-
1
-
-
0141988655
-
Anti-inflammatory actions of the heme oxygenase-1 pathway
-
DOI 10.2174/1381612033453749
-
Alcaraz MJ, Fernandez P, and Guillen MI. Anti-inflammatory actions of the heme oxygenase-1 pathway. Curr Pharm Des 9: 2541-2551, 2003. (Pubitemid 37236372)
-
(2003)
Current Pharmaceutical Design
, vol.9
, Issue.30
, pp. 2541-2551
-
-
Alcaraz, M.J.1
Fernandez, P.2
Guillen, M.I.3
-
2
-
-
77957604373
-
Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene
-
Becks L, Prince M, Burson H, Christophe C, Broadway M, Itoh K, Yamamoto M, Mathis M, Orchard E, Shi R, McLarty J, Pruitt K, Zhang S, and Kleiner-Hancock HE. Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene. BMC Cancer 10: 540, 2010.
-
(2010)
BMC Cancer
, vol.10
, pp. 540
-
-
Becks, L.1
Prince, M.2
Burson, H.3
Christophe, C.4
Broadway, M.5
Itoh, K.6
Yamamoto, M.7
Mathis, M.8
Orchard, E.9
Shi, R.10
McLarty, J.11
Pruitt, K.12
Zhang, S.13
Kleiner-Hancock, H.E.14
-
3
-
-
15044344799
-
RANK, RANKL and osteoprotegerin in arthritic bone loss
-
Bezerra MC, Carvalho JF, Prokopowitsch AS, and Pereira RM. RANK, RANKL and osteoprotegerin in arthritic bone loss. Braz J Med Biol Res 38: 161-170, 2005. (Pubitemid 40378401)
-
(2005)
Brazilian Journal of Medical and Biological Research
, vol.38
, Issue.2
, pp. 161-170
-
-
Bezerra, M.C.1
Carvalho, J.F.2
Prokopowitsch, A.S.3
Pereira, R.M.R.4
-
4
-
-
0030451213
-
NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development
-
DOI 10.1073/pnas.93.24.13943
-
Chan K, Lu R, Chang JC, and Kan YW. NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development. Proc Natl Acad Sci USA 93: 13943-13948, 1996. (Pubitemid 26424225)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.24
, pp. 13943-13948
-
-
Chan, K.1
Lu, R.2
Chang, J.C.3
Kan, Y.W.4
-
5
-
-
43949108882
-
Predominance of cyclooxygenase 1 over cyclooxygenase 2 in the generation of proinflammatory prostaglandins in autoantibody-driven K/BxN serum-transfer arthritis
-
DOI 10.1002/art.23453
-
Chen M, Boilard E, Nigrovic PA, Clark P, Xu D, FitzGerald GA, Audoly LP, and Lee DM. Predominance of cyclooxygenase 1 over cyclooxygenase 2 in the generation of proinflammatory prostaglandins in autoantibody-driven K/BxN serum-transfer arthritis. Arthritis Rheum 58: 1354-1365, 2008. (Pubitemid 351705925)
-
(2008)
Arthritis and Rheumatism
, vol.58
, Issue.5
, pp. 1354-1365
-
-
Chen, M.1
Boilard, E.2
Nigrovic, P.A.3
Clark, P.4
Xu, D.5
FitzGerald, G.A.6
Audoly, L.P.7
Lee, D.M.8
-
6
-
-
33645859047
-
Neutrophil-derived leukotriene B4 is required for inflammatory arthritis
-
Chen M, Lam BK, Kanaoka Y, Nigrovic PA, Audoly LP, Austen KF, and Lee DM. Neutrophil-derived leukotriene B4 is required for inflammatory arthritis. J Exp Med 203: 837-842, 2006.
-
(2006)
J Exp Med
, vol.203
, pp. 837-842
-
-
Chen, M.1
Lam, B.K.2
Kanaoka, Y.3
Nigrovic, P.A.4
Audoly, L.P.5
Austen, K.F.6
Lee, D.M.7
-
7
-
-
78149489303
-
Joint tissues amplify inflammation and alter their invasive behavior via leukotriene B4 in experimental inflammatory arthritis
-
Chen M, Lam BK, Luster AD, Zarini S, Murphy RC, Bair AM, Soberman RJ, and Lee DM. Joint tissues amplify inflammation and alter their invasive behavior via leukotriene B4 in experimental inflammatory arthritis. J Immunol 185: 5503-5511, 2010.
