Decreasing tropomyosin phosphorylation rescues tropomyosin-induced familial hypertrophic cardiomyopathy

Journal of Biological Chemistry

Volumn 288, Issue 40, 2013, Pages 28925-28935

  Schulz, Emily M ^a   Wilder, Tanganyika ^b   Chowdhury, Shamim A K ^b   Sheikh, Hajer N ^a   Wolska, Beata M ^b,c   Solaro, R John ^b   Wieczorek, David F ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c UNIVERSITY OF ILLINOIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM;

CALCIUM UPTAKES; CARDIAC FUNCTIONS; CARDIAC REMODELING; FAMILIAL HYPERTROPHIC CARDIOMYOPATHIES; PHOSPHOLAMBAN; TROPOMYOSIN;

PHOSPHORYLATION;

ALPHA TROPOMYOSIN; PHOSPHOLAMBAN; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE 2A; UNCLASSIFIED DRUG; CALCIUM; MUTANT PROTEIN; TROPOMYOSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CARDIOVASCULAR PARAMETERS; CONTROLLED STUDY; FAMILIAL HYPERTROPHIC CARDIOMYOPATHY; FIBROSIS; GENE EXPRESSION; HEART; HEART FUNCTION; HEART MUSCLE CELL; HEART SIZE; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; TRANSGENIC MOUSE; ANIMAL; CALCIUM SIGNALING; ECHOGRAPHY; GENE EXPRESSION REGULATION; HEART FUNCTION TEST; HEART MUSCLE; IMMUNOBLOTTING; METABOLISM; MUSCLE FIBRIL; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CARDIOMYOPATHY, HYPERTROPHIC, FAMILIAL; GENE EXPRESSION REGULATION; HEART FUNCTION TESTS; IMMUNOBLOTTING; MICE; MICE, TRANSGENIC; MUTANT PROTEINS; MYOCARDIUM; MYOCYTES, CARDIAC; MYOFIBRILS; PHOSPHORYLATION; TROPOMYOSIN;

EID: 84885107602     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.466466     Document Type: Article

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