Gln40 deamidation blocks structural reconfiguration and activation of SCF ubiquitin ligase complex by Nedd8

Nature Communications

Volumn 6, Issue , 2015, Pages

  Yu, Clinton ^a   Mao, Haibin ^b   Novitsky, Eric J ^c   Tang, Xiaobo ^b   Rychnovsky, Scott D ^c   Zheng, Ning ^b   Huang, Lan ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYPTOCHROME 2; CULLIN; CULLIN 1; GLUTAMIC ACID DERIVATIVE; GLUTAMINE; GLUTAMINE 40; LYSINE; NEDD8 PROTEIN; RING BOX PROTEIN 1; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CARRIER PROTEIN; CULL-RING LIGASE, HUMAN; GLUTAMIC ACID; NEDD8 PROTEIN, HUMAN; PROTEIN BINDING; RBX1 PROTEIN, HUMAN; UBIQUITIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL FUNCTION; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DEAMINATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME STABILITY; ENZYME STRUCTURE; GENETIC LINKAGE; HUMAN; IN VITRO STUDY; MASS SPECTROMETRY; MOLECULAR WEIGHT; NEDDYLATION; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN CROSS LINKING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; RING FINGER MOTIF; SOLUBILITY; UBIQUITINATION; CHEMISTRY; ENZYME ACTIVE SITE; GENETICS; METABOLISM; PROTEIN MOTIF;

BACTERIA (MICROORGANISMS);

AMINO ACID MOTIFS; CARRIER PROTEINS; CATALYTIC DOMAIN; CULLIN PROTEINS; DEAMINATION; GLUTAMIC ACID; GLUTAMINE; HUMANS; MASS SPECTROMETRY; PROTEIN BINDING; SKP CULLIN F-BOX PROTEIN LIGASES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINS;

EID: 84949293487     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10053     Document Type: Article

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