메뉴 건너뛰기




Volumn 8, Issue 8, 2014, Pages 1729-1746

Senescent stroma promotes prostate cancer progression: The role of miR-210

Author keywords

MiR 210; Prostate cancer; Senescence; Tumor microenvironment

Indexed keywords

BETA GALACTOSIDASE; GELATINASE A; GLUCOSE TRANSPORTER 1; HYPOXIA INDUCIBLE FACTOR 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6; INTERLEUKIN 8; KETONE BODY; LACTATE DEHYDROGENASE; LACTIC ACID; MATRIX METALLOPROTEINASE; MICRORNA 210; MONOCARBOXYLATE TRANSPORTER 4; STROMELYSIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ZEB1; TRANSCRIPTION FACTOR ZEB2; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN;

EID: 84911977766     PISSN: 15747891     EISSN: 18780261     Source Type: Journal    
DOI: 10.1016/j.molonc.2014.07.009     Document Type: Article
Times cited : (107)

References (59)
  • 2
    • 77956036249 scopus 로고    scopus 로고
    • NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFbeta1-induced fibroblast differentiation into myofibroblasts
    • Amara N., Goven D., Prost F., Muloway R., Crestani B., Boczkowski J. NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFbeta1-induced fibroblast differentiation into myofibroblasts. Thorax 2010, 65:733-738.
    • (2010) Thorax , vol.65 , pp. 733-738
    • Amara, N.1    Goven, D.2    Prost, F.3    Muloway, R.4    Crestani, B.5    Boczkowski, J.6
  • 3
    • 31544479046 scopus 로고    scopus 로고
    • The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms
    • Bavik C., Coleman I., Dean J.P., Knudsen B., Plymate S., Nelson P.S. The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms. Cancer Res. 2006, 66:794-802.
    • (2006) Cancer Res. , vol.66 , pp. 794-802
    • Bavik, C.1    Coleman, I.2    Dean, J.P.3    Knudsen, B.4    Plymate, S.5    Nelson, P.S.6
  • 6
    • 80855128461 scopus 로고    scopus 로고
    • Cellular senescence: a link between cancer and age-related degenerative disease?
    • Campisi J., Andersen J.K., Kapahi P., Melov S. Cellular senescence: a link between cancer and age-related degenerative disease?. Semin. Cancer Biol. 2011, 21:354-359.
    • (2011) Semin. Cancer Biol. , vol.21 , pp. 354-359
    • Campisi, J.1    Andersen, J.K.2    Kapahi, P.3    Melov, S.4
  • 8
    • 33746886564 scopus 로고    scopus 로고
    • Enhancement of tumor invasion depends on transdifferentiation of skin fibroblasts mediated by reactive oxygen species
    • Cat B., Stuhlmann D., Steinbrenner H., Alili L., Holtkotter O., Sies H., Brenneisen P. Enhancement of tumor invasion depends on transdifferentiation of skin fibroblasts mediated by reactive oxygen species. J.Cell Sci. 2006, 119:2727-2738.
    • (2006) J.Cell Sci. , vol.119 , pp. 2727-2738
    • Cat, B.1    Stuhlmann, D.2    Steinbrenner, H.3    Alili, L.4    Holtkotter, O.5    Sies, H.6    Brenneisen, P.7
  • 10
    • 77955170881 scopus 로고    scopus 로고
    • Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression
    • Chen Z., Li Y., Zhang H., Huang P., Luthra R. Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression. Oncogene 2010, 29:4362-4368.
    • (2010) Oncogene , vol.29 , pp. 4362-4368
    • Chen, Z.1    Li, Y.2    Zhang, H.3    Huang, P.4    Luthra, R.5
  • 11
    • 84862313154 scopus 로고    scopus 로고
    • Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression
    • Cirri P., Chiarugi P. Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression. Cancer Metastasis Rev. 2012, 31:195-208.
