-
1
-
-
84858124845
-
Generation and physiological roles of linear ubiquitin chains
-
Walczak, H., Iwai, K.&Dikic, I. Generation and physiological roles of linear ubiquitin chains. BMC Biol. 10, 23 (2012).
-
(2012)
BMC Biol.
, vol.10
, pp. 23
-
-
Walczak, H.1
Iwai, K.2
Dikic, I.3
-
2
-
-
59649103156
-
Involvement of linear polyubiquitylation of NEMO in NF-kB activation
-
Tokunaga, F. et al. Involvement of linear polyubiquitylation of NEMO in NF-kB activation. Nature Cell Biol. 11, 123-132 (2009).
-
(2009)
Nature Cell Biol
, vol.11
, pp. 123-132
-
-
Tokunaga, F.1
-
3
-
-
79953239980
-
SHARPIN forms a linear ubiquitin ligase complex regulating NF-kB activity and apoptosis
-
Ikeda, F. et al. SHARPIN forms a linear ubiquitin ligase complex regulating NF-kB activity and apoptosis. Nature 471, 637-641 (2011).
-
(2011)
Nature
, vol.471
, pp. 637-641
-
-
Ikeda, F.1
-
4
-
-
79953237668
-
SHARPIN is a component of the NF-kB-activating linear ubiquitin chain assembly complex
-
Tokunaga, F. et al. SHARPIN is a component of the NF-kB-activating linear ubiquitin chain assembly complex. Nature 471, 633-636 (2011).
-
(2011)
Nature
, vol.471
, pp. 633-636
-
-
Tokunaga, F.1
-
5
-
-
79953240109
-
Linear ubiquitination prevents inflammation and regulates immune signalling
-
Gerlach, B. et al. Linear ubiquitination prevents inflammation and regulates immune signalling. Nature 471, 591-596 (2011).
-
(2011)
Nature
, vol.471
, pp. 591-596
-
-
Gerlach, B.1
-
6
-
-
33750219981
-
A ubiquitin ligase complex assembles linear polyubiquitin chains
-
Kirisako, T. et al. A ubiquitin ligase complex assembles linear polyubiquitin chains. EMBO J. 25, 4877-4887 (2006).
-
(2006)
EMBO J
, vol.25
, pp. 4877-4887
-
-
Kirisako, T.1
-
7
-
-
79957949190
-
UBCH7 reactivity profile reveals Parkin and HHARI to be RING/HECT hybrids
-
Wenzel, D. M., Lissounov, A., Brzovic, P. S. & Klevit, R. E. UBCH7 reactivity profile reveals Parkin and HHARI to be RING/HECT hybrids. Nature 474, 105-108 (2011).
-
(2011)
Nature
, vol.474
, pp. 105-108
-
-
Wenzel, D.M.1
Lissounov, A.2
Brzovic, P.S.3
Klevit, R.E.4
-
8
-
-
8844237615
-
Polyubiquitin chains: Polymeric protein signals
-
Pickart, C. M. & Fushman, D. Polyubiquitin chains: polymeric protein signals. Curr. Opin. Chem. Biol. 8, 610-616 (2004).
-
(2004)
Curr. Opin. Chem. Biol
, vol.8
, pp. 610-616
-
-
Pickart, C.M.1
Fushman, D.2
-
10
-
-
0028907874
-
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase
-
Huibregtse, J. M., Scheffner, M., Beaudenon, S. & Howley, P. M. A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc. Natl Acad. Sci. USA 92, 2563-2567 (1995).
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 2563-2567
-
-
Huibregtse, J.M.1
Scheffner, M.2
Beaudenon, S.3
Howley, P.M.4
-
11
-
-
29244447753
-
Different HECT domain ubiquitin ligases employ distinct mechanisms of polyubiquitin chain synthesis
-
Wang, M. & Pickart, C. M. Different HECT domain ubiquitin ligases employ distinct mechanisms of polyubiquitin chain synthesis. EMBO J. 24, 4324-4333 (2005).
-
(2005)
EMBO J
, vol.24
, pp. 4324-4333
-
-
Wang, M.1
Pickart, C.M.2
-
12
-
-
34250162899
-
The ring between ring fingers (RBR) protein family
-
Eisenhaber, B., Chumak, N., Eisenhaber, F. & Hauser, M. T. The ring between ring fingers (RBR) protein family. Genome Biol. 8, 209 (2007).
-
(2007)
Genome Biol
, vol.8
, pp. 209
-
-
Eisenhaber, B.1
Chumak, N.2
Eisenhaber, F.3
Hauser, M.T.4
-
13
-
-
84858135252
-
Following Ariadne's thread: A new perspective on RBR ubiquitin ligases
-
Wenzel, D. M. & Klevit, R. E. Following Ariadne's thread: a new perspective on RBR ubiquitin ligases. BMC Biol. 10, 24 (2012).
