Ebselen induces reactive oxygen species (ROS)-mediated cytotoxicity in Saccharomyces cerevisiae with inhibition of glutamate dehydrogenase being a target

FEBS Open Bio

Volumn 4, Issue , 2014, Pages 77-89

  Azad, Gajendra Kumar ^a   Singh, Vikash ^a   Mandal, Papita ^a   Singh, Prabhat ^a   Golla, Upendarrao ^a   Baranwal, Shivani ^a   Chauhan, Sakshi ^a   Tomar, Raghuvir S ^a  

^a INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH BHOPAL   (India)

Author keywords

Ebselen; Glutamate dehydrogenase; Histone clipping; Mitochondrial membrane potential; ROS levels; Yeast sporulation

Indexed keywords

ACETYLCYSTEINE; CYCLOPHILIN A; CYSTEINE; EBSELEN; GLUTAMATE DEHYDROGENASE; GLUTATHIONE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HISTONE H3; PEPTIDYLPROLYL ISOMERASE; PEPTIDYLPROLYL ISOMERASE 1; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE PROGRESSION; CELL STRUCTURE; CELL SURVIVAL; CHEMICAL ANALYSIS; CONTROLLED STUDY; CYTOTOXICITY; DNA CONTENT; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE COMPLEX; FLUORESCENCE ACTIVATED CELL SORTING; GROWTH CURVE; GROWTH INHIBITION; IN VIVO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SPOROGENESIS; TWO DIMENSIONAL GEL ELECTROPHORESIS; YEAST CELL; DRUG MECHANISM; FUNGUS GROWTH; G1 PHASE CELL CYCLE CHECKPOINT; INTRACELLULAR SPACE; PROTEIN DEGRADATION; PROTEOMICS;

SACCHAROMYCES CEREVISIAE;

EID: 84892549203     PISSN: 22115463     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fob.2014.01.002     Document Type: Article

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