In vitro prion-like behaviour of TDP-43 in ALS

Neurobiology of Disease

Volumn 96, Issue , 2016, Pages 236-247

  Smethurst, Phillip ^a   Newcombe, Jia ^a   Troakes, Claire ^b   Simone, Roberto ^a   Chen, Yun Ru ^c   Patani, Rickie ^a   Sidle, Katie ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c GENOMICS RESEARCH CENTER   (Taiwan)

Author keywords

ALS; Prion like disease; Propagation; Protein misfolding; Seeding; TDP 43

Indexed keywords

TAR DNA BINDING PROTEIN; DNA BINDING PROTEIN; GREEN FLUORESCENT PROTEIN; PRION PROTEIN; TDP-43 PROTEIN, HUMAN;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BRAIN; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DENSITOMETRY; GENETIC TRANSFECTION; HEK293 CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MORPHOLOGY; PLASMID; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PHOSPHORYLATION; SPINAL CORD; TISSUE HOMOGENATE; ANIMAL; AUTOPSY; COCULTURE; FEMALE; GENETICS; MALE; METABOLISM; MOTONEURON; MOUSE; NEUROBLASTOMA; PATHOLOGY;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; AUTOPSY; BRAIN; COCULTURE TECHNIQUES; DNA-BINDING PROTEINS; FEMALE; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; MALE; MICE; MOTOR NEURONS; NEUROBLASTOMA; PRION PROTEINS; SPINAL CORD; TRANSFECTION;

EID: 84988452880     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2016.08.007     Document Type: Article

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