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Volumn 120, Issue 6, 2016, Pages 692-701

Intestinal epithelial barrier function and tight junction proteins with heat and exercise

Author keywords

Exercise; Heat shock response; HSP70; Intestinal epithelial barrier

Indexed keywords

TIGHT JUNCTION PROTEIN;

EID: 84984674304     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00536.2015     Document Type: Review
Times cited : (249)

References (97)
  • 1
    • 38349124463 scopus 로고    scopus 로고
    • Regulation of tight junction assembly and epithelial morphogenesis by the heat shock protein Apg-2
    • Aijaz S, Sanchez-Heras E, Balda MS, Matter K. Regulation of tight junction assembly and epithelial morphogenesis by the heat shock protein Apg-2. BMC Cell Biol 8: 49, 2007.
    • (2007) BMC Cell Biol , vol.8 , pp. 49
    • Aijaz, S.1    Sanchez-Heras, E.2    Balda, M.S.3    Matter, K.4
  • 3
    • 84879114381 scopus 로고    scopus 로고
    • Mechanism of IL-1beta modulation of intestinal epithelial barrier involves p38 kinase and activating transcription factor-2 activation
    • Al-Sadi R, Guo S, Ye D, Dokladny K, Alhmoud T, Ereifej L, Said HM, Ma TY. Mechanism of IL-1beta modulation of intestinal epithelial barrier involves p38 kinase and activating transcription factor-2 activation. J Immunol 190: 6596-6606, 2013.
    • (2013) J Immunol , vol.190 , pp. 6596-6606
    • Al-Sadi, R.1    Guo, S.2    Ye, D.3    Dokladny, K.4    Alhmoud, T.5    Ereifej, L.6    Said, H.M.7    Ma, T.Y.8
  • 4
    • 84888263186 scopus 로고    scopus 로고
    • TNF-alpha modulation of intestinal epithelial tight junction barrier is regulated by ERK1/2 activation of Elk-1
    • Al-Sadi R, Guo S, Ye D, Ma TY. TNF-alpha modulation of intestinal epithelial tight junction barrier is regulated by ERK1/2 activation of Elk-1. Am J Pathol 183: 1871-1884, 2013.
    • (2013) Am J Pathol , vol.183 , pp. 1871-1884
    • Al-Sadi, R.1    Guo, S.2    Ye, D.3    Ma, T.Y.4
  • 5
    • 84899722895 scopus 로고    scopus 로고
    • Interleukin-6 modulation of intestinal epithelial tight junction permeability is mediated by JNK pathway activation of claudin-2 gene
    • Al-Sadi R, Ye D, Boivin M, Guo S, Hashimi M, Ereifej L, Ma TY. Interleukin-6 modulation of intestinal epithelial tight junction permeability is mediated by JNK pathway activation of claudin-2 gene. PloS One 9: e85345, 2014.
    • (2014) PloS One , vol.9 , pp. e85345
    • Al-Sadi, R.1    Ye, D.2    Boivin, M.3    Guo, S.4    Hashimi, M.5    Ereifej, L.6    Ma, T.Y.7
  • 6
    • 45949086355 scopus 로고    scopus 로고
    • Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability
    • Al-Sadi R, Ye D, Dokladny K, Ma TY. Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability. J Immunol 180: 5653-5661, 2008.
    • (2008) J Immunol , vol.180 , pp. 5653-5661
    • Al-Sadi, R.1    Ye, D.2    Dokladny, K.3    Ma, T.Y.4
  • 7
    • 0033122716 scopus 로고    scopus 로고
    • Early increase in intestinal permeability in patients with severe acute pancreatitis: Correlation with endotoxemia, organ failure, and mortality
    • Ammori BJ, Leeder PC, King RF, Barclay GR, Martin IG, Larvin M, McMahon MJ. Early increase in intestinal permeability in patients with severe acute pancreatitis: correlation with endotoxemia, organ failure, and mortality. J Gastrointest Surg 3: 252-262, 1999.
    • (1999) J Gastrointest Surg , vol.3 , pp. 252-262
    • Ammori, B.J.1    Leeder, P.C.2    King, R.F.3    Barclay, G.R.4    Martin, I.G.5    Larvin, M.6    McMahon, M.J.7
  • 10
    • 0025845787 scopus 로고
    • Endotoxemia and release of tumor necrosis factor and interleukin 1 alpha in acute heatstroke
    • Bouchama A, Parhar RS, el-Yazigi A, Sheth K, al-Sedairy S. Endotoxemia and release of tumor necrosis factor and interleukin 1 alpha in acute heatstroke. J Appl Physiol 70: 2640-2644, 1991.
