Cigarette smoke extract (CSE) induces transient receptor potential ankyrin 1(TRPA1) expression via activation of HIF1αin A549 cells

Free Radical Biology and Medicine

Volumn 99, Issue , 2016, Pages 498-507

  Nie, Yichu ^a,b   Huang, Chuqin ^a   Zhong, Shan ^a   Wortley, Michael A ^b   Luo, Yulong ^a   Luo, Wei ^a   Xie, Yanqing ^a   Lai, Kefang ^a   Zhong, Nanshan ^a  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Cigarette smoke extract (CSE); Histone deacetylase 2; Hypoxia inducible factor 1 ; Nuclear factor B; Transient receptor potential ankyrin repeat 1

Indexed keywords

ANKYRIN; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CIGARETTE SMOKE CONDENSATE; HISTONE DEACETYLASE 2; HYPOXIA INDUCIBLE FACTOR 1; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PHD2 PROTEIN; PROTEIN; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; SN 50; TRANSIENT RECEPTOR POTENTIAL ANKYRIN 1; UNCLASSIFIED DRUG; BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE; EGLN1 PROTEIN, HUMAN; HDAC2 PROTEIN, HUMAN; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR PROLINE DIOXYGENASE; LEUPEPTIN; LIPOPOLYSACCHARIDE; PEPTIDE; PROTEIN BINDING; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRPA1 PROTEIN, HUMAN;

A549 CELL LINE; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DNA BINDING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; MTT ASSAY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RNA TRANSCRIPTION; WESTERN BLOTTING; A-549 CELL LINE; AGONISTS; ANALYSIS; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; DRUG MIXTURE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHARMACOLOGY; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SMOKE; TOBACCO;

A549 CELLS; COMPLEX MIXTURES; GENE EXPRESSION REGULATION; HISTONE DEACETYLASE 2; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; HYPOXIA-INDUCIBLE FACTOR-PROLINE DIOXYGENASES; I-KAPPA B PROTEINS; LEUPEPTINS; LIPOPOLYSACCHARIDES; NF-KAPPA B; PEPTIDES; PROTEIN BINDING; PROTEIN TRANSPORT; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SMOKE; TOBACCO; TRPA1 CATION CHANNEL;

EID: 84987899154     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2016.07.028     Document Type: Article

References (40)

