Caveolin-3 overexpression attenuates cardiac hypertrophy via inhibition of T-type Ca2+ current modulated by protein kinase Cα in cardiomyocytes

Journal of Biological Chemistry

Volumn 290, Issue 36, 2015, Pages 22085-22100

  Markandeya, Yogananda S ^a   Phelan, Laura J ^a   Woon, Marites T ^a   Keefe, Alexis M ^a   Reynolds, Courtney R ^a   August, Benjamin K ^a   Hacker, Timothy A ^a   Roth, David M ^b,c   Patel, Hemal H ^b,c   Balijepalli, Ravi C ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^c University of California at San Diego   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD VESSELS; CALCIUM; ELECTROPHYSIOLOGY; ENZYMES; HEART; MAMMALS; PATHOLOGY; PROTEINS; SCAFFOLDS (BIOLOGY); SIGNALING; T-CELLS;

CARDIAC HYPERTROPHY; EJECTION FRACTION; NUCLEAR TRANSLOCATIONS; SCAFFOLDING PROTEINS; SIGNALING COMPLEX; SIGNALING MECHANISMS; VENTRICULAR MYOCYTES; WHOLE CELL PATCH CLAMP;

CELL SIGNALING;

ANGIOTENSIN II; ANGIOTENSIN RECEPTOR; CALCIUM CHANNEL T TYPE; CAVEOLIN 3; PROTEIN KINASE C ALPHA; SMALL INTERFERING RNA;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; CAV 3 GENE; CONTROLLED STUDY; GENE; GENE OVEREXPRESSION; HEART EJECTION FRACTION; HEART MUSCLE CELL; HEART PROTECTION; HEART VENTRICLE HYPERTROPHY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; WHOLE CELL PATCH CLAMP; ANIMAL; C57BL MOUSE; CARDIAC MUSCLE CELL; CARDIOMEGALY; CAVEOLA; CELL CULTURE; DRUG EFFECTS; GENE EXPRESSION; GENETICS; MEMBRANE POTENTIAL; METABOLISM; PATCH CLAMP TECHNIQUE; PATHOPHYSIOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE; WESTERN BLOTTING;

ANGIOTENSIN II; ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; CALCIUM CHANNELS, T-TYPE; CARDIOMEGALY; CAVEOLAE; CAVEOLIN 3; CELLS, CULTURED; GENE EXPRESSION; MALE; MEMBRANE POTENTIALS; MICE, INBRED C57BL; MICROSCOPY, ELECTRON, TRANSMISSION; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; PROTEIN KINASE C-ALPHA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

EID: 84941287108     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.674945     Document Type: Article

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