-
(2010)
J Immunol
, vol.185
, pp. 5503-5511
-
-
Chen, M.1
Lam, B.K.2
Luster, A.D.3
Zarini, S.4
Murphy, R.C.5
Bair, A.M.6
Soberman, R.J.7
Lee, D.M.8
-
8
-
-
9444249870
-
The transcription factor NRF2 protects against pulmonary fibrosis
-
DOI 10.1096/fj.03-1127fje
-
Cho HY, Reddy SP, Yamamoto M, and Kleeberger SR. The transcription factor NRF2 protects against pulmonary fibrosis. FASEB J 18: 1258-1260, 2004. (Pubitemid 39561569)
-
(2004)
FASEB Journal
, vol.18
, Issue.11
, pp. 1258-1260
-
-
Cho, H.-Y.1
Reddy, S.P.M.2
Yamamoto, M.3
Kleeberger, S.R.4
-
9
-
-
26844567619
-
Influence of heme oxygenase 1 modulation on the progression of murine collagen-induced arthritis
-
DOI 10.1002/art.21356
-
Devesa I, Ferrandiz ML, Terencio MC, Joosten LA, van den Berg WB, and Alcaraz MJ. Influence of heme oxygenase 1 modulation on the progression of murine collagen-induced arthritis. Arthritis Rheum 52: 3230-3238, 2005. (Pubitemid 41447106)
-
(2005)
Arthritis and Rheumatism
, vol.52
, Issue.10
, pp. 3230-3238
-
-
Devesa, I.1
Ferrandiz, M.L.2
Terencio, M.C.3
Joosten, L.A.B.4
Van Den Berg, W.B.5
Alcaraz, M.J.6
-
10
-
-
0032692402
-
The role of cytokines in the pathogenesis of rheumatoid arthritis
-
Feldmann M and Maini RN. The role of cytokines in the pathogenesis of rheumatoid arthritis. Rheumatology (Oxford) 38 Suppl 2: 3-7, 1999. (Pubitemid 29533264)
-
(1999)
Rheumatology
, vol.38
, Issue.SUPPL. 2
, pp. 3-7
-
-
Feldmann, M.1
Maini, R.N.2
-
11
-
-
0042736215
-
2 via the isoprostane pathway. A mechanism for the generation of bioactive prostaglandins independent of cyclooxygenase
-
DOI 10.1074/jbc.M303984200
-
Gao L, Zackert WE, Hasford JJ, Danekis ME, Milne GL, Remmert C, Reese J, Yin H, Tai HH, Dey SK, Porter NA, and Morrow JD. Formation of prostaglandin E2 and prostaglandin D2 via the isoprostane pathway: A mechanism for the generation of bioactive prostaglandins independent of the cyclooxygenase. J Biol Chem 278: 28479-28489, 2003. (Pubitemid 36935750)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.31
, pp. 28479-28489
-
-
Gao, L.1
Zackert, W.E.2
Hasford, J.J.3
Danekis, M.E.4
Milne, G.L.5
Remmert, C.6
Reese, J.7
Yin, H.8
Tai, H.-H.9
Dey, S.K.10
Porter, N.A.11
Morrow, J.D.12
-
12
-
-
10444242596
-
CC and CXC chemokine receptors mediate migration, proliferation, and matrix metalloproteinase production by fibroblast-like synoviocytes from rheumatoid arthritis patients
-
DOI 10.1002/art.20615
-
Garcia-Vicuna R, Gomez-Gaviro MV, Dominguez-Luis MJ, Pec MK, Gonzalez-Alvaro I, Alvaro-Gracia JM, and Diaz-Gonzalez F. CC and CXC chemokine receptors mediate migration, proliferation, and matrix metalloproteinase production by fibroblast-like synoviocytes from rheumatoid arthritis patients. Arthritis Rheum 50: 3866-3877, 2004. (Pubitemid 39643933)
-
(2004)
Arthritis and Rheumatism
, vol.50
, Issue.12
, pp. 3866-3877
-
-
Garcia-Vicuna, R.1
Gomez-Gaviro, M.V.2
Dominguez-Luis, M.J.3
Pec, M.K.4
Gonzalez-Alvaro, I.5
Alvaro-Gracia, J.M.6
Diaz-Gonzalez, F.7
-
13
-
-
25444468046
-
Divergent responses of chondrocytes and endothelial cells to shear stress: Cross-talk among COX-2, the phase 2 response, and apoptosis
-
DOI 10.1073/pnas.0506620102
-
Healy ZR, Lee NH, Gao X, Goldring MB, Talalay P, Kensler TW, and Konstantopoulos K. Divergent responses of chondrocytes and endothelial cells to shear stress: Cross-talk among COX-2, the phase 2 response, and apoptosis. Proc Natl Acad Sci USA 102: 14010-14015, 2005. (Pubitemid 41377694)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.39
, pp. 14010-14015
-
-
Healy, Z.R.1
Lee, N.H.2
Gao, X.3
Goldring, M.B.4
Talalay, P.5
Kensler, T.W.6
Konstantopoulos, K.7
-
14
-
-