    • (1991) J Appl Physiol , vol.70 , pp. 2640-2644
    • Bouchama, A.1    Parhar, R.S.2    El-Yazigi, A.3    Sheth, K.4    Al-Sedairy, S.5
  • 11
    • 14144253916 scopus 로고    scopus 로고
    • Intraperitoneal hyperthermic perfusion may induce bacterial translocation
    • Bozer M, Turkcapar N, Bayar S, Kocaoglu H. Intraperitoneal hyperthermic perfusion may induce bacterial translocation. Hepatogastroenterology 52: 111-114, 2005.
    • (2005) Hepatogastroenterology , vol.52 , pp. 111-114
    • Bozer, M.1    Turkcapar, N.2    Bayar, S.3    Kocaoglu, H.4
  • 13
    • 0030820387 scopus 로고    scopus 로고
    • Heat stress increases survival rates in lipopolysaccharide-stimulated rats
    • Chu EK, Ribeiro SP, Slutsky AS. Heat stress increases survival rates in lipopolysaccharide-stimulated rats. Crit Care Med 25: 1727-1732, 1997.
    • (1997) Crit Care Med , vol.25 , pp. 1727-1732
    • Chu, E.K.1    Ribeiro, S.P.2    Slutsky, A.S.3
  • 14
    • 0023912185 scopus 로고
    • The effect of hyperthermia and radiation on small bowel permeability using 51Cr EDTA and 14C mannitol in man
    • Coltart RS, Howard GC, Wraight EP, Bleehen NM. The effect of hyperthermia and radiation on small bowel permeability using 51Cr EDTA and 14C mannitol in man. Int J Hyperthermia 4: 467-477, 1988.
    • (1988) Int J Hyperthermia , vol.4 , pp. 467-477
    • Coltart, R.S.1    Howard, G.C.2    Wraight, E.P.3    Bleehen, N.M.4
  • 15
    • 84892651807 scopus 로고    scopus 로고
    • L-arginine supplementation prevents increases in intestinal permeability and bacterial translocation in male Swiss mice subjected to physical exercise under environmental heat stress
    • Costa KA, Soares AD, Wanner SP, Santos Rd, Fernandes SO, Martins Fdos S, Nicoli JR, Coimbra CC, Cardoso VN. L-arginine supplementation prevents increases in intestinal permeability and bacterial translocation in male Swiss mice subjected to physical exercise under environmental heat stress. J Nutr 144: 218-223, 2014.
    • (2014) J Nutr , vol.144 , pp. 218-223
    • Costa, K.A.1    Soares, A.D.2    Wanner, S.P.3    Santos, R.D.4    Fernandes, S.O.5    Martins Fdos, S.6    Nicoli, J.R.7    Coimbra, C.C.8    Cardoso, V.N.9
  • 16
    • 0030805693 scopus 로고    scopus 로고
    • Systemic inflammatory response syndrome
    • Davies MG, Hagen PO. Systemic inflammatory response syndrome. Br J Surg 84: 920-935, 1997.
    • (1997) Br J Surg , vol.84 , pp. 920-935
    • Davies, M.G.1    Hagen, P.O.2
  • 18
    • 0029862538 scopus 로고    scopus 로고
    • Involvement of a heterotrimeric G protein alpha subunit in tight junction biogenesis
    • Denker BM, Saha C, Khawaja S, Nigam SK. Involvement of a heterotrimeric G protein alpha subunit in tight junction biogenesis. J Biol Chem 271: 25750-25753, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 25750-25753
    • Denker, B.M.1    Saha, C.2    Khawaja, S.3    Nigam, S.K.4
  • 19
    • 77950358769 scopus 로고    scopus 로고
    • LPS-induced cytokine levels are repressed by elevated expression of HSP70 in rats: Possible role of NF-kappaB
    • Dokladny K, Lobb R, Wharton W, Ma TY, Moseley PL. LPS-induced cytokine levels are repressed by elevated expression of HSP70 in rats: possible role of NF-kappaB. Cell Stress Chaperones 15: 153-163, 2010.