1. [1] Rodgman, A., Smith, C.J., Perfetti, T.A., The composition of cigarette smoke: a retrospective, with emphasis on polycyclic components. Hum. Exp. Toxicol. 19 (2000), 573–595.
2. [2] Tran, I., Ji, C., Ni, I., Min, T., Tang, D., Vij, N., Role of cigarette smoke-induced aggresome gormation in chronic obstructive pulmonary disease-emphysema pathogenesis. Am. J. Respir. Cell Mol. Biol. 53 (2015), 159–173.
3. [3] Lanckacker, E.A., Tournoy, K.G., Hammad, H., Holtappels, G., Lambrecht, B.N., Joos, G.F., Maes, T., Short cigarette smoke exposure facilitates sensitisation and asthma development in mice. Eur. Respir. J. 41 (2013), 1189–1199.
4. [4] Luo, Y.L., Zhang, C.C., Li, P.B., Nie, Y.C., Wu, H., Shen, J.G., Su, W.W., Naringin attenuates enhanced cough, airway hyperresponsiveness and airway inflammation in a guinea pig model of chronic bronchitis induced by cigarette smoke. Int. Immunopharmacol. 13 (2012), 301–307.
5. [5] Nassini, R., Pedretti, P., Moretto, N., Fusi, C., Carnini, C., Facchinetti, F., Viscomi, A.R., Pisano, A.R., Stokesberry, S., Brunmark, C., Svitacheva, N., McGarvey, L., Patacchini, R., Damholt, A.B., Geppetti, P., Materazzi, S., Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation. PLoS One, 7, 2012, e42454.
6. [6] Zhong, S., Nie, Y.C., Gan, Z.Y., Liu, X.D., Fang, Z.F., Zhong, B.N., Tian, J., Huang, C.Q., Lai, K.F., Zhong, N.S., Effects of Schisandra chinensis extracts on cough and pulmonary inflammation in a cough hypersensitivity guinea pig model induced by cigarette smoke exposure. J. Ethnopharmacol. 165 (2015), 73–82.
7. [7] Abdullah, H., Heaney, L.G., Cosby, S.L., McGarvey, L.P., Rhinovirus upregulates transient receptor potential channels in a human neuronal cell line: implications for respiratory virus-induced cough reflex sensitivity. Thorax 69 (2014), 46–54.
8. [8] Buch, T.R., Schafer, E.A., Demmel, M.T., Boekhoff, I., Thiermann, H., Gudermann, T., Steinritz, D., Schmidt, A., Functional expression of the transient receptor potential channel TRPA1, a sensor for toxic lung inhalants, in pulmonary epithelial cells. Chem. Biol. Interact. 206 (2013), 462–471.
9. [9] Nassini, R., Pedretti, P., Moretto, N., Fusi, C., Carnini, C., Facchinetti, F., Viscomi, A.R., Pisano, A.R., Stokesberry, S., Brunmark, C., Svitacheva, N., McGarvey, L., Patacchini, R., Damholt, A.B., Geppetti, P., Materazzi, S., Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation. PLoS One, 7, 2012, e42454.
10. [10] Belvisi, M.G., Dubuis, E., Birrell, M.A., Transient receptor potential A1 channels: insights into cough and airway inflammatory disease. Chest 140 (2011), 1040–1047.
11. [11] Birrell, M.A., Belvisi, M.G., Grace, M., Sadofsky, L., Faruqi, S., Hele, D.J., Maher, S.A., Freund-Michel, V., Morice, A.H., TRPA1 agonists evoke coughing in guinea pig and human volunteers. Am. J. Respir. Crit. Care Med. 180 (2009), 1042–1047.
12. [12] Lin, Y.S., Hsu, C.C., Bien, M.Y., Hsu, H.C., Weng, H.T., Kou, Y.R., Activations of TRPA1 and P2X receptors are important in ROS-mediated stimulation of capsaicin-sensitive lung vagal afferents by cigarette smoke in rats. J. Appl. Physiol. 108:2010 (1985), 1293–1303.
13. [13] Simon, S.A., Liedtke, W., How irritating: the role of TRPA1 in sensing cigarette smoke and aerogenic oxidants in the airways. J. Clin. Investig. 118 (2008), 2383–2386.
14. [14] Hatano, N., Itoh, Y., Suzuki, H., Muraki, Y., Hayashi, H., Onozaki, K., Wood, I.C., Beech, D.J., Muraki, K., Hypoxia-inducible factor-1alpha (HIF1alpha) switches on transient receptor potential ankyrin repeat 1 (TRPA1) gene expression via a hypoxia response element-like motif to modulate cytokine release. J. Biol. Chem. 287 (2012), 31962–31972.
15. [15] Zhang, Q., Tang, X., Zhang, Z.F., Velikina, R., Shi, S., Le, A.D., Nicotine induces hypoxia-inducible factor-1alpha expression in human lung cancer cells via nicotinic acetylcholine receptor-mediated signaling pathways. Clin. Cancer Res. 13 (2007), 4686–4694.
16. [16] Hellermann, G.R., Nagy, S.B., Kong, X., Lockey, R.F., Mohapatra, S.S., Mechanism of cigarette smoke condensate-induced acute inflammatory response in human bronchial epithelial cells. Respir. Res., 3, 2002, 22.
17. [17] Sun, W., Chang, S.S., Fu, Y., Liu, Y., Califano, J.A., Chronic CSE treatment induces the growth of normal oral keratinocytes via PDK2 upregulation, increased glycolysis and HIF1alpha stabilization. PLoS One, 6, 2011, e16207.
18. [18] Barnes, P.J., Role of HDAC2 in the pathophysiology of COPD. Annu. Rev. Physiol. 71 (2009), 451–464.
19. [19] Wagner, T., Kiweler, N., Wolff, K., Knauer, S.K., Brandl, A., Hemmerich, P., Dannenberg, J.H., Heinzel, T., Schneider, G., Kramer, O.H., Sumoylation of HDAC2 promotes NF-kappaB-dependent gene expression. Oncotarget 6 (2015), 7123–7135.