33745871571
-
Nrf2 negatively regulates osteoblast differentiation via interfering with Runx2-dependent transcriptional activation
-
DOI 10.1074/jbc.M600603200
-
Hinoi E, Fujimori S, Wang L, Hojo H, Uno K, and Yoneda Y. Nrf2 negatively regulates osteoblast differentiation via interfering with Runx2-dependent transcriptional activation. J Biol Chem 281: 18015-18024, 2006. (Pubitemid 44035601)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.26
, pp. 18015-18024
-
-
Hinoi, E.1
Fujimori, S.2
Wang, L.3
Hojo, H.4
Uno, K.5
Yoneda, Y.6
-
15
-
-
33846003498
-
Nuclear factor E2 p45-related factor 2 negatively regulates chondrogenesis
-
DOI 10.1016/j.bone.2006.08.016, PII S8756328206006879
-
Hinoi E, Takarada T, Fujimori S, Wang L, Iemata M, Uno K, and Yoneda Y. Nuclear factor E2 p45-related factor 2 negatively regulates chondrogenesis. Bone 40: 337-344, 2007. (Pubitemid 46054553)
-
(2007)
Bone
, vol.40
, Issue.2
, pp. 337-344
-
-
Hinoi, E.1
Takarada, T.2
Fujimori, S.3
Wang, L.4
Iemata, M.5
Uno, K.6
Yoneda, Y.7
-
17
-
-
77955174319
-
Ablation of the transcription factor Nrf2 promotes ischemia-induced neovascularization by enhancing the inflammatory response
-
Ichihara S, Yamada Y, Liu F, Murohara T, Itoh K, Yamamoto M, and Ichihara G. Ablation of the transcription factor Nrf2 promotes ischemia-induced neovascularization by enhancing the inflammatory response. Arterioscler Thromb Vasc Biol 30: 1553-1561, 2010.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 1553-1561
-
-
Ichihara, S.1
Yamada, Y.2
Liu, F.3
Murohara, T.4
Itoh, K.5
Yamamoto, M.6
Ichihara, G.7
-
18
-
-
47949083810
-
The transcription factor Nrf2 is a therapeutic target against brain inflammation
-
Innamorato NG, Rojo AI, Garcia-Yague AJ, Yamamoto M, de Ceballos ML, and Cuadrado A. The transcription factor Nrf2 is a therapeutic target against brain inflammation. J Immunol 181: 680-689, 2008.
-
(2008)
J Immunol
, vol.181
, pp. 680-689
-
-
Innamorato, N.G.1
Rojo, A.I.2
Garcia-Yague, A.J.3
Yamamoto, M.4
De Ceballos, M.L.5
Cuadrado, A.6
-
19
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
DOI 10.1006/bbrc.1997.6943
-
Itoh K, Chiba T, Takahashi S, Ishii T, Igarashi K, Katoh Y, Oyake T, Hayashi N, Satoh K, Hatayama I, Yamamoto M, and Nabeshima Y. An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem Biophys Res Commun 236: 313-322, 1997. (Pubitemid 27373291)
-
(1997)
Biochemical and Biophysical Research Communications
, vol.236
, Issue.2
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
Ishii, T.4
Igarashi, K.5
Katoh, Y.6
Oyake, T.7
Hayashi, N.8
Satoh, K.9
Hatayama, I.10
Yamamoto, M.11
Nabeshima, Y.-I.12
-
20
-
-
77954235258
-
Deficiency of CXCR2, but not other chemokine receptors, attenuates autoantibody-mediated arthritis in a murine model
-
Jacobs JP, Ortiz-Lopez A, Campbell JJ, Gerard CJ, Mathis D, and Benoist C. Deficiency of CXCR2, but not other chemokine receptors, attenuates autoantibody-mediated arthritis in a murine model. Arthritis Rheum 62: 1921-1932, 2010.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 1921-1932
-
-
Jacobs, J.P.1
Ortiz-Lopez, A.2
Campbell, J.J.3
Gerard, C.J.4
Mathis, D.5
Benoist, C.6
-
21
-
-
59549099432
-
Disruption of Nrf2 enhances upregulation of nuclear factor-kappaB activity, proinflammatory cytokines, and intercellular adhesion molecule-1 in the brain after traumatic brain injury
-
Jin W, Wang H, Yan W, Xu L, Wang X, Zhao X, Yang X, Chen G, and Ji Y. Disruption of Nrf2 enhances upregulation of nuclear factor-kappaB activity, proinflammatory cytokines, and intercellular adhesion molecule-1 in the brain after traumatic brain injury. Mediators Inflamm 2008: 725174, 2008.