    • (2010) Cell Stress Chaperones , vol.15 , pp. 153-163
    • Dokladny, K.1    Lobb, R.2    Wharton, W.3    Ma, T.Y.4    Moseley, P.L.5
  • 20
    • 33644856858 scopus 로고    scopus 로고
    • Physiologically relevant increase in temperature causes an increase in intestinal epithelial tight junction permeability
    • Dokladny K, Moseley PL, Ma TY. Physiologically relevant increase in temperature causes an increase in intestinal epithelial tight junction permeability. Am J Physiol Gastrointest Liver Physiol 290: G204-G212, 2006.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290 , pp. G204-G212
    • Dokladny, K.1    Moseley, P.L.2    Ma, T.Y.3
  • 21
    • 33748416881 scopus 로고    scopus 로고
    • Induction of physiological thermotolerance in MDCK monolayers: Contribution of heat shock protein 70
    • Dokladny K, Wharton W, Lobb R, Ma TY, Moseley PL. Induction of physiological thermotolerance in MDCK monolayers: contribution of heat shock protein 70. Cell Stress Chaperones 11: 268-275, 2006.
    • (2006) Cell Stress Chaperones , vol.11 , pp. 268-275
    • Dokladny, K.1    Wharton, W.2    Lobb, R.3    Ma, T.Y.4    Moseley, P.L.5
  • 22
    • 55449107870 scopus 로고    scopus 로고
    • Lack of cross-tolerance following heat and cadmium exposure in functional MDCK monolayers
    • Dokladny K, Wharton W, Ma TY, Moseley PL. Lack of cross-tolerance following heat and cadmium exposure in functional MDCK monolayers. J Appl Toxicol 28: 885-894, 2008.
    • (2008) J Appl Toxicol , vol.28 , pp. 885-894
    • Dokladny, K.1    Wharton, W.2    Ma, T.Y.3    Moseley, P.L.4
  • 23
    • 40449135547 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of heat stress-induced up-regulation of occludin protein expression: Regulatory role of heat shock factor-1
    • Dokladny K, Ye D, Kennedy JC, Moseley PL, Ma TY. Cellular and molecular mechanisms of heat stress-induced up-regulation of occludin protein expression: regulatory role of heat shock factor-1. Am J Pathol 172: 659-670, 2008.
    • (2008) Am J Pathol , vol.172 , pp. 659-670
    • Dokladny, K.1    Ye, D.2    Kennedy, J.C.3    Moseley, P.L.4    Ma, T.Y.5
  • 24
    • 59449086585 scopus 로고    scopus 로고
    • Phosphorylation of Tyr-398 and Tyr-402 in occludin prevents its interaction with ZO-1 and destabilizes its assembly at the tight junctions
    • Elias BC, Suzuki T, Seth A, Giorgianni F, Kale G, Shen L, Turner JR, Naren A, Desiderio DM, Rao R. Phosphorylation of Tyr-398 and Tyr-402 in occludin prevents its interaction with ZO-1 and destabilizes its assembly at the tight junctions. J Biol Chem 284: 1559-1569, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 1559-1569
    • Elias, B.C.1    Suzuki, T.2    Seth, A.3    Giorgianni, F.4    Kale, G.5    Shen, L.6    Turner, J.R.7    Naren, A.8    Desiderio, D.M.9    Rao, R.10
  • 25
    • 0035106651 scopus 로고    scopus 로고
    • The role of the gut in the pathogenesis of death due to hyperthermia
    • Eshel GM, Safar P, Stezoski W. The role of the gut in the pathogenesis of death due to hyperthermia. Am J Forensic Med Pathol 22: 100-104, 2001.
    • (2001) Am J Forensic Med Pathol , vol.22 , pp. 100-104
    • Eshel, G.M.1    Safar, P.2    Stezoski, W.3
  • 26
    • 0033560065 scopus 로고    scopus 로고
    • PDZ domains: Fundamental building blocks in the organization of protein complexes at the plasma membrane
    • Fanning AS, Anderson JM. PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membrane. J Clin Invest 103: 767-772, 1999.
    • (1999) J Clin Invest , vol.103 , pp. 767-772
    • Fanning, A.S.1    Anderson, J.M.2
  • 27
    • 0023604564 scopus 로고
    • Time course of endotoxemia and cardiovascular changes in heat-stressed primates
    • Gathiram P, Gaffin SL, Brock-Utne JG, Wells MT. Time course of endotoxemia and cardiovascular changes in heat-stressed primates. Aviat Space Environ Med 58: 1071-1074, 1987.
    • (1987) Aviat Space Environ Med , vol.58 , pp. 1071-1074
    • Gathiram, P.1    Gaffin, S.L.2    Brock-Utne, J.G.3    Wells, M.T.4
  • 28
    • 0023618826 scopus 로고
    • Antilipopolysaccharide improves survival in primates subjected to heat stroke
    • Gathiram P, Wells MT, Brock-Utne JG, Gaffin SL. Antilipopolysaccharide improves survival in primates subjected to heat stroke. Circ Shock 23: 157-164, 1987.