-
(2012)
BMC Biol
, vol.10
, pp. 24
-
-
Wenzel, D.M.1
Klevit, R.E.2
-
14
-
-
84865709638
-
LUBA csynthesizes linear ubiquitin chains via a thioester intermediate
-
Stieglitz, B., Morris-Davies, A. C., Koliopoulos, M. G., Christodoulou, E.& Rittinger, K. LUBACsynthesizes linear ubiquitin chains via a thioester intermediate.EMBORep. 13, 840-846 (2012).
-
(2012)
EMBO Rep
, vol.13
, pp. 840-846
-
-
Stieglitz, B.1
Morris-Davies, A.C.2
Koliopoulos, M.G.3
Christodoulou, E.4
Rittinger, K.5
-
15
-
-
84867096523
-
The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension
-
Smit, J. J. et al. The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension. EMBO J. 31, 3833-3844 (2012).
-
(2012)
EMBO J
, vol.31
, pp. 3833-3844
-
-
Smit, J.J.1
-
16
-
-
84879251778
-
Structure of Parkin reveals mechanisms for ubiquitin ligase activation
-
Trempe, J. F. et al. Structure of Parkin reveals mechanisms for ubiquitin ligase activation. Science 340, 1451-1455 (2013).
-
(2013)
Science
, vol.340
, pp. 1451-1455
-
-
Trempe, J.F.1
-
17
-
-
84881477223
-
Structure of the human Parkin ligase domain in an autoinhibited state
-
Wauer, T. & Komander, D. Structure of the human Parkin ligase domain in an autoinhibited state. EMBO J. 32, 2099-2112 (2013).
-
(2013)
EMBO J
, vol.32
, pp. 2099-2112
-
-
Wauer, T.1
Komander, D.2
-
18
-
-
84879980089
-
A molecular explanation for the recessive nature of Parkin-linked Parkinson's disease
-
Spratt, D. E. et al. A molecular explanation for the recessive nature of Parkin-linked Parkinson's disease. Nature Commun. 4, 1983, http://dx.doi.org/10. 1038/ ncomms2983 (2013).
-
(2013)
Nature Commun
, vol.4
, pp. 1983
-
-
Spratt, D.E.1
-
19
-
-
84879674444
-
Structure and function of Parkin E3ubiquitin ligase reveals aspects of RING and HECT ligases
-
Riley, B. E. et al. Structure and function of Parkin E3ubiquitin ligase reveals aspects of RING and HECT ligases. Nature Commun. 4, 1982, http://dx.doi.org/10.1038/ ncomms2982 (2013).
-
(2013)
Nature Commun
, vol.4
, pp. 1982
-
-
Riley, B.E.1
-
20
-
-
84878840303
-
Structure of HHARI, a RING-IBR-RING ubiquitin ligase: Autoinhibition of an Ariadne-family E3 and insights into ligation mechanism
-
Duda, D. M. et al. Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism. Structure 21, 1030-1041 (2013).
-
(2013)
Structure
, vol.21
, pp. 1030-1041
-
-
Duda, D.M.1
-
21
-
-
33847688139
-
Structure of the Parkin in-between-ring domain provides insights for E3-ligase dysfunction in autosomal recessive Parkinson's disease
-
Beasley, S. A., Hristova, V. A. & Shaw, G. S. Structure of the Parkin in-between-ring domain provides insights for E3-ligase dysfunction in autosomal recessive Parkinson's disease. Proc. Natl Acad. Sci. USA 104, 3095-3100 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 3095-3100
-
-
Beasley, S.A.1
Hristova, V.A.2
Shaw, G.S.3
-
22
-
-
33744911377
-
Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway
-
Yunus, A. A. & Lima, C. D. Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway. Nature Struct. Mol. Biol. 13, 491-499 (2006).
-
(2006)
Nature Struct. Mol. Biol
, vol.13
, pp. 491-499
-
-
Yunus, A.A.1
Lima, C.D.2
-
23
-
-
0141753130
-
A conserved catalytic residue in the ubiquitin-conjugating enzyme family
-
Wu, P. Y. et al. A conserved catalytic residue in the ubiquitin-conjugating enzyme family. EMBO J. 22, 5241-5250 (2003).
-
(2003)
EMBO J
, vol.22
, pp. 5241-5250
-
-
Wu, P.Y.1
-
24
-
-
79952290609
-
The mechanismof linkage-specific ubiquitin chain elongation by a single-subunit E2
-
Wickliffe, K. E., Lorenz, S., Wemmer, D. E., Kuriyan, J. & Rape, M. The mechanismof linkage-specific ubiquitin chain elongation by a single-subunit E2. Cell 144, 769-781 (2011).
