Colony-stimulating factor 1 receptor blockade prevents fractionated whole-brain irradiation-induced memory deficits

Journal of Neuroinflammation

Volumn 13, Issue 1, 2016, Pages

  Feng, Xi ^a   Jopson, Timothy D ^a   Paladini, Maria Serena ^a   Liu, Sharon ^b   West, Brian L ^c   Gupta, Nalin ^b   Rosi, Susanna ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c PLEXXIKON INC   (United States)

Author keywords

Cognition; CSF 1R; Whole brain irradiation

Indexed keywords

COLONY STIMULATING FACTOR 1 RECEPTOR; COLONY STIMULATING FACTOR RECEPTOR; PLX 5622; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; 5-((5-CHLORO-1H-PYRROLO(2,3-B)PYRIDIN-3-YL)METHYL)-N-((6-(TRIFLUOROMETHYL)PYRIDIN-3-YL)METHYL)PYRIDIN-2-AMINE; AMINOPYRIDINE DERIVATIVE; PYRROLE DERIVATIVE;

ADULT; AMNESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BRAIN RADIATION; CELL COUNT; CELL FUNCTION; CELL LOSS; CLINICAL EFFECTIVENESS; COGNITION; CONTROLLED STUDY; DENDRITIC SPINE; DIET SUPPLEMENTATION; FLOW CYTOMETRY; GOLGI STAIN; MAZE TEST; METRIC DISTANCE TEST; MICROGLIA; MONOCYTE; MOUSE; NEUROLOGIC EXAMINATION; NEUROPROTECTION; NONHUMAN; NOVEL OBJECT RECOGNITION TEST; RADIATION DOSE; RADIATION DOSE FRACTIONATION; RADIATION INJURY; TREATMENT DURATION; YOUNG ADULT; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN; C57BL MOUSE; DRUG EFFECTS; MALE; MEMORY DISORDERS; METABOLISM; RADIATION RESPONSE; TRANSGENIC MOUSE;

AMINOPYRIDINES; ANIMALS; BRAIN; MALE; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PYRROLES; RADIATION EFFECTS; RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR;

EID: 84984608977     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-016-0671-y     Document Type: Article

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