Reactive oxygen species induce expression of vascular endothelial growth factor in chondrocytes and human articular cartilage explants

Arthritis Research and Therapy

Volumn 8, Issue , 2006, Pages

  Fay, Jakob ^a   Varoga, Deike ^b   Wruck, Christoph J ^b   Kurz, Bodo ^b   Goldring, Mary B ^c,d   Pufe, Thomas ^b  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

^c HARVARD INSTITUTES OF MEDICINE   (United States)

^d HOSPITAL FOR SPECIAL SURGERY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LINSIDOMINE; NITRIC OXIDE; PHORBOL 13 ACETATE 12 MYRISTATE; REACTIVE OXYGEN METABOLITE; REAGENT; VASCULOTROPIN; VASCULOTROPIN 121; VASCULOTROPIN 165; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; ISOPROTEIN; MESSENGER RNA; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR;

ARTICLE; ARTICULAR CARTILAGE; ASPIRATION; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL IMMORTALIZATION; CLINICAL ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPLANT; GENE EXPRESSION; HUMAN; HUMAN CELL; OSTEOARTHRITIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUPERNATANT; SYNOVIAL FLUID; UPREGULATION; CELL CULTURE; CHEMISTRY; GENETICS; METABOLISM; ORGAN CULTURE TECHNIQUE;

CARTILAGE, ARTICULAR; CELLS, CULTURED; CHONDROCYTES; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMANS; ORGAN CULTURE TECHNIQUES; OSTEOARTHRITIS; PROTEIN ISOFORMS; REACTIVE OXYGEN SPECIES; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SYNOVIAL FLUID; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33846781310     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2102     Document Type: Article

References (31)

