Tcf7 is an important regulator of the switch of self-renewal and differentiation in a multipotential hematopoietic cell line

PLoS Genetics

Volumn 8, Issue 3, 2012, Pages

  Wu, Jia Qian ^a   Seay, Montrell ^b   Schulz, Vincent P ^b   Hariharan, Manoj ^a   Tuck, David ^b   Lian, Jin ^b   Du, Jiang ^c   Shi, Minyi ^a   Ye, Zhijia ^d   Gerstein, Mark ^c,e   Snyder, Michael P ^a   Weissman, Sherman ^b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Yale University   (United States)

^d THIRD MILITARY MEDICAL UNIVERSITY   (China)

^e YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; ISOPROTEIN; TCF7 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG; WNT PROTEIN; RUNX1 PROTEIN, MOUSE; SMALL INTERFERING RNA; TCF7 PROTEIN, MOUSE; TRANSCRIPTION FACTOR 7;

ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; CELL DIFFERENTIATION; CELL GROWTH; CELL MATURATION; CELL RENEWAL; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; GENE ACTIVATION; GENE EXPRESSION; GENE IDENTIFICATION; GENE REPRESSION; GENE SILENCING; GENE TARGETING; HEMATOPOIETIC STEM CELL; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; RNA SEQUENCE; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; CELL LINE; CELL PROLIFERATION; CLASSIFICATION; CYTOLOGY; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; SEQUENCE ANALYSIS;

MURINAE;

ANIMALS; ANTIGENS, CD34; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CORE BINDING FACTOR ALPHA 2 SUBUNIT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; HEMATOPOIETIC STEM CELLS; HUMANS; MICE; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RNA, SMALL INTERFERING; SEQUENCE ANALYSIS, RNA; T CELL TRANSCRIPTION FACTOR 1; TRANSCRIPTION FACTORS;

EID: 84859222400     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002565     Document Type: Article

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