-
(2008)
Mediators Inflamm
, vol.2008
, pp. 725174
-
-
Jin, W.1
Wang, H.2
Yan, W.3
Xu, L.4
Wang, X.5
Zhao, X.6
Yang, X.7
Chen, G.8
Ji, Y.9
-
22
-
-
0035823540
-
Induction of cellular antioxidative stress genes through heterodimeric transcription factor Nrf2/small Maf by antirheumatic gold(I) compounds
-
Kataoka K, Handa H, and Nishizawa M. Induction of cellular antioxidative stress genes through heterodimeric transcription factor Nrf2/small Maf by antirheumatic gold(I) compounds. J Biol Chem 276: 34074-34081, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 34074-34081
-
-
Kataoka, K.1
Handa, H.2
Nishizawa, M.3
-
23
-
-
33846264538
-
Nrf2-deficient mice have an increased susceptibility to dextran sulfate sodium-induced colitis
-
DOI 10.1158/0008-5472.CAN-06-3562
-
Khor TO, Huang MT, Kwon KH, Chan JY, Reddy BS, and Kong AN. Nrf2-deficient mice have an increased susceptibility to dextran sulfate sodium-induced colitis. Cancer Res 66: 11580-11584, 2006. (Pubitemid 46094166)
-
(2006)
Cancer Research
, vol.66
, Issue.24
, pp. 11580-11584
-
-
Khor, T.O.1
Huang, M.-T.2
Kwon, K.H.3
Chan, J.Y.4
Reddy, B.S.5
Kong, A.-N.6
-
24
-
-
77955279350
-
A protective role of nuclear erythroid 2-related factor-2 (Nrf2) in inflammatory disorders
-
Kim J, Cha YN, and Surh YJ. A protective role of nuclear erythroid 2-related factor-2 (Nrf2) in inflammatory disorders. Mutat Res 690: 12-23, 2010.
-
(2010)
Mutat Res
, vol.690
, pp. 12-23
-
-
Kim, J.1
Cha, Y.N.2
Surh, Y.J.3
-
25
-
-
77956193657
-
NADPH oxidase-dependent reactive oxygen species mediate amplified TLR4 signaling and sepsis-induced mortality in Nrf2-deficient mice
-
Kong X, Thimmulappa R, Kombairaju P, and Biswal S. NADPH oxidase-dependent reactive oxygen species mediate amplified TLR4 signaling and sepsis-induced mortality in Nrf2-deficient mice. J Immunol 185: 569-577, 2010.
-
(2010)
J Immunol
, vol.185
, pp. 569-577
-
-
Kong, X.1
Thimmulappa, R.2
Kombairaju, P.3
Biswal, S.4
-
26
-
-
34547661858
-
2′,4′,6′-Tris(methoxymethoxy) chalcone protects against trinitrobenzene sulfonic acid-induced colitis and blocks tumor necrosis factor-α-induced intestinal epithelial inflammation via heme oxygenase 1-dependent and independent pathways
-
DOI 10.1016/j.bcp.2007.06.034, PII S0006295207004121
-
Lee SH, Sohn DH, Jin XY, Kim SW, Choi SC, and Seo GS. 2',4',6'-tris(methoxymethoxy) chalcone protects against trinitrobenzene sulfonic acid-induced colitis and blocks tumor necrosis factor-alpha-induced intestinal epithelial inflammation via heme oxygenase 1-dependent and independent pathways. Biochem Pharmacol 74: 870-880, 2007. (Pubitemid 47212081)
-
(2007)
Biochemical Pharmacology
, vol.74
, Issue.6
, pp. 870-880
-
-
Lee, S.H.1
Sohn, D.H.2
Jin, X.Y.3
Kim, S.W.4
Choi, S.C.5
Seo, G.S.6
-
27
-
-
33744729373
-
Multiorgan autoimmune inflammation, enhanced lymphoproliferation, and impaired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2
-
DOI 10.2353/ajpath.2006.051113
-
Ma Q, Battelli L, and Hubbs AF. Multiorgan autoimmune inflammation, enhanced lymphoproliferation, and impaired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2. Am J Pathol 168: 1960-1974, 2006. (Pubitemid 43825316)
-
(2006)
American Journal of Pathology
, vol.168
, Issue.6
, pp. 1960-1974
-
-
Ma, Q.1
Battelli, L.2
Hubbs, A.F.3
-
28
-
-
0037089664
-
Arthritogenic monoclonal antibodies from K/BxN mice
-
DOI 10.1084/jem.20011941