1. Fernandes JC Martel-Pelletier J Pelletier JP The role of cytokines in osteoarthritis pathophysiology Biorheology 2002 39 237-246 12082286
2. Burrage PS Mix KS Brinckerhoff CE Matrix metalloproteinases: Role in arthritis Front Biosci 2006 11 529-543 16146751
3. Ferrara N Role of vascular endothelial growth factor in the regulation of angiogenesis Kidney Int 1999 56 794-814 10.1046/ j.1523-1755.1999.00610.x 10469350
4. Neufeld G Cohen T Gengrinovitch S Poltorak Z Vascular endothelial growth factor (VEGF) and its receptors FASEB J 1999 13 9-22 9872925
5. Firestein GS Starving the synovium: Angiogenesis and inflammation in rheumatoid arthritis J Clin Invest 1999 103 3-4 407872 9884327
6. Robinson CJ Stringer SE The splice variants of vascular endothelial growth factor (VEGF) and their receptors J Cell Sci 2001 114 853-865 11181169
7. Thomas KA Vascular endothelial growth factor, a potent and selective angiogenic agent J Biol Chem 1996 271 603-606 8557658
8. Pufe T Petersen W Tillmann B Mentlein R The splice variants VEGF121 and VEGF189 of the angiogenic peptide vascular endothelial growth factor are expressed in osteoarthritic cartilage Arthritis Rheum 2001 44 1082-1088 10.1002/1529-0131(200105)44:5<1082::AID-ANR188>3.0.CO;2-X 11352239
9. Pufe T Harde V Petersen W Goldring MB Tillmann B Mentlein R Vascular endothelial growth factor (VEGF) induces matrix metalloproteinase expression in immortalized chondrocytes J Pathol 2004 202 367-374 10.1002/path.1527 14991903
10. Pfander D Kortje D Zimmermann R Weseloh G Kirsch T Gesslein M Cramer T Swoboda B Vascular endothelial growth factor in articular cartilage of healthy and osteoarthritic human knee joints Ann Rheum Dis 2001 60 1070-1073 10.1136/ard.60.11.1070 11602483
11. Enomoto H Inoki I Komiya K Shiomi T Ikeda E Obata K Matsumoto H Toyama Y Okada Y Vascular endothelial growth factor isoforms and their receptors are expressed in human osteoarthritic cartilage Am J Pathol 2003 162 171-181 12507900
12. Henrotin Y Kurz B Aigner T Oxygen and reactive oxygen species in cartilage degradation: Friends or foes? Osteoarthritis Cartilage 2005 13 643-654 10.1016/j.joca.2005.04.002 15936958
13. Rice-Evans CA Techniques in free radical research Laboratory techniques in biochemistry and molecular biology Amsterdam: Elsevier Burdon RH 1991 20
14. Henrotin YE Bruckner P Pujol JP The role of reactive oxygen species in homeostasis and degradation of cartilage Osteoarthritis Cartilage 2003 11 747-755 10.1016/S1063-4584(03)00150-X 13129694
15. Panasyuk A Frati E Ribault D Mitrovic D Effect of reactive oxygen species on the biosynthesis and structure of newly synthesized proteoglycans Free Radic Biol Med 1994 16 157-167 10.1016/ 0891-5849(94)90139-2 8005511
16. Del Carlo M Jr Loeser RF Nitric oxide-mediated chondrocyte cell death requires the generation of additional reactive oxygen species Arthritis Rheum 2002 46 394-403 10.1002/art.10056 11840442
17. Ayache N Boumediene K Mathy-Hartert M Reginster JY Henrotin Y Pujol JP Expression of TGF-betas and their receptors is differentially modulated by reactive oxygen species and nitric oxide in human articular chondrocytes Osteoarthritis Cartilage 2002 10 344-352 10.1053/ joca.2001.0499 12027535
18. Mathy-Hartert M Martin G Devel P Deby-Dupont G Pujol JP Reginster JY Henrotin Y Reactive oxygen species downregulate the expression of pro-inflammatory genes by human chondrocytes Inflamm Res 2003 52 111-118 10.1007/s000110300023 12755375
19. Li JM Mullen AM Yun S Wientjes F Brouns GY Thrasher AJ Shah AM Essential role of the NADPH oxidase subunit p47(phox) in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-alpha Circ Res 2002 90 143-150 10.1161/hh0202.103615 11834706
20. de Groot H Hegi U Sies H Loss of alpha-tocopherol upon exposure to nitric oxide or the sydnonimine SIN-1 FEBS Lett 1993 315 139-142 10.1016/ 0014-5793(93)81150-X 8417969
21. Goldring MB Birkhead JR Suen LF Yamin R Mizuno S Glowacki J Arbiser JL Apperley JF Interleukin-1 beta-modulated gene expression in immortalized human chondrocytes J Clin Invest 1994 94 2307-2316 330059 7989586
22. Muehleman C Bareither D Huch K Cole AA Kuettner KE Prevalence of degenerative morphological changes in the joints of the lower extremity Osteoarthritis Cartilage 1997 5 23-37 10.1016/S1063-4584(97)80029-5 9010876
23. Ailland J Kampen WU Schunke M Trentmann J Kurz B Beta irradiation decreases collagen type II synthesis and increases nitric oxide production and cell death in articular chondrocytes Ann Rheum Dis 2003 62 1054-1060 10.1136/ard.62.11.1054 14583567
24. Cerimele F Brown LF Bravo F Ihler GM Kouadio P Arbiser JL Infectious angiogenesis: Bartonella bacilliformis infection results in endothelial production of angiopoetin-2 and epidermal production of vascular endothelial growth factor Am J Pathol 2003 163 1321-1327 14507641
25. Gruber BL Marchese MJ Kew R Angiogenic factors stimulate mast-cell migration Blood 1995 86 2488-2493 7545457
26. De Bandt M Ben Mahdi MH Ollivier V Grossin M Dupuis M Gaudry M Bohlen P Lipson KE Rice A Wu Y Blockade of vascular endothelial growth factor receptor I (VEGF-RI), but not VEGF-RII, suppresses joint destruction in the K/BxN model of rheumatoid arthritis J Immunol 2003 171 4853-4859 14568965
27. Felson DT Lawrence RC Dieppe PA Hirsch R Helmick CG Jordan JM Kington RS Lane NE Nevitt MT Zhang Y Osteoarthritis: New insights. Part 1: the disease and its risk factors Ann Intern Med 2000 133 635-646 11033593
28. Lee EY Chung CH Kim JH Joung HJ Hong SY Antioxidants ameliorate the expression of vascular endothelial growth factor mediated by protein kinase C in diabetic podocytes Nephrol Dial Transplant 2006 21 1496-1503 10.1093/ndt/gfl022 16484238
29. Kosmidou I Xagorari A Roussos C Papapetropoulos A Reactive oxygen species stimulate VEGF production from C(2)C(12) skeletal myotubes through a PI3K/Akt pathway Am J Physiol Lung Cell Mol Physiol 2001 280 L585-L592 11237996
30. Nagashima M Yoshino S Ishiwata T Asano G Role of vascular endothelial growth factor in angiogenesis of rheumatoid arthritis J Rheumatol 1995 22 1624-1630 8523334
31. Turpaev K Litvinov D Dubovaya V Panasyuk A Ivanov D Prassolov V Induction of vascular endothelial growth factor by nitric oxide in cultured human articular chondrocytes Biochimie 2001 83 515-522 10.1016/ S0300-9084(01)01280-9 11506896