Epigallocatechin-3-gallate ameliorates autoimmune arthritis by reciprocal regulation of T helper-17 regulatory T cells and inhibition of osteoclastogenesis by inhibiting STAT3 signaling

Journal of Leukocyte Biology

Volumn 100, Issue 3, 2016, Pages 559-568

  Lee, Seon Yeong ^a   Jung, Young Ok ^c   Ryu, Jun Geol ^a   Oh, Hye Jwa ^a   Son, Hye Jin ^a   Lee, Seung Hoon ^a   Kwon, Jeong Eun ^a   Kim, Eun Kyung ^a   Park, Mi Kyung ^a   Park, Sung Hwan ^a,b   Kim, Ho Youn ^a,b   Cho, Mi La ^a  

^a The Catholic University of Korea   (South Korea)

^b The Catholic University of Korea   (South Korea)

^c Hallym University   (South Korea)

Author keywords

Green tea polyphenol epigallocatechin 3 gallate (EGCG); IFN KO; Rheumatoid arthritis; Th17

Indexed keywords

CYTOKINE; EPIGALLOCATECHIN GALLATE; GA BINDING PROTEIN; GAMMA INTERFERON; HEME OXYGENASE 1; MITOGEN ACTIVATED PROTEIN KINASE; STAT3 PROTEIN; TRANSCRIPTION FACTOR FKHR; ANTIOXIDANT; CATECHIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; JOINT DESTRUCTION; LYMPHOCYTE DIFFERENTIATION; MALE; MOUSE; NONHUMAN; OSTEOCLASTOGENESIS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; SPLEEN; T LYMPHOCYTE ACTIVATION; TH17 CELL; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; ARTHRITIS, EXPERIMENTAL; AUTOIMMUNE DISEASES; BONE DEVELOPMENT; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; DBA MOUSE; DISEASE MODEL; DRUG EFFECTS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; OSTEOCLAST;

ANIMALS; ANTIOXIDANTS; ARTHRITIS, EXPERIMENTAL; AUTOIMMUNE DISEASES; CATECHIN; CELL DIFFERENTIATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; MALE; MICE; MICE, INBRED DBA; MICE, KNOCKOUT; OSTEOCLASTS; OSTEOGENESIS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; T-LYMPHOCYTES, REGULATORY; TH17 CELLS;

EID: 84985023441     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.3A0514-261RR     Document Type: Article

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