The arginylation branch of the N-end rule pathway positively regulates cellular autophagic flux and clearance of proteotoxic proteins

Autophagy

Volumn 12, Issue 11, 2016, Pages 2197-2212

  Jiang, Yanxialei ^a,e   Lee, Jeeyoung ^a,b   Lee, Jung Hoon ^a,b   Lee, Joon Won ^d   Kim, Ji Hyeon ^a,b   Choi, Won Hoon ^a,b   Yoo, Young Dong ^b   Cha Molstad, Hyunjoo ^c   Kim, Bo Yeon ^c   Kwon, Yong Tae ^b   Noh, Sue Ah ^d   Kim, Kwang Pyo ^d   Lee, Min Jae ^a,b  

^a Seoul National University College of Medicine   (South Korea)

^b Seoul National University   (South Korea)

^c Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^d Kyung Hee University   (South Korea)

^e LINYI UNIVERSITY   (China)

Author keywords

ATE1; autophagy; HSPA5; N end rule pathway; neurodegenerative disease; para chloroamphetamine; ubiquitin proteasome system

Indexed keywords

AMINO ACID; ARGININE; CHLORAMPHETAMINE; DNA; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 5; HUNTINGTIN; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; MOLECULAR CHAPERONE GRP78; MOLECULAR LIBRARY; PROTEASOME; PROTEIN; PROTEIN AGGREGATE; TAU PROTEIN;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL CULTURE; CELL MATURATION; CELLULAR DISTRIBUTION; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; FEMALE; HUMAN; HUMAN CELL; ISOTOPE LABELING; LYSOSOME; MASS SPECTROMETRY; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEOMICS; ANIMAL; BIOLOGICAL MODEL; DRUG EFFECTS; FIBROBLAST; HEK293 CELL LINE; HELA CELL LINE; MEMBRANE FUSION; METABOLISM; MOLECULAR LIBRARY; MOUSE; PHARMACOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; ARGININE; AUTOPHAGOSOMES; AUTOPHAGY; BIOMARKERS; FIBROBLASTS; HEAT-SHOCK PROTEINS; HEK293 CELLS; HELA CELLS; HUMANS; HUNTINGTIN PROTEIN; ISOTOPE LABELING; LYSOSOMES; MEMBRANE FUSION; MICE; MODELS, BIOLOGICAL; P-CHLOROAMPHETAMINE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN AGGREGATES; PROTEINS; PROTEOLYSIS; PROTEOMICS; SIGNAL TRANSDUCTION; SMALL MOLECULE LIBRARIES; TAU PROTEINS;

EID: 84988310722     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2016.1222991     Document Type: Article

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