    • (1987) Circ Shock , vol.23 , pp. 157-164
    • Gathiram, P.1    Wells, M.T.2    Brock-Utne, J.G.3    Gaffin, S.L.4
  • 29
    • 0023952302 scopus 로고
    • Prophylactic corticosteroid increases survival in experimental heat stroke in primates
    • Gathiram P, Wells MT, Brock-Utne JG, Gaffin SL. Prophylactic corticosteroid increases survival in experimental heat stroke in primates. Aviat Space Environ Med 59: 352-355, 1988.
    • (1988) Aviat Space Environ Med , vol.59 , pp. 352-355
    • Gathiram, P.1    Wells, M.T.2    Brock-Utne, J.G.3    Gaffin, S.L.4
  • 31
    • 0023772589 scopus 로고
    • Portal and systemic plasma lipopolysaccharide concentrations in heat-stressed primates
    • Gathiram P, Wells MT, Raidoo D, Brock-Utne JG, Gaffin SL. Portal and systemic plasma lipopolysaccharide concentrations in heat-stressed primates. Circ Shock 25: 223-230, 1988.
    • (1988) Circ Shock , vol.25 , pp. 223-230
    • Gathiram, P.1    Wells, M.T.2    Raidoo, D.3    Brock-Utne, J.G.4    Gaffin, S.L.5
  • 32
    • 13144252170 scopus 로고    scopus 로고
    • The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein
    • Giepmans BN, Moolenaar WH. The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein. Curr Biol 8: 931-934, 1998.
    • (1998) Curr Biol , vol.8 , pp. 931-934
    • Giepmans, B.N.1    Moolenaar, W.H.2
  • 33
    • 84872724877 scopus 로고    scopus 로고
    • Lipopolysaccharide causes an increase in intestinal tight junction permeability in vitro and in vivo by inducing enterocyte membrane expression and localization of TLR-4 and CD14
    • Guo S, Al-Sadi R, Said HM, Ma TY. Lipopolysaccharide causes an increase in intestinal tight junction permeability in vitro and in vivo by inducing enterocyte membrane expression and localization of TLR-4 and CD14. Am J Pathol 182: 375-387, 2013.
    • (2013) Am J Pathol , vol.182 , pp. 375-387
    • Guo, S.1    Al-Sadi, R.2    Said, H.M.3    Ma, T.Y.4
  • 34
    • 84894665620 scopus 로고    scopus 로고
    • Acute exercises induce disorders of the gastrointestinal integrity in a murine model
    • Gutekunst K, Kruger K, August C, Diener M, Mooren FC. Acute exercises induce disorders of the gastrointestinal integrity in a murine model. Eur J Appl Physiol 114: 609-617, 2014.
    • (2014) Eur J Appl Physiol , vol.114 , pp. 609-617
    • Gutekunst, K.1    Kruger, K.2    August, C.3    Diener, M.4    Mooren, F.C.5
  • 38
    • 18244384957 scopus 로고    scopus 로고
    • Reorganization of ZO-1 by sodium-dependent glucose transporter activation after heat stress in LLC-PK1 cells
    • Ikari A, Nakano M, Suketa Y, Harada H, Takagi K. Reorganization of ZO-1 by sodium-dependent glucose transporter activation after heat stress in LLC-PK1 cells. J Cell Physiol 203: 471-478, 2005.
    • (2005) J Cell Physiol , vol.203 , pp. 471-478
    • Ikari, A.1    Nakano, M.2    Suketa, Y.3    Harada, H.4    Takagi, K.5
  • 39
    • 0033552629 scopus 로고    scopus 로고
    • Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins
    • Itoh M, Furuse M, Morita K, Kubota K, Saitou M, Tsukita S. Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins. J Cell Biol 147: 1351-1363, 1999.
    • (1999) J Cell Biol , vol.147 , pp. 1351-1363
    • Itoh, M.1    Furuse, M.2    Morita, K.3    Kubota, K.4    Saitou, M.5    Tsukita, S.6
  • 40
    • 0034038566 scopus 로고    scopus 로고
    • Intestinal permeability is increased in patients with intermittent claudication
    • Iwata H, Matsushita M, Nishikimi N, Sakurai T, Nimura Y. Intestinal permeability is increased in patients with intermittent claudication. J Vasc Surg 31: 1003-1007, 2000.
