The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 27, 2012, Pages

  Piatkov, Konstantin I ^a   Brower, Christopher S ^a   Varshavsky, Alexander ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Arginylation; ATE1; Proteolysis; UBR1

Indexed keywords

ARGININE; CASPASE 3; CYSTEINE; PROAPOPTOTIC PROTEIN FRAGMENT; PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; ENZYME ACTIVATION; PRIORITY JOURNAL; PROTEIN STABILITY; SENSITIZATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINOACYLTRANSFERASES; ANIMALS; ANTIBODIES; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; ARGININE; BCL-X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; BRCA1 PROTEIN; CASPASE 3; HEK293 CELLS; HUMANS; LIM KINASES; MICE; MICE, MUTANT STRAINS; PEPTIDE FRAGMENTS; PHOSPHOPROTEINS; RABBITS; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; TNF RECEPTOR-ASSOCIATED FACTOR 1; UBIQUITIN-PROTEIN LIGASES;

MAMMALIA;

EID: 84863571174     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1207786109     Document Type: Article

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