    • (2012) Cancer Metastasis Rev. , vol.31 , pp. 195-208
    • Cirri, P.1    Chiarugi, P.2
  • 13
    • 84864039745 scopus 로고    scopus 로고
    • Stromal fibroblasts synergize with hypoxic oxidative stress to enhance melanoma aggressiveness
    • Comito G., Giannoni E., Di Gennaro P., Segura C.P., Gerlini G., Chiarugi P. Stromal fibroblasts synergize with hypoxic oxidative stress to enhance melanoma aggressiveness. Cancer Lett. 2012, 324:31-41.
    • (2012) Cancer Lett. , vol.324 , pp. 31-41
    • Comito, G.1    Giannoni, E.2    Di Gennaro, P.3    Segura, C.P.4    Gerlini, G.5    Chiarugi, P.6
  • 14
    • 77949881221 scopus 로고    scopus 로고
    • The senescence-associated secretory phenotype: the dark side of tumor suppression
    • Coppe J.P., Desprez P.Y., Krtolica A., Campisi J. The senescence-associated secretory phenotype: the dark side of tumor suppression. Annu. Rev. Pathol. 2010, 5:99-118.
    • (2010) Annu. Rev. Pathol. , vol.5 , pp. 99-118
    • Coppe, J.P.1    Desprez, P.Y.2    Krtolica, A.3    Campisi, J.4
  • 15
    • 84891713034 scopus 로고    scopus 로고
    • Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor
    • Coppe J.P., Patil C.K., Rodier F., Sun Y., Munoz D.P., Goldstein J., Nelson P.S., Desprez P.Y., Campisi J. Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol. 2008, 6:2853-2868.
    • (2008) PLoS Biol. , vol.6 , pp. 2853-2868
    • Coppe, J.P.1    Patil, C.K.2    Rodier, F.3    Sun, Y.4    Munoz, D.P.5    Goldstein, J.6    Nelson, P.S.7    Desprez, P.Y.8    Campisi, J.9
  • 16
    • 59149091637 scopus 로고    scopus 로고
    • MicroRNA regulation of DNA repair gene expression in hypoxic stress
    • Crosby M.E., Kulshreshtha R., Ivan M., Glazer P.M. MicroRNA regulation of DNA repair gene expression in hypoxic stress. Cancer Res. 2009, 69:1221-1229.
    • (2009) Cancer Res. , vol.69 , pp. 1221-1229
    • Crosby, M.E.1    Kulshreshtha, R.2    Ivan, M.3    Glazer, P.M.4
  • 17
    • 0034626769 scopus 로고    scopus 로고
    • The age of cancer
    • DePinho R.A. The age of cancer. Nature 2000, 408:248-254.
    • (2000) Nature , vol.408 , pp. 248-254
    • DePinho, R.A.1
  • 18
    • 0027970713 scopus 로고
    • DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts
    • Di L.A., Linke S.P., Clarkin K., Wahl G.M. DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts. Genes Dev. 1994, 8:2540-2551.
    • (1994) Genes Dev. , vol.8 , pp. 2540-2551
    • Di, L.A.1    Linke, S.P.2    Clarkin, K.3    Wahl, G.M.4
  • 20
    • 84880934991 scopus 로고    scopus 로고
    • Cancer associated fibroblasts express pro-inflammatory factors in human breast and ovarian tumors
    • Erez N., Glanz S., Raz Y., Avivi C., Barshack I. Cancer associated fibroblasts express pro-inflammatory factors in human breast and ovarian tumors. Biochem. Biophys. Res. Commun. 2013, 437:397-402.
    • (2013) Biochem. Biophys. Res. Commun. , vol.437 , pp. 397-402
    • Erez, N.1    Glanz, S.2    Raz, Y.3    Avivi, C.4    Barshack, I.5
  • 21
    • 76349096670 scopus 로고    scopus 로고
    • Cancer-associated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-kappaB-dependent manner
    • Erez N., Truitt M., Olson P., Arron S.T., Hanahan D. Cancer-associated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-kappaB-dependent manner. Cancer Cell 2010, 17:135-147.
