Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation

Cell

Volumn 166, Issue 5, 2016, Pages 1198-1214.e24

  Scott, Daniel C ^a   Rhee, David Y ^b   Duda, David M ^a   Kelsall, Ian R ^c   Olszewski, Jennifer L ^a   Paulo, Joao A ^b   de Jong, Annemieke ^d   Ovaa, Huib ^d,e   Alpi, Arno F ^c   Harper, J Wade ^b   Schulman, Brenda A ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MRC Protein Phosphorylation Unit   (United Kingdom)

^d NETHERLANDS CANCER INSTITUTE   (Netherlands)

^e LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARIH1 PROTEIN; F BOX PROTEIN; PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; ARIH1 PROTEIN, HUMAN; CARRIER PROTEIN; CUL3 PROTEIN, HUMAN; CULL-RING LIGASE, HUMAN; CULLIN; NEDD8 PROTEIN, HUMAN; POLYUBIQUITIN; RBX1 PROTEIN, HUMAN; SEC13 PROTEIN, HUMAN; UBE2L3 PROTEIN, HUMAN; UBIQUITIN; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN PROTEIN LIGASE;

ANTIGEN ANTIBODY COMPLEX; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DIVISION; CELL PROLIFERATION; CONFORMATIONAL TRANSITION; CONJUGATION; CONTROLLED STUDY; COVALENT BOND; GENE SILENCING; IN VIVO STUDY; NEDDYLATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN HOMEOSTASIS; PROTEIN SYNTHESIS INHIBITION; PROTEIN SYNTHESIS REGULATION; PROTEOMICS; REACTION ANALYSIS; STOICHIOMETRY; TRANSCRIPTION ELONGATION; UBIQUITINATION; WILD TYPE; ENZYME SPECIFICITY; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; MUTATION;

CARRIER PROTEINS; CULLIN PROTEINS; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HUMANS; MUTATION; POLYUBIQUITIN; PROTEOMICS; SUBSTRATE SPECIFICITY; UBIQUITIN; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; UBIQUITINS;

EID: 84983786174     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.07.027     Document Type: Article

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