-
(2011)
Cell
, vol.144
, pp. 769-781
-
-
Wickliffe, K.E.1
Lorenz, S.2
Wemmer, D.E.3
Kuriyan, J.4
Rape, M.5
-
25
-
-
33749506057
-
Mms2- Ubc13 covalently bound to ubiquitin reveals the structural basis of linkagespecific polyubiquitin chain formation
-
Eddins, M. J., Carlile, C. M., Gomez, K. M., Pickart, C. M. & Wolberger, C. Mms2- Ubc13 covalently bound to ubiquitin reveals the structural basis of linkagespecific polyubiquitin chain formation. Nature Struct. Mol. Biol. 13, 915-920 (2006).
-
(2006)
Nature Struct. Mol. Biol
, vol.13
, pp. 915-920
-
-
Eddins, M.J.1
Carlile, C.M.2
Gomez, K.M.3
Pickart, C.M.4
Wolberger, C.5
-
26
-
-
28944435024
-
Mechanism of lysine 48-linked ubiquitin-chain synthesis by the cullin-RING ubiquitin-ligase complex SCF-Cdc34
-
Petroski, M. D. & Deshaies, R. J. Mechanism of lysine 48-linked ubiquitin-chain synthesis by the cullin-RING ubiquitin-ligase complex SCF-Cdc34. Cell 123, 1107-1120 (2005).
-
(2005)
Cell
, vol.123
, pp. 1107-1120
-
-
Petroski, M.D.1
Deshaies, R.J.2
-
27
-
-
0023684064
-
A general method of in vitro preparation and specific mutagenesis of DNA fragments: Study of protein and DNA interactions
-
Higuchi, R., Krummel, B. & Saiki, R. K. A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions. Nucleic Acids Res. 16, 7351-7367 (1988).
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 7351-7367
-
-
Higuchi, R.1
Krummel, B.2
Saiki, R.K.3
-
30
-
-
76449098262
-
PHENIX: A comprehensive Python-based system for macromolecular structure solution
-
Adams, P. D. et al. PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr. D 66, 213-221 (2010).
-
(2010)
Acta Crystallogr D
, vol.66
, pp. 213-221
-
-
Adams, P.D.1
-
31
-
-
34447508216
-
Phaser crystallographic software
-
McCoy, A. J. et al.Phaser crystallographic software. J.Appl. Crystallogr.40, 658-674 (2007).
-
(2007)
J.Appl. Crystallogr.
, vol.40
, pp. 658-674
-
-
McCoy, A.J.1
-
32
-
-
13244281317
-
Coot: Model-building tools for molecular graphics
-
Emsley, P. & Cowtan, K. Coot: model-building tools for molecular graphics. Acta Crystallogr. D 60, 2126-2132 (2004).
-
(2004)
Acta Crystallogr D
, vol.60
, pp. 2126-2132
-
-
Emsley, P.1
Cowtan, K.2
-
33
-
-
0030924992
-
Refinement of macromolecular structures by the maximum-likelihood method
-
Murshudov, G. N., Vagin, A. A. & Dodson, E. J. Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr. D 53, 240-255 (1997).
-
(1997)
Acta Crystallogr D
, vol.53
, pp. 240-255
-
-
Murshudov, G.N.1
Vagin, A.A.2
Dodson, E.J.3
-
34
-
-
33744809773
-
Macromolecular size-and-shape distributions by sedimentation velocity analytical ultracentrifugation
-
Brown, P. H. & Schuck, P. Macromolecular size-and-shape distributions by sedimentation velocity analytical ultracentrifugation. Biophys. J. 90, 4651-4661 (2006).
-
(2006)
Biophys. J
, vol.90
, pp. 4651-4661
-
-
Brown, P.H.1
Schuck, P.2
-
35
-
-
84865781586
-
Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis
-
Plechanovova, A., Jaffray, E. G., Tatham, M. H., Naismith, J. H. & Hay, R. T. Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis. Nature 489, 115-120 (2012).
-
(2012)
Nature
, vol.489
, pp. 115-120
-
-
Plechanovova, A.1
Jaffray, E.G.2
Tatham, M.H.3
Naismith, J.H.4
Hay, R.T.5
-
36
-
-
84866124869
-
BIRC7-E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimmer
-
Dou, H., Buetow, L., Sibbet, G. J., Cameron, K. & Huang, D. T. BIRC7-E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer. Nature Struct. Mol. Biol. 19, 876-883 (2012).
-
(2012)
Nature Struct. Mol. Biol
, vol.19
, pp. 876-883
-
-
Dou, H.1
Buetow, L.2
Sibbet, G.J.3
Cameron, K.4
Huang, D.T.5
-
37
-
-
84866858702
-
Structure of an E3:E2,Ub complex reveals an allosteric mechanism shared among RING/U-box ligases
-
Pruneda, J. N. et al. Structure of an E3:E2,Ub complex reveals an allosteric mechanism shared among RING/U-box ligases. Mol. Cell 47, 933-942 (2012).
-
(2012)
Mol. Cell
, vol.47
, pp. 933-942
-
-
Pruneda, J.N.1
|