    • (2010) Cancer Cell , vol.17 , pp. 135-147
    • Erez, N.1    Truitt, M.2    Olson, P.3    Arron, S.T.4    Hanahan, D.5
  • 24
    • 0035951791 scopus 로고    scopus 로고
    • Subcytotoxic H2O2 stress triggers a release of transforming growth factor-beta 1, which induces biomarkers of cellular senescence of human diploid fibroblasts
    • Frippiat C., Chen Q.M., Zdanov S., Magalhaes J.P., Remacle J., Toussaint O. Subcytotoxic H2O2 stress triggers a release of transforming growth factor-beta 1, which induces biomarkers of cellular senescence of human diploid fibroblasts. J.Biol. Chem. 2001, 276:2531-2537.
    • (2001) J.Biol. Chem. , vol.276 , pp. 2531-2537
    • Frippiat, C.1    Chen, Q.M.2    Zdanov, S.3    Magalhaes, J.P.4    Remacle, J.5    Toussaint, O.6
  • 25
    • 79957532451 scopus 로고    scopus 로고
    • Cancer associated fibroblasts exploit reactive oxygen species through a proinflammatory signature leading to epithelial mesenchymal transition and stemness
    • Giannoni E., Bianchini F., Calorini L., Chiarugi P. Cancer associated fibroblasts exploit reactive oxygen species through a proinflammatory signature leading to epithelial mesenchymal transition and stemness. Antioxid. Redox Signal 2011, 14:2361-2371.
    • (2011) Antioxid. Redox Signal , vol.14 , pp. 2361-2371
    • Giannoni, E.1    Bianchini, F.2    Calorini, L.3    Chiarugi, P.4
  • 26
    • 77956280130 scopus 로고    scopus 로고
    • Reciprocal activation of prostate cancer cells and cancer-associated fibroblasts stimulates epithelial-mesenchymal transition and cancer stemness
    • Giannoni E., Bianchini F., Masieri L., Serni S., Torre E., Calorini L., Chiarugi P. Reciprocal activation of prostate cancer cells and cancer-associated fibroblasts stimulates epithelial-mesenchymal transition and cancer stemness. Cancer Res. 2010, 70:6945-6956.
    • (2010) Cancer Res. , vol.70 , pp. 6945-6956
    • Giannoni, E.1    Bianchini, F.2    Masieri, L.3    Serni, S.4    Torre, E.5    Calorini, L.6    Chiarugi, P.7
  • 27
    • 84859822323 scopus 로고    scopus 로고
    • EMT and oxidative stress: a bidirectional interplay affecting tumor malignancy
    • Giannoni E., Parri M., Chiarugi P. EMT and oxidative stress: a bidirectional interplay affecting tumor malignancy. Antioxid. Redox Signal 2012, 16:1248-1263.
    • (2012) Antioxid. Redox Signal , vol.16 , pp. 1248-1263
    • Giannoni, E.1    Parri, M.2    Chiarugi, P.3
  • 30
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 31
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia - a key regulatory factor in tumour growth
    • Harris A.L. Hypoxia - a key regulatory factor in tumour growth. Nat. Rev. Cancer 2002, 2:38-47.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 32
    • 50549218525 scopus 로고
    • The limited invitro lifetime of human diploid cell strains
    • Hayflick L. The limited invitro lifetime of human diploid cell strains. Exp. Cell Res. 1965, 37:614-636.
    • (1965) Exp. Cell Res. , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 34
    • 0037148342 scopus 로고    scopus 로고
    • Telomeres, aging and cancer: in search of a happy ending
    • Kim Sh S.H., Kaminker P., Campisi J. Telomeres, aging and cancer: in search of a happy ending. Oncogene 2002, 21:503-511.
    • (2002) Oncogene , vol.21 , pp. 503-511
    • Kim Sh, S.H.1    Kaminker, P.2    Campisi, J.3
  • 35
    • 79751503987 scopus 로고    scopus 로고
    • Measurement of telomere length by the Southern blot analysis of terminal restriction fragment lengths
    • Kimura M., Stone R.C., Hunt S.C., Skurnick J., Lu X., Cao X., Harley C.B., Aviv A. Measurement of telomere length by the Southern blot analysis of terminal restriction fragment lengths. Nat. Protoc. 2010, 5:1596-1607.
