Inflammation-induced proteolytic processing of the SIRPα cytoplasmic ITIM in neutrophils propagates a proinflammatory state

Nature Communications

Volumn 4, Issue , 2013, Pages

  Zen, Ke ^a   Guo, Yalan ^a,b   Bian, Zhen ^a,b   Lv, Zhiyuan ^a,b   Zhu, Dihan ^a   Ohnishi, Hiroshi ^c   Matozaki, Takashi ^c   Liu, Yuan ^b  

^a NANJING UNIVERSITY   (China)

^b GEORGIA STATE UNIVERSITY   (United States)

^c GUNMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 17 ANTIBODY; REGULATOR PROTEIN; SIGNAL REGULATORY PROTEIN ALPHA; UNCLASSIFIED DRUG;

ANTIBODY; CYTOPLASM; INHIBITOR; PROTEIN; RODENT; SIGNAL;

ANIMAL MODEL; ARTICLE; CELL MIGRATION; COLITIS; CYTOPLASM; EXTRACELLULAR SPACE; GENE DELETION; GENE LOCUS; GOUT; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNORECEPTOR TYROSINE BASED INHIBITION MOTIF; IN VITRO STUDY; INFLAMMATION; INTRACELLULAR SIGNALING; MACROPHAGE; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION;

AMINO ACID MOTIFS; ANIMALS; ANTIGENS, CD47; ANTIGENS, DIFFERENTIATION; BLOTTING, WESTERN; CELL MOVEMENT; CELL SEPARATION; CYTOPLASM; DISEASE MODELS, ANIMAL; FEMALE; FLOW CYTOMETRY; GENE DELETION; HUMANS; INFLAMMATION; MICE; MICE, INBRED C57BL; NEUTROPHILS; PROTEIN BINDING; PROTEOLYSIS; RECEPTORS, IMMUNOLOGIC; SEQUENCE DELETION; SERINE PROTEASES;

EID: 84884268119     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms3436     Document Type: Article

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