Dectin-1 uses novel mechanisms for yeast phagocytosis in macrophages

Blood

Volumn 104, Issue 13, 2004, Pages 4038-4045

  Herre, Jurgen ^b   Marshall, Andrew S J ^b   Caron, Emmanuelle ^b   Edwards, Alexander D ^b   Williams, David L ^b   Schweighoffer, Edina ^b   Tybulewicz, Victor ^b   Reis E Sousa, Caetano ^b   Gordon, Siamon ^b   Brown, Gordon D ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLUCAN; DECTIN 1; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; YEAST;

EID: 4043137282     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2004-03-1140     Document Type: Article

References (42)

1. Aderem A, Underhill DM. Mechanisms of phagocytosis in macrophages. Annu Rev Immunol. 1999;17:593-623.
2. Caron E, Hall A. Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases. Science. 1998;282:1717-1721.
3. Stahl PD, Ezekowitz RA. The mannose receptor is a pattern recognition receptor involved in host defense. Curr Opin Immunol. 1998;10:50-55.
4. Peiser L, Gough PJ, Kodama T, Gordon S. Macrophage class A scavenger receptor-mediated phagocytosis of Escherichia coli: role of cell heterogeneity, microbial strain, and culture conditions in vitro. Infect Immun. 2000;68:1953-1963.
5. Schmitter T, Agerer F, Peterson U, Munzner P, Hauck CR. Granulocyte CEACAM3 is a phagocytic receptor of the innate immune system that mediates recognition and elimination of humanspecific pathogens. J Exp Med. 2004;199:35-46.
6. Brown GD, Gordon S. Fungal beta-glucans and mammalian immunity. Immunity. 2003:19:311-315.
7. Brown GD, Gordon S. Immune recognition: a new receptor for beta-glucans. Nature. 2001:413:36-37.
8. Brown GD, Taylor PR, Reid DM, et al. Dectin-1 is a major beta-glucan receptor on macrophages. J Exp Med. 2002;196:407-412.
9. Taylor PR, Brown GD, Reid DM, et al. The beta-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages. J Immunol. 2002;169:3876-3882.
10. Ariizumi K, Shen GL, Shikano S. et al. Identification of a novel, dendritic cell-associated molecule, dectin-1, by subtractive cDNA cloning. J Biol Chem. 2000;275:20157-20167.
11. Gantner BN, Simmons RM, Canavera SJ, Akira S, Underhill DM. Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J Exp Med. 2003;197:1107-1117.
12. Brown GD, Herre J, Williams DL, Willment JA, Marshall AS, Gordon S. Dectin-1 mediates the biological effects of beta-glucans. J Exp Med. 2003;197:1119-1124.
13. Daeron M. Fc receptor biology. Annu Rev Immunol. 1997;15:203-234.
14. Crowley MT, Costello PS, Fitzer-Attas CJ, et al. A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages. J Exp Med. 1997;186:1027-1039.
15. Colucci F, Turner M, Schweighoffer E. et al. Redundant role of the Syk protein tyrosine kinase in mouse NK cell differentiation. J Immunol. 1999;163:1769-1774.
16. 2+, and adherence. J Cell Physiol. 1983;117: 189-194.
17. Taylor PR, Brown GD, Herre J, Williams DL, Willment JA, Gordon S. The role of SIGNR1 and the beta-glucan receptor (Dectin-1) in the nonopsonic recognition of yeast by specific macrophages. J Immunol. 2004;172:1157-1162.
18. Stacey M, Lin HH, Gordon S, McKnight AJ. LNB-TM7, a group of seven-transmembrane proteins related to family-B G-protein-coupled receptors. Trends Biochem Sci. 2000;25:284-289.
19. Kiefer F, Brumell J, Al-Alawi N, et al. The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophils. Mol Cell Biol. 1998;18:4209-4220.
20. Hall A. Rho GTPases and the actin cytoskeleton. Science. 1998;279:509-514.
21. Tumer M, Schweighoffer E, Colucci F, Di Santo JP, Tybulewicz VL. Tyrosine kinase SYK: essential functions for immunoreceptor signalling. Immunol Today. 2000;21:148-154.
