Phosphodiesterases coordinate cAMP propagation induced by two stimulatory G protein-coupled receptors in hearts

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 17, 2012, Pages 6578-6583

  Liu, Shubai ^a   Li, Ying ^b   Kim, Sungjin ^a   Fu, Qin ^a   Parikh, Dippal ^a   Sridhar, Bharat ^a   Shi, Qian ^a   Zhang, Xiaoying ^b   Guan, Yinzheng ^b   Chen, Xiongwen ^b   Xiang, Yang K ^a,c  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b TEMPLE UNIVERSITY HOSPITAL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cross talk; FRET; Subcellular diffusion

Indexed keywords

BETA ADRENERGIC RECEPTOR; CALCIUM; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; ISOPRENALINE; PHOSPHODIESTERASE IV; PHOSPHOLAMBAN; PROSTAGLANDIN E2;

ADENOVIRUS; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM SIGNALING; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME INHIBITION; HEART; HEART FAILURE; HEART MUSCLE CELL; HEART STIMULATION; INFLAMMATION; INTRACELLULAR SIGNALING; ISOLATED HEART; MOLECULAR INTERACTION; MUSCLE FIBER CONTRACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SARCOPLASMIC RETICULUM;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; CALCIUM SIGNALING; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DINOPROSTONE; ISOPROTERENOL; MICE; MYOCARDIAL CONTRACTION; MYOCARDIUM; PHOSPHORIC DIESTER HYDROLASES; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS;

EID: 84860174215     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1117862109     Document Type: Article

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