Phosphorylation of Tyr-398 and Tyr-402 in occludin prevents Its interaction with ZO-1 and destabilizes Its assembly at the tight junctions

Journal of Biological Chemistry

Volumn 284, Issue 3, 2009, Pages 1559-1569

  Elias, Bertha C ^a   Suzuki, Takuya ^a   Seth, Ankur ^a   Giorgianni, Francesco ^b   Kale, Gautam ^a   Shan, Le ^c   Turner, Jerrold R ^a   Naren, Anjaparavanda ^c   Desiderio, Dominic M ^b   Rao, Radhakrishna ^a,b  

^a Department of Physiology ^*  (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C-TERMINAL DOMAINS; CELL-CELL CONTACTS; IN-VITRO; MADIN-DARBY CANINE KIDNEY CELLS; MASS SPECTROMETRIC ANALYSIS; MDCK CELLS; OCCLUDIN; PHOSPHORYLATION SITES; PLASMA MEMBRANES; RAT-1 CELLS; REASSEMBLY; REVERSIBLE PHOSPHORYLATIONS; STRESS-INDUCED; TIGHT JUNCTIONS; TYROSINE RESIDUES; WILD TYPES;

AMINO ACIDS; ANIMAL CELL CULTURE; CALCIUM; CELL MEMBRANES; CHEMICAL REACTIONS; HYDROGEN; HYDROGEN PEROXIDE; LIVING SYSTEMS STUDIES; PLANTS (BOTANY);

PHOSPHORYLATION;

CALCIUM; HYDROGEN PEROXIDE; MUTANT PROTEIN; OCCLUDIN; PROTEIN ZO1; TYROSINE;

ANIMAL CELL; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL INTERACTION; CELL MEMBRANE; CELL STRAIN; CELL STRAIN CACO 2; CELL STRAIN RAT 1; CHICKEN; CONTROLLED STUDY; GENE DELETION; GENE MUTATION; HUMAN; KIDNEY CELL; MASS SPECTROMETRY; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE SRC; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; RAT; STRAIN DIFFERENCE; TIGHT JUNCTION; WILD TYPE;

ANIMALS; CACO-2 CELLS; CHICKENS; DOGS; HUMANS; HYDROGEN PEROXIDE; MASS SPECTROMETRY; MEMBRANE PROTEINS; MUTATION, MISSENSE; OXIDANTS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; RATS; TIGHT JUNCTIONS; TYROSINE;

RATTUS;

EID: 59449086585     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M804783200     Document Type: Article

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