Genetically Encoded Biosensors Reveal PKA Hyperphosphorylation on the Myofilaments in Rabbit Heart Failure

Circulation Research

Volumn 119, Issue 8, 2016, Pages 931-943

  Barbagallo, Federica ^a,b   Xu, Bing ^a   Reddy, Gopireddy R ^a   West, Toni ^a   Wang, Qingtong ^a   Fu, Qin ^a   Li, Minghui ^a   Shi, Qian ^a   Ginsburg, Kenneth S ^a   Ferrier, William ^c,d   Isidori, Andrea M ^b   Naro, Fabio ^b   Patel, Hemal H ^e,f   Bossuyt, Julie ^a   Bers, Donald ^a   Xiang, Yang K ^g  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Department of Experimental Medicine ^*  (United States)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^f University of California   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

adrenergic receptor; heart failure; myofibrils; phosphorylation; protein kinase A

Indexed keywords

ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; CAVEOLIN 3; CYCLIC AMP DEPENDENT PROTEIN KINASE; PHOSPHODIESTERASE;

ADRENERGIC STIMULATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOSENSOR; CARDIAC MUSCLE CELL; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EXPERIMENTAL MODEL; HEART FAILURE; MUSCLE FIBRIL; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; SARCOLEMMA; ANIMAL; CELL CULTURE; ENZYMOLOGY; GENETIC PROCEDURES; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROCEDURES; RABBITS AND HARES;

ANIMALS; BIOSENSING TECHNIQUES; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; HEART FAILURE; MYOCYTES, CARDIAC; MYOFIBRILS; PHOSPHORYLATION; RABBITS;

EID: 84987654715     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.308964     Document Type: Article

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