
    • (2001) Cancer Res , vol.61 , pp. 8306-8316
    • Berking, C.1    Takemoto, R.2    Schaider, H.3
  • 39
    • 32944463899 scopus 로고    scopus 로고
    • Angiogenesis
    • Folkman J: Angiogenesis. Annu Rev Med 2006, 57:1-18.
    • (2006) Annu Rev Med , vol.57 , pp. 1-18
    • Folkman, J.1
  • 41
    • 35548982639 scopus 로고    scopus 로고
    • Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels
    • Fischer C, Jonckx B, Mazzone M, et al.: Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels. Cell 2007, 131:463-475.
    • (2007) Cell , vol.131 , pp. 463-475
    • Fischer, C.1    Jonckx, B.2    Mazzone, M.3
  • 42
    • 0035863552 scopus 로고    scopus 로고
    • Increased serum concentration of angiogenic factors in malignant melanoma patients correlates with tumor progression and survival
    • Ugurel S, Rappl G, Tilgen W, et al.: Increased serum concentration of angiogenic factors in malignant melanoma patients correlates with tumor progression and survival. J Clin Oncol 2001, 19:577-583.
    • (2001) J Clin Oncol , vol.19 , pp. 577-583
    • Ugurel, S.1    Rappl, G.2    Tilgen, W.3
  • 43
    • 0042386426 scopus 로고    scopus 로고
    • Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis
    • Hood JD, Frausto R, Kiosses WB, et al.: Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis. J Cell Biol 2003, 162:933-943.
    • (2003) J Cell Biol , vol.162 , pp. 933-943
    • Hood, J.D.1    Frausto, R.2    Kiosses, W.B.3
  • 45
    • 36148994693 scopus 로고    scopus 로고
    • The other side of MMPs: Protective roles in tumor progression
    • Martin MD, MatrisiPn LM: The other side of MMPs: protective roles in tumor progression. Cancer Metastasis Rev 2007, 26:717-724.
    • (2007) Cancer Metastasis Rev , vol.26 , pp. 717-724
    • Martin, M.D.1    Matrisian, L.M.2
  • 46
    • 33644545381 scopus 로고    scopus 로고
    • Tumour microenvironment - Opinion: Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy
    • Overall CM, Kleifeld O: TumouV microenvironment - opinion: validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy. Nat Rev Cancer 2006, 6:227-239.
    • (2006) Nat Rev Cancer , vol.6 , pp. 227-239
    • Overall, C.M.1    Kleifeld, O.2
  • 47
    • 0037207968 scopus 로고    scopus 로고
    • Randomised double blind placebo control study of adjuvant treatment with the metalloproteinase inhibitor, Marimastat in patients with inoperable colorectal hepatic metastases: Significant survival advantage in patients with musculoskeletal side-effects
    • King J, Zhao J, Clingan P, et al.: Randomised double blind placebo control study of adjuvant treatment with the metalloproteinase inhibitor, Marimastat in patients with inoperable colorectal hepatic metastases: Significant survival advantage in patients with musculoskeletal side-effects. Anticancer Res 2003, 23:639-645.
    • (2003) Anticancer Res , vol.23 , pp. 639-645
    • King, J.1    Zhao, J.2    Clingan, P.3
  • 48
    • 37549070672 scopus 로고    scopus 로고
    • Cysteine cathepsin proteases as pharmacological targets in cancer
    • Palermo C, Joyce JA: Cysteine cathepsin proteases as pharmacological targets in cancer. Trends Pharmacol Sci 2008, 29:22-28.
    • (2008) Trends Pharmacol Sci , vol.29 , pp. 22-28
    • Palermo, C.1    Joyce, J.A.2
  • 49
    • 42449100017 scopus 로고    scopus 로고
    • Tumoral and macrophage uPAR and MMP-9 contribute to the invasiveness of B16 murine melanoma cells
    • Marconi C, Bianchini F, Mannini A, et al.: Tumoral and macrophage uPAR and MMP-9 contribute to the invasiveness of B16 murine melanoma cells. Clin Exp Metastasis 2008, 23:225-231.
    • (2008) Clin Exp Metastasis , vol.23 , pp. 225-231
    • Marconi, C.1    Bianchini, F.2    Mannini, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.