-
Maccioni M, Zeder-Lutz G, Huang H, Ebel C, Gerber P, Hergueux J, Marchal P, Duchatelle V, Degott C, van Regenmortel M, Benoist C, and Mathis D. Arthritogenic monoclonal antibodies from K/BxN mice. J Exp Med 195: 1071-1077, 2002. (Pubitemid 34412009)
-
(2002)
Journal of Experimental Medicine
, vol.195
, Issue.8
, pp. 1071-1077
-
-
Maccioni, M.1
Zeder-Lutz, G.2
Huang, H.3
Ebel, C.4
Gerber, P.5
Hergueux, J.6
Marchal, P.7
Duchatelle, V.8
Degott, C.9
Van Regenmortel, M.10
Benoist, C.11
Mathis, D.12
-
29
-
-
77951191161
-
The CO-releasing molecule CORM-3 protects against articular degradation in the K/BxN serum transfer arthritis model
-
Maicas N., Ferrandiz ML, Devesa I, Motterlini R, Koenders MI, van den Berg WB, and Alcaraz MJ. The CO-releasing molecule CORM-3 protects against articular degradation in the K/BxN serum transfer arthritis model. Eur J Pharmacol 634, 184-191, 2010.
-
(2010)
Eur J Pharmacol
, vol.634
, pp. 184-191
-
-
Maicas, N.1
Ferrandiz, M.L.2
Devesa, I.3
Motterlini, R.4
Koenders, M.I.5
Van Den Berg, W.B.6
Alcaraz, M.J.7
-
30
-
-
0036230130
-
How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease
-
DOI 10.1038/ni772
-
Matsumoto I, Maccioni M, Lee DM, Maurice M, Simmons B, Brenner M, Mathis D, and Benoist C. How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease. Nat Immunol 3: 360-365, 2002. (Pubitemid 34308624)
-
(2002)
Nature Immunology
, vol.3
, Issue.4
, pp. 360-365
-
-
Matsumoto, I.1
Maccioni, M.2
Lee, D.M.3
Maurice, M.4
Simmons, B.5
Brenner, M.6
Mathis, D.7
Benoist, C.8
-
31
-
-
0028061444
-
Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the β-globin locus control region
-
DOI 10.1073/pnas.91.21.9926
-
Moi P, Chan K, Asunis I, Cao A, and Kan YW. Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NFE2/AP1 repeat of the beta-globin locus control region. Proc Natl Acad Sci USA 91: 9926-9930, 1994. (Pubitemid 24311921)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.21
, pp. 9926-9930
-
-
Moi, P.1
Chan, K.2
Asunis, I.3
Cao, A.4
Kan, Y.W.5
-
32
-
-
0023774983
-
Selectivity of neutrophil 5-lipoxygenase and cyclooxygenase inhibition by an anti-inflammatory flavonoid glycoside and related aglycone flavonoids
-
Moroney MA, Alcaraz MJ, Forder RA, Carey F, and Hoult JRS. Selectivity of neutrophil 5-lipoxygenase and cyclooxygenase inhibition by an anti-inflammatory flavonoid glycoside and related aglycone flavonoids. J Pharm Pharmacol 40: 787-792, 1988.
-
(1988)
J Pharm Pharmacol
, vol.40
, pp. 787-792
-
-
Moroney, M.A.1
Alcaraz, M.J.2
Forder, R.A.3
Carey, F.4
Jrs, H.5
-
33
-
-
0030909913
-
The role of monocyte chemoattractant protein-1 (MCP-1) in the pathogenesis of collagen-induced arthritis in rats
-
DOI 10.1002/(SICI)1096-9896(199705)182:1<106::AID-PATH816>3.0.CO;2- A
-
Ogata H, Takeya M, Yoshimura T, Takagi K, and Takahashi K. The role of monocyte chemoattractant protein-1 (MCP-1) in the pathogenesis of collagen-induced arthritis in rats. J Pathol 182: 106-114, 1997. (Pubitemid 27240456)
-
(1997)
Journal of Pathology
, vol.182
, Issue.1
, pp. 106-114
-
-
Ogata, H.1
Takeya, M.2
Yoshimura, T.3
Takagi, K.4
Takahashi, K.5
-
34
-
-
47849083585
-
Nrf2 signaling: An adaptive response pathway for protection against environmental toxic insults
-
Osburn WO and Kensler TW. Nrf2 signaling: An adaptive response pathway for protection against environmental toxic insults. Mutat Res 659: 31-39, 2008.
