Melanoma cells revive an embryonic transcriptional network to dictate phenotypic heterogeneity

Frontiers in Oncology

Volumn 4, Issue NOV, 2014, Pages

  Vandamme, Niels ^a,b   Berx, Geert ^a,b  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

Drug resistance; EMT; Melanoma; MITF; Phenotype switching; SLUG; ZEB1; ZEB2

Indexed keywords

ABC TRANSPORTER B5; FIBRONECTIN; GELATINASE A; HYPOXIA INDUCIBLE FACTOR 2ALPHA; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MONOPHENOL MONOOXYGENASE; OSTEONECTIN; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR ZEB1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UVOMORULIN;

CANCER GROWTH; CANCER STEM CELL; CELL HETEROGENEITY; CLONAL EVOLUTION; DOWN REGULATION; EMBRYO DEVELOPMENT; EPITHELIAL MESENCHYMAL TRANSITION; GENE SWITCHING; GENETIC HETEROGENEITY; HUMAN; MELANOMA; MELANOMA CELL; METASTASIS; PHENOTYPE; PHENOTYPIC PLASTICITY; PROTEIN EXPRESSION; SHORT SURVEY; TUMOR GROWTH; TUMOR MICROENVIRONMENT;

EID: 84915819303     PISSN: None     EISSN: 2234943X     Source Type: Journal    
DOI: 10.3389/fonc.2014.00352     Document Type: Short Survey

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