    • (2000) J Vasc Surg , vol.31 , pp. 1003-1007
    • Iwata, H.1    Matsushita, M.2    Nishikimi, N.3    Sakurai, T.4    Nimura, Y.5
  • 41
    • 0033959186 scopus 로고    scopus 로고
    • Relationship between gastro-intestinal complaints and endotoxaemia, cytokine release and the acute-phase reaction during and after a long-distance triathlon in highly trained men
    • Jeukendrup AE, Vet-Joop K, Sturk A, Stegen JH, Senden J, Saris WH, Wagenmakers AJ. Relationship between gastro-intestinal complaints and endotoxaemia, cytokine release and the acute-phase reaction during and after a long-distance triathlon in highly trained men. Clin Sci 98: 47-55, 2000.
    • (2000) Clin Sci , vol.98 , pp. 47-55
    • Jeukendrup, A.E.1    Vet-Joop, K.2    Sturk, A.3    Stegen, J.H.4    Senden, J.5    Saris, W.H.6    Wagenmakers, A.J.7
  • 42
    • 0023923279 scopus 로고
    • Peripheral vascular responses to hyperthermia in the rat
    • Kregel KC, Wall PT, Gisolfi CV. Peripheral vascular responses to hyperthermia in the rat. J Appl Physiol 64: 2582-2588, 1988.
    • (1988) J Appl Physiol , vol.64 , pp. 2582-2588
    • Kregel, K.C.1    Wall, P.T.2    Gisolfi, C.V.3
  • 45
    • 50149098362 scopus 로고    scopus 로고
    • Intestinal barrier dysfunction, endotoxemia, and gastrointestinal symptoms: The 'canary in the coal mine' during exercise-heat stress?
    • Lambert GP. Intestinal barrier dysfunction, endotoxemia, and gastrointestinal symptoms: the 'canary in the coal mine' during exercise-heat stress? Med Sport Sci 53: 61-73, 2008.
    • (2008) Med Sport Sci , vol.53 , pp. 61-73
    • Lambert, G.P.1
  • 47
    • 0035005586 scopus 로고    scopus 로고
    • Gastrointestinal permeability during exercise: Effects of aspirin and energy-containing beverages
    • Lambert GP, Broussard LJ, Mason BL, Mauermann WJ, Gisolfi CV. Gastrointestinal permeability during exercise: effects of aspirin and energy-containing beverages. J Appl Physiol 90: 2075-2080, 2001.
    • (2001) J Appl Physiol , vol.90 , pp. 2075-2080
    • Lambert, G.P.1    Broussard, L.J.2    Mason, B.L.3    Mauermann, W.J.4    Gisolfi, C.V.5
  • 48
    • 0036089845 scopus 로고    scopus 로고
    • Selected contribution: Hyperthermia-induced intestinal permeability and the role of oxidative and nitrosative stress
    • discussion 1749
    • Lambert GP, Gisolfi CV, Berg DJ, Moseley PL, Oberley LW, Kregel KC. Selected contribution: hyperthermia-induced intestinal permeability and the role of oxidative and nitrosative stress. J Appl Physiol 92: 1750-1761; discussion 1749, 2002.
    • (2002) J Appl Physiol , vol.92 , pp. 1750-1761
    • Lambert, G.P.1    Gisolfi, C.V.2    Berg, D.J.3    Moseley, P.L.4    Oberley, L.W.5    Kregel, K.C.6
  • 52
    • 12744273443 scopus 로고    scopus 로고
    • Heat shock treatment protects osmotic stress-induced dysfunction of the blood-brain barrier through preservation of tight junction proteins
    • Lu TS, Chen HW, Huang MH, Wang SJ, Yang RC. Heat shock treatment protects osmotic stress-induced dysfunction of the blood-brain barrier through preservation of tight junction proteins. Cell Stress Chaperones 9: 369-377, 2004.
    • (2004) Cell Stress Chaperones , vol.9 , pp. 369-377
    • Lu, T.S.1    Chen, H.W.2    Huang, M.H.3    Wang, S.J.4    Yang, R.C.5
  • 53
    • 0027260315 scopus 로고
    • Heat shock protects neuronal cells from programmed cell death by apoptosis
    • Mailhos C, Howard MK, Latchman DS. Heat shock protects neuronal cells from programmed cell death by apoptosis. Neuroscience 55: 621-627, 1993.
    • (1993) Neuroscience , vol.55 , pp. 621-627
    • Mailhos, C.1    Howard, M.K.2    Latchman, D.S.3
  • 54
    • 84872468862 scopus 로고
    • Heat stroke; A clinico-pathologic study of 125 fatal cases
    • Malamud N, Haymaker W, Custer RP. Heat stroke; a clinico-pathologic study of 125 fatal cases. Mil Surg 99: 397-449, 1946.