-
(2008)
Mutat Res
, vol.659
, pp. 31-39
-
-
Osburn, W.O.1
Kensler, T.W.2
-
35
-
-
77649134594
-
Cilostazol enhances apoptosis of synovial cells from rheumatoid arthritis patients with inhibition of cytokine formation via Nrf2-linked heme oxygenase 1 induction
-
Park SY, Lee SW, Shin HK, Chung WT, Lee WS, Rhim BY, Hong KW, and Kim CD. Cilostazol enhances apoptosis of synovial cells from rheumatoid arthritis patients with inhibition of cytokine formation via Nrf2-linked heme oxygenase 1 induction. Arthritis Rheum 62: 732-741, 2010.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 732-741
-
-
Park, S.Y.1
Lee, S.W.2
Shin, H.K.3
Chung, W.T.4
Lee, W.S.5
Rhim, B.Y.6
Hong, K.W.7
Kim, C.D.8
-
36
-
-
0029985501
-
2 activity in the zymosan rat air pouch model of inflammation
-
Payá M, Terencio MC, Ferrándiz ML, and Alcaraz MJ. Involvement of secretory phospholipase A2 activity in the zymosan rat air pouch model of inflammation. Br J Pharmacol 117: 1773-1779, 1996. (Pubitemid 26121624)
-
(1996)
British Journal of Pharmacology
, vol.117
, Issue.8
, pp. 1773-1779
-
-
Paya, M.1
Terencio, M.C.2
Ferrandiz, M.L.3
Alcaraz, M.J.4
-
37
-
-
77950553993
-
Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity
-
Pi J, Leung L, Xue P, Wang W, Hou Y, Liu D, Yehuda-Shnaidman E, Lee C, Lau J, Kurtz TW, and Chan JY. Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity. J Biol Chem 285: 9292-9300, 2010.
-
(2010)
J Biol Chem
, vol.285
, pp. 9292-9300
-
-
Pi, J.1
Leung, L.2
Xue, P.3
Wang, W.4
Hou, Y.5
Liu, D.6
Yehuda-Shnaidman, E.7
Lee, C.8
Lau, J.9
Kurtz, T.W.10
Chan, J.Y.11
-
38
-
-
22344438250
-
Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice
-
DOI 10.1084/jem.20050538
-
Rangasamy T, Guo J, Mitzner WA, Roman J, Singh A, Fryer AD, Yamamoto M, Kensler TW, Tuder RM, Georas SN, and Biswal S. Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice. J Exp Med 202: 47-59, 2005. (Pubitemid 41002909)
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.1
, pp. 47-59
-
-
Rangasamy, T.1
Guo, J.2
Mitzner, W.A.3
Roman, J.4
Singh, A.5
Fryer, A.D.6
Yamamoto, M.7
Kensler, T.W.8
Tuder, R.M.9
Georas, S.N.10
Biswal, S.11
-
39
-
-
33644642974
-
Critical role of endothelial CXCR2 in LPS-induced neutrophil migration into the lung
-
DOI 10.1172/JCI27009
-
Reutershan J, Morris MA, Burcin TL, Smith DF, Chang D, Saprito MS, and Ley K. Critical role of endothelial CXCR2 in LPS-induced neutrophil migration into the lung. J Clin Invest 116: 695-702, 2006. (Pubitemid 43326878)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.3
, pp. 695-702
-
-
Reutershan, J.1
Morris, M.A.2
Burcin, T.L.3
Smith, D.F.4
Chang, D.5
Saprito, M.S.6
Ley, K.7
-
40
-
-
77749339881
-
Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease
-
Rojo AI, Innamorato NG, Martin-Moreno AM, de Ceballos ML, Yamamoto M, and Cuadrado A. Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease. GLIA 58: 588-598, 2010.