22. Allen LH, Aderem A. A role for MARCKS, the alpha isozyme of protein kinase C and myosin I in zymosan phagocytosis by macrophages. J Exp Med. 1995;182:829-840.
23. Muelfer A, Raptis J, Rice PJ, et al. The influence of glucan polymer structure and solution conformation on binding to (1 → 3)-beta-D-glucan receptors in a human monocyte-like cell line. Glycobiology. 2000;10:339-346.
24. Strzelecka-Kiliszek A, Kwiatkowska K, Sobota A. Lyn and Syk kinases are sequentially engaged in phagocytosis mediated by Fc gamma R. J Immunol. 2002;169:6787-6794.
25. Majeed M, Caveggion E, Lowell CA, Berton G. Role of Src kinases and Syk in Fcgamma receptor-mediated phagocytosis and phagosome-lysosome fusion. J Leukoc Biol. 2001;70:801-811.
26. Garcia-Garcia E, Rosales C. Signal transduction during Fc receptor-mediated phagocytosis. J Leukoc Biol. 2002;72:1092-1108.
27. Indik ZK, Park JG, Pan XQ, Schreiber AD. Induction of phagocytosis by a protein tyrosine kinase. Blood. 1995;85:1175-1180.
28. Mitchell MA, Huang MM, Chien P, Indik ZK, Pan XQ, Schreiber AD. Substitutions and deletions in the cytoplasmic domain of the phagocytic receptor Fc gamma RIIA: effect on receptor tyrosine phosphorylation and phagocytosis. Blood. 1994; 84:1753-1759.
29. Law DA, Nannizzi-Alaimo L, Ministri K, et al. Genetic and pharmacological analyses of Syk function in alphaIIbbeta3 signaling in platelets. Blood. 1999;93:2645-2652.
30. Cox D, Dale BM, Kashiwada M, Helgason CD, Greenberg S. A regulatory role for Src homology 2 domain-containing inositol 5′-phosphatase (SHIP) in phagocytosis mediated by Fc gamma receptors and complement receptor 3 (alpha(M) beta(2); CD11b/CD18). J Exp Med. 2001;193:61-71.
31. Araki N, Johnson MT, Swanson JA. A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages. J Cell Biol. 1996;135:1249-1260.
32. Cox D, Tseng CC, Bjekic G, Greenberg S. A requirement for phosphatidylinositol 3-kinase in pseudopod extension. J Biol Chem. 1999;274:1240-1247.
33. Garcia-Garcia E, Rosales R, Rosales C. Phosphatidylinositol 3-kinase and extracellular signal-regulated kinase are recruited for Fc receptor-mediated phagocytosis during monocyte-tomacrophage differentiation. J Leukoc Biol. 2002; 72:107-114.
34. Williams DL, Li C, Ha T, et al. Modulation of the phosphoinositide 3-kinase pathway alters innate resistance to polymicrobial sepsis. J Immunol. 2004;172:449-456.
35. Allen LA, Aderem A. Molecular definition of distinct cytoskeletal structures involved in complement- and Fc receptor-mediated phagocytosis in macrophages. J Exp Med. 1996;184:627-637.
36. Carballo E, Pitterle DM, Stumpo DJ, Sperling RT, Blackshear PJ. Phagocytic and macropinocytic activity in MARCKS-deficient macrophages and fibroblasts. Am J Physiol. 1999;277:C163-173.
37. Sergeant S, McPhail LC. Opsonized zymosan stimulates the redistribution of protein kinase C isoforms in human neutrophils. J Immunol. 1997; 159:2877-2885.
38. Arbibe L, Mira JP, Teusch N, et al. Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1 -dependent pathway. Nat Immunol. 2000;1: 533-540.
39. Bonifacino JS, Dell'Angelica EC. Molecular bases for the recognition of tyrosine-based sorting signals. J Cell Biol. 1999;145:923-926.
40. Worth RG, Mayo-Bond L, Kim MK, et al. The cytoplasmic domain of FcgammaRIIA(CD32) participates in phagolysosome formation. Blood. 2001;98:3429-3434.
41. Mahnke K, Guo M, Lee S, et al. The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments. J Cell Biol. 2000;151:673-684.
42. Chimini G, Chavrier P. Function of Rho family proteins in actin dynamics during phagocytosis and engulfment. Nat Cell Biol. 2000;2:E191-196.