    • (2010) Nat. Protoc. , vol.5 , pp. 1596-1607
    • Kimura, M.1    Stone, R.C.2    Hunt, S.C.3    Skurnick, J.4    Lu, X.5    Cao, X.6    Harley, C.B.7    Aviv, A.8
  • 36
    • 0036829090 scopus 로고    scopus 로고
    • Cancer and aging: a model for the cancer promoting effects of the aging stroma
    • Krtolica A., Campisi J. Cancer and aging: a model for the cancer promoting effects of the aging stroma. Int. J. Biochem. Cell Biol. 2002, 34:1401-1414.
    • (2002) Int. J. Biochem. Cell Biol. , vol.34 , pp. 1401-1414
    • Krtolica, A.1    Campisi, J.2
  • 37
    • 0035834121 scopus 로고    scopus 로고
    • Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging
    • Krtolica A., Parrinello S., Lockett S., Desprez P.Y., Campisi J. Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:12072-12077.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 12072-12077
    • Krtolica, A.1    Parrinello, S.2    Lockett, S.3    Desprez, P.Y.4    Campisi, J.5
  • 38
  • 42
    • 0029778901 scopus 로고    scopus 로고
    • Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent
    • Ogryzko V.V., Hirai T.H., Russanova V.R., Barbie D.A., Howard B.H. Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent. Mol. Cell Biol. 1996, 16:5210-5218.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 5210-5218
    • Ogryzko, V.V.1    Hirai, T.H.2    Russanova, V.R.3    Barbie, D.A.4    Howard, B.H.5
  • 43
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • Orimo A., Gupta P.B., Sgroi D.C., Arenzana-Seisdedos F., Delaunay T., Naeem R., Carey V.J., Richardson A.L., Weinberg R.A. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 2005, 121:335-348.
    • (2005) Cell , vol.121 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3    Arenzana-Seisdedos, F.4    Delaunay, T.5    Naeem, R.6    Carey, V.J.7    Richardson, A.L.8    Weinberg, R.A.9
  • 45
    • 13944260728 scopus 로고    scopus 로고
    • Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation
    • Parrinello S., Coppe J.P., Krtolica A., Campisi J. Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation. J.Cell Sci. 2005, 118:485-496.
    • (2005) J.Cell Sci. , vol.118 , pp. 485-496
    • Parrinello, S.1    Coppe, J.P.2    Krtolica, A.3    Campisi, J.4
  • 46
    • 77952568396 scopus 로고    scopus 로고
    • Hallmarks of cancer: interactions with the tumor stroma
    • Pietras K., Ostman A. Hallmarks of cancer: interactions with the tumor stroma. Exp. Cell Res. 2010, 316:1324-1331.
    • (2010) Exp. Cell Res. , vol.316 , pp. 1324-1331
    • Pietras, K.1    Ostman, A.2
  • 48
    • 0032485213 scopus 로고    scopus 로고
    • Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts
    • Robles S.J., Adami G.R. Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts. Oncogene 1998, 16:1113-1123.
    • (1998) Oncogene , vol.16 , pp. 1113-1123
    • Robles, S.J.1    Adami, G.R.2
  • 50
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
    • Serrano M., Lin A.W., McCurrach M.E., Beach D., Lowe S.W. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 1997, 88:593-602.
    • (1997) Cell , vol.88 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 51
    • 33744988093 scopus 로고    scopus 로고
    • Sustained inhibition of oxidative phosphorylation impairs cell proliferation and induces premature senescence in human fibroblasts
    • Stockl P., Hutter E., Zwerschke W., Jansen-Durr P. Sustained inhibition of oxidative phosphorylation impairs cell proliferation and induces premature senescence in human fibroblasts. Exp. Gerontol. 2006, 41:674-682.