-
(2010)
GLIA
, vol.58
, pp. 588-598
-
-
Rojo, A.I.1
Innamorato, N.G.2
Martin-Moreno, A.M.3
De Ceballos, M.L.4
Yamamoto, M.5
Cuadrado, A.6
-
41
-
-
77957796093
-
Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung
-
Satoh H, Moriguchi T, Taguchi K, Takai J, Maher JM, Suzuki T, Winnard PT, Raman V, Ebina M, Nukiwa T, and Yamamoto M. Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung. Carcinogenesis 31: 1833-1843, 2010.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1833-1843
-
-
Satoh, H.1
Moriguchi, T.2
Taguchi, K.3
Takai, J.4
Maher, J.M.5
Suzuki, T.6
Winnard, P.T.7
Raman, V.8
Ebina, M.9
Nukiwa, T.10
Yamamoto, M.11
-
42
-
-
77952772125
-
IL-17-mediated monocyte migration occurs partially through CC chemokine ligand 2/monocyte chemoattractant protein-1 induction
-
Shahrara S, Pickens SR, Mandelin AM, Karpus WJ, Huang Q, Kolls JK, and Pope RM. IL-17-mediated monocyte migration occurs partially through CC chemokine ligand 2/monocyte chemoattractant protein-1 induction. J Immunol 184: 4479-4487, 2010.
-
(2010)
J Immunol
, vol.184
, pp. 4479-4487
-
-
Shahrara, S.1
Pickens, S.R.2
Mandelin, A.M.3
Karpus, W.J.4
Huang, Q.5
Kolls, J.K.6
Pope, R.M.7
-
43
-
-
59049108108
-
High affinity glycosaminoglycan and autoantigen interaction explains joint specificity in a mouse model of rheumatoid arthritis
-
Studelska DR, Mandik-Nayak L, Zhou X, Pan J, Weiser P, McDowell LM, Lu H, Liapis H, Allen PM, Shih FF, and Zhang L. High affinity glycosaminoglycan and autoantigen interaction explains joint specificity in a mouse model of rheumatoid arthritis. J Biol Chem 284: 2354-2362, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 2354-2362
-
-
Studelska, D.R.1
Mandik-Nayak, L.2
Zhou, X.3
Pan, J.4
Weiser, P.5
McDowell, L.M.6
Lu, H.7
Liapis, H.8
Allen, P.M.9
Shih, F.F.10
Zhang, L.11
-
44
-
-
56849124834
-
Disruption of Nrf2, a key inducer of antioxidant defenses, attenuates ApoE-mediated atherosclerosis in mice
-
Sussan TE, Jun J, Thimmulappa R, Bedja D, Antero M, Gabrielson KL, Polotsky VY, and Biswal S. Disruption of Nrf2, a key inducer of antioxidant defenses, attenuates ApoE-mediated atherosclerosis in mice. PLoS ONE 3: e3791, 2008.
-
(2008)
PLoS ONE
, vol.3
-
-
Sussan, T.E.1
Jun, J.2
Thimmulappa, R.3
Bedja, D.4
Antero, M.5
Gabrielson, K.L.6
Polotsky, V.Y.7
Biswal, S.8
-
45
-
-
33645530745
-
Nrf2 is a critical regu-lator of the innate immune response and survival during experimental sepsis
-
Thimmulappa RK, Lee H, Rangasamy T, Reddy SP, Yamamoto M, Kensler TW, and Biswal S. Nrf2 is a critical regu-lator of the innate immune response and survival during experimental sepsis. J Clin Invest 116: 984-995, 2006.
-
(2006)
J Clin Invest
, vol.116
, pp. 984-995
-
-
Thimmulappa, R.K.1
Lee, H.2
Rangasamy, T.3
Reddy, S.P.4
Yamamoto, M.5
Kensler, T.W.6
Biswal, S.7
-
46
-
-
70350152573
-
Systems biology guided by Chinese medicine reveals new markers for sub-typing rheumatoid arthritis patients
-
van Wietmarschen H, Yuan K, Lu C, Gao P, Wang J, Xiao C, Yan X, Wang M, Schroen J, Lu A, Xu G, and van der Greef J. Systems biology guided by Chinese medicine reveals new markers for sub-typing rheumatoid arthritis patients. J Clin Rheumatol 15: 330-337, 2009.
-
(2009)
J Clin Rheumatol
, vol.15
, pp. 330-337
-
-
Van Wietmarschen, H.1
Yuan, K.2
Lu, C.3
Gao, P.4
Wang, J.5
Xiao, C.6
Yan, X.7
Wang, M.8
Schroen, J.9
Lu, A.10
Xu, G.11
Van Der Greef, J.12
-
47
-
-
58149288682
-
Disruption of the transcription factor Nrf2 promotes pro-oxidative dendritic cells that stimulate Th2-like immunoresponsiveness upon activation by ambient particulate matter
-
Williams MA, Rangasamy T, Bauer SM, Killedar S, Karp M, Kensler TW, Yamamoto M, Breysse P, Biswal S, and Georas SN. Disruption of the transcription factor Nrf2 promotes pro-oxidative dendritic cells that stimulate Th2-like immunoresponsiveness upon activation by ambient particulate matter. J Immunol 181: 4545-4559, 2008.