    • (1946) Mil Surg , vol.99 , pp. 397-449
    • Malamud, N.1    Haymaker, W.2    Custer, R.P.3
  • 57
    • 0027169447 scopus 로고
    • New frontiers in thermoregulation and exercise
    • Moseley PL, Gisolfi CV. New frontiers in thermoregulation and exercise. Sports Med 16: 163-167, 1993.
    • (1993) Sports Med , vol.16 , pp. 163-167
    • Moseley, P.L.1    Gisolfi, C.V.2
  • 58
    • 0029937874 scopus 로고    scopus 로고
    • Induction of heat shock protein 70 protects intestinal epithelial IEC-18 cells from oxidant and thermal injury
    • Musch MW, Ciancio MJ, Sarge K, Chang EB. Induction of heat shock protein 70 protects intestinal epithelial IEC-18 cells from oxidant and thermal injury. Am J Physiol Cell Physiol 270: C429-C436, 1996.
    • (1996) Am J Physiol Cell Physiol , vol.270 , pp. C429-C436
    • Musch, M.W.1    Ciancio, M.J.2    Sarge, K.3    Chang, E.B.4
  • 59
    • 0032992511 scopus 로고    scopus 로고
    • Heat-shock protein 72 protects against oxidant-induced injury of barrier function of human colonic epithelial Caco2/bbe cells
    • Musch MW, Sugi K, Straus D, Chang EB. Heat-shock protein 72 protects against oxidant-induced injury of barrier function of human colonic epithelial Caco2/bbe cells. Gastroenterology 117: 115-122, 1999.
    • (1999) Gastroenterology , vol.117 , pp. 115-122
    • Musch, M.W.1    Sugi, K.2    Straus, D.3    Chang, E.B.4
  • 65
    • 0942298580 scopus 로고    scopus 로고
    • Reduction in heat-induced gastrointestinal hyperpermeability in rats by bovine colostrum and goat milk powders
    • Prosser C, Stelwagen K, Cummins R, Guerin P, Gill N, Milne C. Reduction in heat-induced gastrointestinal hyperpermeability in rats by bovine colostrum and goat milk powders. J Appl Physiol 96: 650-654, 2004.
    • (2004) J Appl Physiol , vol.96 , pp. 650-654
    • Prosser, C.1    Stelwagen, K.2    Cummins, R.3    Guerin, P.4    Gill, N.5    Milne, C.6
  • 67
    • 67249146480 scopus 로고    scopus 로고
    • Occludin phosphorylation in regulation of epithelial tight junctions
    • Rao R. Occludin phosphorylation in regulation of epithelial tight junctions. Ann NY Acad Sci 1165: 62-68, 2009.
    • (2009) Ann NY Acad Sci , vol.1165 , pp. 62-68
    • Rao, R.1
  • 69
    • 84886412961 scopus 로고    scopus 로고
    • Chaperone machines for protein folding, unfolding and disaggregation
    • Saibil H. Chaperone machines for protein folding, unfolding and disaggregation. Nat Rev Mol Cell Biol 14: 630-642, 2013.
    • (2013) Nat Rev Mol Cell Biol , vol.14 , pp. 630-642
    • Saibil, H.1
  • 70
    • 33947367807 scopus 로고    scopus 로고
    • Oxidative stress and ischemia-reperfusion injury in gastrointestinal tract and antioxidant, protective agents
    • Sasaki M, Joh T. Oxidative stress and ischemia-reperfusion injury in gastrointestinal tract and antioxidant, protective agents. J Clin Biochem Nutr 40: 1-12, 2007.
    • (2007) J Clin Biochem Nutr , vol.40 , pp. 1-12
    • Sasaki, M.1    Joh, T.2
  • 71
    • 51149090815 scopus 로고    scopus 로고
    • Mild endotoxemia, NF-B translocation, and cytokine increase during exertional heat stress in trained and untrained individuals
    • Selkirk GA, McLellan TM, Wright HE, Rhind SG. Mild endotoxemia, NF-B translocation, and cytokine increase during exertional heat stress in trained and untrained individuals. Am J Physiol Regul Integr Comp Physiol 295: R611-R623, 2008.
    • (2008) Am J Physiol Regul Integr Comp Physiol , vol.295 , pp. R611-R623
    • Selkirk, G.A.1    McLellan, T.M.2    Wright, H.E.3    Rhind, S.G.4
  • 73
    • 27744515500 scopus 로고    scopus 로고
    • Transiently enhanced LPS-induced fever following hyperthermic stress in rabbits
    • Shibata M, Uno T, Riedel W, Nishimaki M, Watanabe K. Transiently enhanced LPS-induced fever following hyperthermic stress in rabbits. Int J Biometeorol 50: 67-74, 2005.
