EGCG protects endothelial cells against PCB 126-induced inflammation through inhibition of AhR and induction of Nrf2-regulated genes

Toxicology and Applied Pharmacology

Volumn 261, Issue 2, 2012, Pages 181-188

  Han, Sung Gu ^a,b   Han, Seong Su ^c   Toborek, Michal ^d   Hennig, Bernhard ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Atherosclerosis; EGCG; Endothelial cell; Inflammation; PCB; Polyphenol

Indexed keywords

3,3',4,4',5 PENTACHLOROBIPHENYL; AROMATIC HYDROCARBON RECEPTOR; BIOLOGICAL MARKER; CYTOCHROME P450 1A1; EPIGALLOCATECHIN GALLATE; GLUTATHIONE TRANSFERASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (QUINONE); SUPEROXIDE; TRANSCRIPTION FACTOR NRF2; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL DAMAGE; CELL PROTECTION; CONTROLLED STUDY; DNA BINDING; DOSE RESPONSE; GENE CONTROL; HYPOTHESIS; MICROVASCULAR ENDOTHELIAL CELL; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; CATECHIN; CELLS, CULTURED; CHEMOKINE CCL2; CYTOCHROME P-450 CYP1A1; CYTOPROTECTION; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; GLUTATHIONE TRANSFERASE; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; NF-KAPPA B; OXIDATIVE STRESS; POLYCHLORINATED BIPHENYLS; RECEPTORS, ARYL HYDROCARBON; SWINE; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84861014606     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.03.024     Document Type: Article

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