-
(2008)
J Immunol
, vol.181
, pp. 4545-4559
-
-
Williams, M.A.1
Rangasamy, T.2
Bauer, S.M.3
Killedar, S.4
Karp, M.5
Kensler, T.W.6
Yamamoto, M.7
Breysse, P.8
Biswal, S.9
Georas, S.N.10
-
48
-
-
26244441526
-
Analysing the effect of novel therapies on cytokine expression in experimental arthritis
-
DOI 10.1111/j.0959-9673.2005.00443.x
-
Williams RO, Inglis JJ, Simelyte E, Criado G, and Sumariwalla PF. Analysing the effect of novel therapies on cytokine expression in experimental arthritis. Int J Exp Pathol 86: 267-278, 2005. (Pubitemid 41413622)
-
(2005)
International Journal of Experimental Pathology
, vol.86
, Issue.5
, pp. 267-278
-
-
Williams, R.O.1
Inglis, J.J.2
Simelyte, E.3
Criado, G.4
Sumariwalla, P.F.5
-
49
-
-
0035423403
-
Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis
-
Wipke BT and Allen PM. Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis. J Immunol 167: 1601-1608, 2001. (Pubitemid 32703161)
-
(2001)
Journal of Immunology
, vol.167
, Issue.3
, pp. 1601-1608
-
-
Wipke, B.T.1
Allen, P.M.2
-
50
-
-
79953313594
-
Role of oxidative stress in rheumatoid arthritis: Insights from the Nrf2-knockout mice
-
Wruck CJ, Fragoulis A, Gurzynski A, Brandenburg LO, Kan YW, Chan K, Hassenpflug J, Freitag-Wolf S, Varoga D, Lippross S, and Pufe T. Role of oxidative stress in rheumatoid arthritis: insights from the Nrf2-knockout mice. Ann Rheum Dis 70: 844-850, 2011.
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 844-850
-
-
Wruck, C.J.1
Fragoulis, A.2
Gurzynski, A.3
Brandenburg, L.O.4
Kan, Y.W.5
Chan, K.6
Hassenpflug, J.7
Freitag-Wolf, S.8
Varoga, D.9
Lippross, S.10
Pufe, T.11
-
51
-
-
35448988491
-
Promoter elements responsible for antioxidant regulation of MCP-1 gene expression
-
DOI 10.1089/ars.2007.1921
-
Xing L and Remick DG. Promoter elements responsible for antioxidant regulation of MCP-1 gene expression. Antioxid Redox Signal 9: 1979-1989, 2007. (Pubitemid 47622356)
-
(2007)
Antioxidants and Redox Signaling
, vol.9
, Issue.11
, pp. 1979-1989
-
-
Xing, L.1
Remick, D.G.2
-
52
-
-
0141427851
-
Nrf2 regulates thromboxane synthase gene expression in human lung cells
-
DOI 10.1089/10445490360708883
-
Yaekashiwa M and Wang LH. Nrf2 regulates thromboxane synthase gene expression in human lung cells. DNA Cell Biol 22: 479-487, 2003. (Pubitemid 37174746)
-
(2003)
DNA and Cell Biology
, vol.22
, Issue.8
, pp. 479-487
-
-
Yaekashiwa, M.1
Wang, L.-H.2
-
53
-
-
77958140054
-
The Nrf2-Keap1-ARE signaling pathway: The regulation and dual function of Nrf2 in cancer
-
Zhang DD. The Nrf2-Keap1-ARE signaling pathway: The regulation and dual function of Nrf2 in cancer. Antioxid Redox Signal 13: 1623-1626, 2010.
-
(2010)
Antioxid Redox Signal
, vol.13
, pp. 1623-1626
-
-
Zhang, D.D.1
-
54
-
-
27944437786
-
Activation of the Nrf2/antioxidant response pathway increases IL-8 expression
-
DOI 10.1002/eji.200526116
-
Zhang X, Chen X, Song H, Chen HZ, and Rovin BH. Activation of the Nrf2/antioxidant response pathway increases IL-8 expression. Eur J Immunol 35: 3258-3267, 2005. (Pubitemid 41672530)
-
(2005)
European Journal of Immunology
, vol.35
, Issue.11
, pp. 3258-3267
-
-
Zhang, X.1
Chen, X.2
Song, H.3
Chen, H.-Z.4
Rovin, B.H.5
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