    • (2006) Exp. Gerontol. , vol.41 , pp. 674-682
    • Stockl, P.1    Hutter, E.2    Zwerschke, W.3    Jansen-Durr, P.4
  • 52
    • 84874603171 scopus 로고    scopus 로고
    • Cellular senescence and the senescent secretory phenotype: therapeutic opportunities
    • Tchkonia T., Zhu Y., van D.J., Campisi J., Kirkland J.L. Cellular senescence and the senescent secretory phenotype: therapeutic opportunities. J.Clin. Invest. 2013, 123:966-972.
    • (2013) J.Clin. Invest. , vol.123 , pp. 966-972
    • Tchkonia, T.1    Zhu, Y.2    van, D.J.3    Campisi, J.4    Kirkland, J.L.5
  • 53
    • 80052962390 scopus 로고    scopus 로고
    • Study on the roles of beta-catenin in hydrogen peroxide-induced senescence in human skin fibroblasts
    • Tian L.M., Xie H.F., Xiao X., Yang T., Hu Y.H., Wang W.Z., Liu L.S., Chen X., Li J. Study on the roles of beta-catenin in hydrogen peroxide-induced senescence in human skin fibroblasts. Exp. Dermatol. 2011, 20:836-838.
    • (2011) Exp. Dermatol. , vol.20 , pp. 836-838
    • Tian, L.M.1    Xie, H.F.2    Xiao, X.3    Yang, T.4    Hu, Y.H.5    Wang, W.Z.6    Liu, L.S.7    Chen, X.8    Li, J.9
  • 55
    • 78650944900 scopus 로고    scopus 로고
    • MicroRNA-210 regulates cancer cell proliferation through targeting fibroblast growth factor receptor-like 1 (FGFRL1)
    • Tsuchiya S., Fujiwara T., Sato F., Shimada Y., Tanaka E., Sakai Y., Shimizu K., Tsujimoto G. MicroRNA-210 regulates cancer cell proliferation through targeting fibroblast growth factor receptor-like 1 (FGFRL1). J.Biol. Chem. 2011, 286:420-428.
    • (2011) J.Biol. Chem. , vol.286 , pp. 420-428
    • Tsuchiya, S.1    Fujiwara, T.2    Sato, F.3    Shimada, Y.4    Tanaka, E.5    Sakai, Y.6    Shimizu, K.7    Tsujimoto, G.8
  • 56
    • 10944232632 scopus 로고    scopus 로고
    • Profiling molecular targets of TGF-beta1 in prostate fibroblast-to-myofibroblast transdifferentiation
    • Untergasser G., Gander R., Lilg C., Lepperdinger G., Plas E., Berger P. Profiling molecular targets of TGF-beta1 in prostate fibroblast-to-myofibroblast transdifferentiation. Mech. Ageing Dev. 2005, 126:59-69.
    • (2005) Mech. Ageing Dev. , vol.126 , pp. 59-69
    • Untergasser, G.1    Gander, R.2    Lilg, C.3    Lepperdinger, G.4    Plas, E.5    Berger, P.6
  • 57
    • 18144371956 scopus 로고    scopus 로고
    • Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts
    • Waghray M., Cui Z., Horowitz J.C., Subramanian I.M., Martinez F.J., Toews G.B., Thannickal V.J. Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts. FASEB J. 2005, 19:854-856.
    • (2005) FASEB J. , vol.19 , pp. 854-856
    • Waghray, M.1    Cui, Z.2    Horowitz, J.C.3    Subramanian, I.M.4    Martinez, F.J.5    Toews, G.B.6    Thannickal, V.J.7
  • 59
    • 33750798741 scopus 로고    scopus 로고
    • The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis
    • Yang G., Rosen D.G., Zhang Z., Bast R.C., Mills G.B., Colacino J.A., Mercado-Uribe I., Liu J. The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:16472-16477.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 16472-16477
    • Yang, G.1    Rosen, D.G.2    Zhang, Z.3    Bast, R.C.4    Mills, G.B.5    Colacino, J.A.6    Mercado-Uribe, I.7    Liu, J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.