Intranuclear interactomic inhibition of NF-κB suppresses LPS-induced severe sepsis

Biochemical and Biophysical Research Communications

Volumn 464, Issue 3, 2015, Pages 711-717

  Park, Sung Dong ^a   Cheon, So Yeong ^b   Park, Tae Yoon ^a   Shin, Bo Young ^a   Oh, Hyunju ^c   Ghosh, Sankar ^c   Koo, Bon Nyeo ^b   Lee, Sang Kyou ^a  

^a Yonsei University   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

^c Columbia University ^*  (United States)

Author keywords

Inflammation; Intra nucleus delivery; NF B; RelA (p65); Sepsis

Indexed keywords

GAMMA INTERFERON; I KAPPA B KINASE BETA; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; INTRA NUCLEAR TRANSDUCIBLE TRANSCRIPTION MODULATION DOMAIN TRANSCRIPTION FACTOR RELA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE ZAP 70; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; RECOMBINANT PROTEIN; RELA PROTEIN, HUMAN; RELA PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DNA BINDING; FEMALE; HELA CELL LINE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; INTRACELLULAR SIGNALING; LIPOPOLYSACCHARIDE-INDUCED SEPSIS; MALE; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REPORTER GENE; T LYMPHOCYTE ACTIVATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; GENETIC TRANSCRIPTION; GENETIC TRANSDUCTION; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; JURKAT CELL LINE; LYMPHOCYTE ACTIVATION; METABOLISM; PROTEIN TERTIARY STRUCTURE; SEPSIS; T LYMPHOCYTE;

ANIMALS; CELLS, CULTURED; CYTOKINES; FEMALE; HEK293 CELLS; HELA CELLS; HUMANS; JURKAT CELLS; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NF-KAPPA B; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEPSIS; T-LYMPHOCYTES; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION, GENETIC; TRANSDUCTION, GENETIC;

EID: 84938750032     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.07.008     Document Type: Article

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