    • (2005) Int J Biometeorol , vol.50 , pp. 67-74
    • Shibata, M.1    Uno, T.2    Riedel, W.3    Nishimaki, M.4    Watanabe, K.5
  • 75
    • 33646084611 scopus 로고    scopus 로고
    • Oral glutamine enhances heat shock protein expression and improves survival following hyperthermia
    • Singleton KD, Wischmeyer PE. Oral glutamine enhances heat shock protein expression and improves survival following hyperthermia. Shock 25: 295-299, 2006.
    • (2006) Shock , vol.25 , pp. 295-299
    • Singleton, K.D.1    Wischmeyer, P.E.2
  • 77
    • 84922392936 scopus 로고    scopus 로고
    • Dietary glutamine prevents the loss of intestinal barrier function and attenuates the increase in core body temperature induced by acute heat exposure
    • Soares AD, Costa KA, Wanner SP, Santos RG, Fernandes SO, Martins FS, Nicoli JR, Coimbra CC, Cardoso VN. Dietary glutamine prevents the loss of intestinal barrier function and attenuates the increase in core body temperature induced by acute heat exposure. Br J Nutr 112: 1601-1610, 2014.
    • (2014) Br J Nutr , vol.112 , pp. 1601-1610
    • Soares, A.D.1    Costa, K.A.2    Wanner, S.P.3    Santos, R.G.4    Fernandes, S.O.5    Martins, F.S.6    Nicoli, J.R.7    Coimbra, C.C.8    Cardoso, V.N.9
  • 78
    • 0037106581 scopus 로고    scopus 로고
    • APKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization
    • Suzuki A, Ishiyama C, Hashiba K, Shimizu M, Ebnet K, Ohno S. aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization. J Cell Sci 115: 3565-3573, 2002.
    • (2002) J Cell Sci , vol.115 , pp. 3565-3573
    • Suzuki, A.1    Ishiyama, C.2    Hashiba, K.3    Shimizu, M.4    Ebnet, K.5    Ohno, S.6
  • 79
    • 0035911955 scopus 로고    scopus 로고
    • Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures
    • Suzuki A, Yamanaka T, Hirose T, Manabe N, Mizuno K, Shimizu M, Akimoto K, Izumi Y, Ohnishi T, Ohno S. Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures. J Cell Biol 152: 1183-1196, 2001.
    • (2001) J Cell Biol , vol.152 , pp. 1183-1196
    • Suzuki, A.1    Yamanaka, T.2    Hirose, T.3    Manabe, N.4    Mizuno, K.5    Shimizu, M.6    Akimoto, K.7    Izumi, Y.8    Ohnishi, T.9    Ohno, S.10
  • 81
    • 0027027774 scopus 로고
    • The effects of local hyperthermia on the morphology of the small bowel
    • Toth T, Fenyvesi A, Klemm I. The effects of local hyperthermia on the morphology of the small bowel. Acta Physiol Hung 80: 293-301, 1992.
    • (1992) Acta Physiol Hung , vol.80 , pp. 293-301
    • Toth, T.1    Fenyvesi, A.2    Klemm, I.3
  • 82
    • 33644861530 scopus 로고    scopus 로고
    • The heat-shock protein Apg-2 binds to the tight junction protein ZO-1 and regulates transcriptional activity of ZONAB
    • Tsapara A, Matter K, Balda MS. The heat-shock protein Apg-2 binds to the tight junction protein ZO-1 and regulates transcriptional activity of ZONAB. Mol Biol Cell 17: 1322-1330, 2006.
    • (2006) Mol Biol Cell , vol.17 , pp. 1322-1330
    • Tsapara, A.1    Matter, K.2    Balda, M.S.3
  • 83
    • 70350509805 scopus 로고    scopus 로고
    • Intestinal mucosal barrier function in health and disease
    • Turner JR. Intestinal mucosal barrier function in health and disease. Nat Rev Immunol 9: 799-809, 2009.
    • (2009) Nat Rev Immunol , vol.9 , pp. 799-809
    • Turner, J.R.1
  • 85
    • 84912106825 scopus 로고    scopus 로고
    • The role of molecular remodeling in differential regulation of tight junction permeability
    • Turner JR, Buschmann MM, Romero-Calvo I, Sailer A, Shen L. The role of molecular remodeling in differential regulation of tight junction permeability. Semin Cell Dev Biol 36: 204-212, 2014.