20. [20] Hoshino, Y., Mio, T., Nagai, S., Miki, H., Ito, I., Izumi, T., Cytotoxic effects of cigarette smoke extract on an alveolar type II cell-derived cell line. Am. J. Physiol. Lung Cell Mol. Physiol. 281 (2001), L509–L516.
21. [21] Azad, G.K., Singh, V., Mandal, P., Singh, P., Golla, U., Baranwal, S., Chauhan, S., Tomar, R.S., Ebselen induces reactive oxygen species (ROS)-mediated cytotoxicity in Saccharomyces cerevisiae with inhibition of glutamate dehydrogenase being a target. FEBS Open Bio 4 (2014), 77–89.
22. [22] Wu, Y.L., Lin, A.H., Chen, C.H., Huang, W.C., Wang, H.Y., Liu, M.H., Lee, T.S., Y. Ru Kou, Glucosamine attenuates cigarette smoke-induced lung inflammation by inhibiting ROS-sensitive inflammatory signaling. Free Radic. Biol. Med. 69 (2014), 208–218.
23. [23] Jaquemar, D., Schenker, T., Trueb, B., An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts. J. Biol. Chem. 274 (1999), 7325–7333.
24. [24] Mukhopadhyay, I., Gomes, P., Aranake, S., Shetty, M., Karnik, P., Damle, M., Kuruganti, S., Thorat, S., Khairatkar-Joshi, N., Expression of functional TRPA1 receptor on human lung fibroblast and epithelial cells. J. Recept. Signal Transduct. Res. 31 (2011), 350–358.
25. [25] Ramsey, I.S., Delling, M., Clapham, D.E., Clapham, An introduction to TRP channels. Annu. Rev. Physiol. 68 (2006), 619–647.
26. [26] Sun, W., Wang, Z., Cao, J., Wang, X., Han, Y., Ma, Z., Enhanced production of nitric oxide in A549 cells through activation of TRPA1 ion channel by cold stress. Nitric Oxide 40 (2014), 31–35.
27. [27] Sun, W., Wang, Z., Cao, J., Cui, H., Ma, Z., Cold stress increases reactive oxygen species formation via TRPA1 activation in A549 cells. Cell Stress Chaperones 21 (2016), 367–372.
28. [28] Naserzadeh, P., Hosseini, M.J., Mohamadzadeh, AslB., Pourahmad, J., Toxicity mechanisms of cigarette smoke on mouse fetus mitochondria. Iran. J. Pharm. Res. 14 (2015), 131–138.
29. [29] Farrall, A.L., Whitelaw, M.L., The HIF1alpha-inducible pro-cell death gene BNIP3 is a novel target of SIM2s repression through cross-talk on the hypoxia response element. Oncogene 28 (2009), 3671–3680.
30. [30] Anavi, S., Harmelin, N.B., Madar, Z., Tirosh, O., Oxidative stress impairs HIF1α activation: a novel mechanism for increased vulnerability of steatotic hepatocytes to hypoxic stress. Free Radic. Biol. Med. 52 (2012), 1531–1542.
31. [31] Jaakkola, P., Mole, D.R., Tian, Y.M., Wilson, M.I., Gielbert, J., Gaskell, S.J., von Kriegsheim, A., Hebestreit, H.F., Mukherji, M., Schofield, C.J., Maxwell, P.H., Pugh, C.W., Ratcliffe, P.J., Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 292 (2001), 468–472.
32. [32] Li, Y.N., Xi, M.M., Guo, Y., Hai, C.X., Yang, W.L., Qin, X.J., NADPH oxidase-mitochondria axis-derived ROS mediate arsenite-induced HIF-1α stabilization by inhibiting prolyl hydroxylases activity. Toxicol. Lett. 224 (2014), 165–174.
33. [33] Davidson, T.L., Chen, H., Di Toro, D.M., D'Angelo, G., Costa, M., Soluble nickel inhibits HIF-prolyl-hydroxylases creating persistent hypoxic signaling in A549 cells. Mol. Carcinog. 45 (2006), 479–489.
34. [34] Ito, K., Yamamura, S., Essilfie-Quaye, S., Cosio, B., Ito, M., Barnes, P.J., Adcock, I.M., Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression. J. Exp. Med. 203 (2006), 7–13.
35. [35] Galasinski, S.C., Resing, K.A., Goodrich, J.A., Ahn, N.G., Phosphatase inhibition leads to histone deacetylases 1 and 2 phosphorylation and disruption of corepressor interactions. J. Biol. Chem. 277 (2002), 19618–19626.
36. [36] Yoshida, T., Tuder, R.M., Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease. Physiol. Rev. 87 (2007), 1047–1082.
37. [37] Wongtrakool, C., Grooms, K., Bijli, K.M., Crothers, K., Fitzpatrick, A.M., Hart, C.M., Nicotine stimulates nerve growth factor in lung fibroblasts through an NF κB-dependent mechanism. PLoS One, 9, 2014, e109602.
38. [38] Li, Q., Zhou, X.D., Kolosov, V.P., Perelman, J.M., Nicotine reduces TNF-α expression through a α7 nAChR/MyD88/NF-ĸB pathway in HBE16 airway epithelial cells. Cell Physiol. Biochem. 27 (2011), 605–612.
39. [39] Swinson, D.E., Jones, J.L., Cox, G., Richardson, D., Harris, A.L., O'Byrne, K.J., Hypoxia-inducible factor-1 alpha in non small cell lung cancer: relation to growth factor, protease and apoptosis pathways. Int. J. Cancer 111 (2004), 43–50.
40. [40] Büch, T.R., Schäfer, E.A., Demmel, M.T., Boekhoff, I., Thiermann, H., Gudermann, T., Steinritz, D., Schmidt, A., Functional expression of the transient receptor potential channel TRPA1, a sensor for toxic lung inhalants, in pulmonary epithelial cells. Chem. Biol. Interact. 206 (2013), 462–471.