α-Solanine Isolated From Solanum Tuberosum L. cv Jayoung Abrogates LPS-Induced Inflammatory Responses Via NF-κB Inactivation in RAW 264.7 Macrophages and Endotoxin-Induced Shock Model in Mice

Journal of Cellular Biochemistry

Volumn , Issue , 2016, Pages 2327-2339

  Shin, Ji Sun ^a,b   Lee, Kyoung Goo ^a   Lee, Hwi Ho ^a   Lee, Hae Jun ^a   An, Hyo Jin ^c   Nam, Jung Hwan ^d   Jang, Dae Sik ^a   Lee, Kyung Tae ^a  

^a Kyung Hee University   (South Korea)

^b Kyung Hee University Hospital   (South Korea)

^c Department of Computer and Electronic Physics   (South Korea)

^d National Institute of Animal Science   (South Korea)

Author keywords

CYCLOOXYGENASE; CYTOKINES; NITRIC OXIDE; NUCLEAR FACTOR B; SEPSIS; SOLANINE

Indexed keywords

ALPHA SOLANINE; ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; NITRIC OXIDE; PROSTAGLANDIN E2; SOLANINE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG ISOLATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LIPOPOLYSACCHARIDE-INDUCED ENDOTOXEMIA; MACROPHAGE ACTIVATION; MALE; MEDIATOR RELEASE; MIXED INFECTION; MOUSE; MOUSE MODEL; NONHUMAN; POTATO; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION; PROTECTION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAW 264.7 CELL LINE; SEPTIC SHOCK; SURVIVAL RATE;

EID: 84984972922     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.25530     Document Type: Article

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