    • (2014) Semin Cell Dev Biol , vol.36 , pp. 204-212
    • Turner, J.R.1    Buschmann, M.M.2    Romero-Calvo, I.3    Sailer, A.4    Shen, L.5
  • 88
    • 84912092373 scopus 로고    scopus 로고
    • Architecture of tight junctions and principles of molecular composition
    • Van Itallie CM, Anderson JM. Architecture of tight junctions and principles of molecular composition. Semin Cell Dev Biol 36: 157-165, 2014.
    • (2014) Semin Cell Dev Biol , vol.36 , pp. 157-165
    • Van Itallie, C.M.1    Anderson, J.M.2
  • 91
    • 13244298599 scopus 로고    scopus 로고
    • Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression
    • Wang F, Graham WV, Wang Y, Witkowski ED, Schwarz BT, Turner JR. Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression. Am J Pathol 166: 409-419, 2005.
    • (2005) Am J Pathol , vol.166 , pp. 409-419
    • Wang, F.1    Graham, W.V.2    Wang, Y.3    Witkowski, E.D.4    Schwarz, B.T.5    Turner, J.R.6
  • 92
    • 0022527491 scopus 로고
    • Endotoxaemia in active Crohn's disease Treatment with whole gut irrigation and 5-aminosalicylic acid
    • Wellmann W, Fink PC, Benner F, Schmidt FW. Endotoxaemia in active Crohn's disease. Treatment with whole gut irrigation and 5-aminosalicylic acid. Gut 27: 814-820, 1986.
    • (1986) Gut , vol.27 , pp. 814-820
    • Wellmann, W.1    Fink, P.C.2    Benner, F.3    Schmidt, F.W.4
  • 93
    • 0033521140 scopus 로고    scopus 로고
    • Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3
    • Wittchen ES, Haskins J, Stevenson BR. Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3. J Biol Chem 274: 35179-35185, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 35179-35185
    • Wittchen, E.S.1    Haskins, J.2    Stevenson, B.R.3
  • 94
    • 84884183090 scopus 로고    scopus 로고
    • Eicosapentaenoic acid enhances heat stress-impaired intestinal epithelial barrier function in Caco-2 cells
    • Xiao G, Tang L, Yuan F, Zhu W, Zhang S, Liu Z, Geng Y, Qiu X, Zhang Y, Su L. Eicosapentaenoic acid enhances heat stress-impaired intestinal epithelial barrier function in Caco-2 cells. PloS One 8: e73571, 2013.
    • (2013) PloS One , vol.8 , pp. e73571
    • Xiao, G.1    Tang, L.2    Yuan, F.3    Zhu, W.4    Zhang, S.5    Liu, Z.6    Geng, Y.7    Qiu, X.8    Zhang, Y.9    Su, L.10
  • 95
    • 34948818178 scopus 로고    scopus 로고
    • Investigation into the signal transduction pathway via which heat stress impairs intestinal epithelial barrier function
    • Yang PC, He SH, Zheng PY. Investigation into the signal transduction pathway via which heat stress impairs intestinal epithelial barrier function. J Gastroenterol Hepatol 22: 1823-1831, 2007.
    • (2007) J Gastroenterol Hepatol , vol.22 , pp. 1823-1831
    • Yang, P.C.1    He, S.H.2    Zheng, P.Y.3
  • 96
    • 84914691351 scopus 로고    scopus 로고
    • The effects of acute oral glutamine supplementation on exerciseinduced gastrointestinal permeability and heat shock protein expression in peripheral blood mononuclear cells
    • Zuhl M, Dokladny K, Mermier C, Schneider S, Salgado R, Moseley P. The effects of acute oral glutamine supplementation on exerciseinduced gastrointestinal permeability and heat shock protein expression in peripheral blood mononuclear cells. Cell Stress Chaperones 20: 85-93, 2015.
    • (2015) Cell Stress Chaperones , vol.20 , pp. 85-93
    • Zuhl, M.1    Dokladny, K.2    Mermier, C.3    Schneider, S.4    Salgado, R.5    Moseley, P.6
  • 97
    • 84892913547 scopus 로고    scopus 로고
    • Effects of oral glutamine supplementation on exercise-induced gastrointestinal permeability and tight junction protein expression
    • Zuhl MN, Lanphere KR, Kravitz L, Mermier CM, Schneider S, Dokladny K, Moseley PL. Effects of oral glutamine supplementation on exercise-induced gastrointestinal permeability and tight junction protein expression. J Appl Physiol 116: 183-191, 2014.
    • (2014) J Appl Physiol , vol.116 , pp. 183-191
    • Zuhl, M.N.1    Lanphere, K.R.2    Kravitz, L.3    Mermier, C.M.4    Schneider, S.5    Dokladny, K.6    Moseley, P.L.7


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