5-Aminolevulinic acid coated microneedles for photodynamic therapy of skin tumors

Journal of Controlled Release

Volumn 239, Issue , 2016, Pages 72-81

  Jain, Amit K ^a   Lee, Chang Hyun ^a   Gill, Harvinder S ^a  

^a Texas Tech University   (United States)

Author keywords

5 ALA; Coated microneedles; Photobleaching; Photodynamic therapy; PPIX; Skin cancer

Indexed keywords

COATINGS; EFFICIENCY; NEEDLES; PHOTOBLEACHING; PHOTOSENSITIZERS; SCANNING ELECTRON MICROSCOPY; TUMORS;

5-ALA; 5-AMINOLEVULINIC ACID; 5-AMINOLEVULINIC ACID (5-ALA); MICRONEEDLE PATCHES; MICRONEEDLES; PPIX; SKIN CANCERS; TOPICAL APPLICATION;

PHOTODYNAMIC THERAPY;

AMINOLEVULINIC ACID; CRYSTAL VIOLET; PROTOPORPHYRIN; PHOTOSENSITIZING AGENT;

ACTINIC KERATOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; BASAL CELL CARCINOMA; BLEACHING; CADAVER; CONFOCAL LASER SCANNING MICROSCOPY; CONTROLLED STUDY; CREAM; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFICACY; EXPERIMENTAL PIG; FEMALE; MAXIMUM PLASMA CONCENTRATION; MICRONEEDLE; MOUSE; NONHUMAN; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; RED LIGHT; SCANNING ELECTRON MICROSCOPY; SKIN PENETRATION; SKIN SURFACE; SKIN TUMOR; SKINFOLD THICKNESS; STRATUM CORNEUM; SURFACE TENSION; TIME TO MAXIMUM PLASMA CONCENTRATION; TUMOR GROWTH; TUMOR VOLUME; VISCOSITY; ANIMAL; BAGG ALBINO MOUSE; CUTANEOUS DRUG ADMINISTRATION; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; MICROINJECTION; NEEDLE; PHOTOCHEMOTHERAPY; PHYSIOLOGY; PIG; PROCEDURES; SKIN ABSORPTION;

ADMINISTRATION, CUTANEOUS; AMINOLEVULINIC ACID; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MICE; MICE, INBRED BALB C; MICROINJECTIONS; NEEDLES; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; SKIN ABSORPTION; SKIN NEOPLASMS; SWINE;

EID: 84983489045     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2016.08.015     Document Type: Article

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