Cd47-Sirpα interaction and IL-10 constrain inflammation-induced macrophage phagocytosis of healthy self-cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 37, 2016, Pages E5434-E5443

  Bian, Zhen ^a,b   Shia, Lei ^a   Guo, Ya Lan ^a   Lv, Zhiyuan ^a   Tang, Cong ^a   Niu, Shuo ^a   Tremblay, Alexandra ^a   Venkataramani, Mahathi ^a   Culpepper, Courtney ^a   Li, Limin ^b   Zhou, Zhen ^b   Mansour, Ahmed ^a   Zhang, Yongliang ^c   Gewirtz, Andrew ^a   Kidder, Koby ^a,d   Zenb, Ke ^b   Liu, Yuan ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

^b NANJING UNIVERSITY   (China)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d RUTGERS UNIVERSITY   (United States)

Author keywords

CD47; Cytokine; Macrophage; Phagocytosis; Sirp

Indexed keywords

CALRETICULIN; CD47 ANTIGEN; FREUND ADJUVANT; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PROTEIN KINASE C; PROTEIN KINASE SYK; PROTEIN TYROSINE PHOSPHATASE SHP 1; PROTEIN TYROSINE PHOSPHATASE SHP 2; REGULATOR PROTEIN; SIGNAL REGULATORY PROTEIN ALPHA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; ZYMOSAN; CD47 PROTEIN, MOUSE; CYTOKINE; IMMUNOGLOBULIN RECEPTOR; PTPNS1 PROTEIN, MOUSE;

ADOPTIVE TRANSFER; ANEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN ANTIBODY COMPLEX; APOPTOSIS; BACTERIUM; BLOOD; CONFERENCE PAPER; CONTROLLED STUDY; DEXTRAN SODIUM SULFATE-INDUCED COLITIS; DISEASE SEVERITY; EX VIVO STUDY; FREUND ADJUVANT-INDUCED INFLAMMATION; INFLAMMATION; MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PHAGOCYTOSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SPLEEN; SPLENOMEGALY; ZYMOSAN-INDUCED PERITONITIS; ANIMAL; BIOSYNTHESIS; ENDOCYTOSIS; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY;

ANIMALS; CD47 ANTIGEN; CYTOKINES; ENDOCYTOSIS; HUMANS; INFLAMMATION; INTERLEUKIN-10; MACROPHAGES; MICE; MICE, KNOCKOUT; PHAGOCYTOSIS; PROTEIN KINASE C; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION;

EID: 84986888987     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1521069113     Document Type: Article

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