UBR2 of the N-end rule pathway is required for chromosome stability via histone ubiquitylation in spermatocytes and somatic cells

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  An, Jee Young ^a,h   Kim, Euna ^b   Zakrzewska, Adriana ^a   Yoo, Young Dong ^b   Jang, Jun Min ^b   Han, Dong Hoon ^b   Lee, Min Jae ^c   Seo, Jai Wha ^a   Lee, Yong Jun ^d   Kim, Tae You ^b,e   de Rooij, Dirk G ^f   Kim, Bo Yeon ^g   Kwon, Yong Tae ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b Seoul National University   (South Korea)

^c Kyung Hee University   (South Korea)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^e Seoul National University   (South Korea)

^f UNIVERSITY OF AMSTERDAM   (Netherlands)

^g Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^h MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H2A; HISTONE H2B; HISTONE H3; HISTONE H4; UBIQUITIN PROTEIN LIGASE E3; UBR2 PROTEIN; UNCLASSIFIED DRUG; HISTONE; UBIQUITIN PROTEIN LIGASE; UBR2 PROTEIN, HUMAN; UBR2 PROTEIN, MOUSE;

ALLOSTERISM; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CHROMATIN; CHROMOSOMAL INSTABILITY; CONTROLLED STUDY; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; EMBRYO; HISTONE UBIQUITINATION; LUNG EXPANSION; LUNG FUNCTION; MALE; MEIOSIS; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEWBORN; NONHUMAN; PACHYTENE; PROTEIN LOCALIZATION; SOMATIC CELL; SPERMATOCYTE; ANIMAL; CONGENITAL MALFORMATION; DNA REPAIR; DRUG EFFECT; FIBROBLAST; HUMAN; LUNG ALVEOLUS; METABOLISM; PHYSIOLOGY; UBIQUITINATION;

MUS;

ANIMALS; ANIMALS, NEWBORN; CHROMATIN; CHROMOSOMAL INSTABILITY; DNA REPAIR; FIBROBLASTS; HISTONES; HUMANS; MALE; MEIOSIS; MICE; PACHYTENE STAGE; PULMONARY ALVEOLI; SPERMATOCYTES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84861214946     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0037414     Document Type: Article

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