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Volumn 115, Issue 6, 2016, Pages 3217-3228

Development of a spontaneously active dorsal root ganglia assay using multiwell multielectrode arrays

Author keywords

DRG; MEA; Nociceptors; Sensory; Spontaneous activity

Indexed keywords

BRADYKININ; CALCIUM CHANNEL BLOCKING AGENT; CAPSAICIN; POTASSIUM CHANNEL BLOCKING AGENT; SODIUM CHANNEL BLOCKING AGENT; TACHYKININ RECEPTOR ANTAGONIST; AGENTS ACTING ON THE PERIPHERAL NERVOUS AND NEUROMUSCULAR SYSTEMS; AGENTS AFFECTING WATER, MOLECULE OR ION TRANSPORT; MIBEFRADIL; SODIUM CHLORIDE; SUBSTANCE P; TETRODOTOXIN;

EID: 84983293834     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.01122.2015     Document Type: Article
Times cited : (39)

References (55)
  • 1
    • 0030730929 scopus 로고    scopus 로고
    • 2+ channel current in rat sensory neurons by a G-protein-independent mechanism
    • 2+ channel current in rat sensory neurons by a G-protein-independent mechanism. J Neurosci 17, 8721-8728, 1997.
    • (1997) J Neurosci , vol.17 , pp. 8721-8728
    • Abdulla, F.A.1    Smith, P.A.2
  • 2
    • 84862494075 scopus 로고    scopus 로고
    • Analgesic antidepressants promote the responsiveness of locus coeruleus neurons to noxious stimulation: Implications for neuropathic pain
    • Alba-Delgado C, Mico JA, Sanchez-Blazquez P, Berrocoso E. Analgesic antidepressants promote the responsiveness of locus coeruleus neurons to noxious stimulation: implications for neuropathic pain. Pain 153, 1438-1449, 2012.
    • (2012) Pain , vol.153 , pp. 1438-1449
    • Alba-Delgado, C.1    Mico, J.A.2    Sanchez-Blazquez, P.3    Berrocoso, E.4
  • 3
    • 80053337076 scopus 로고    scopus 로고
    • Predictive validity of behavioural animal models for chronic pain
    • Berge OG. Predictive validity of behavioural animal models for chronic pain. Br J Pharmacol 164, 1195-1206, 2011.
    • (2011) Br J Pharmacol , vol.164 , pp. 1195-1206
    • Berge, O.G.1
  • 4
    • 0029094144 scopus 로고
    • Voltage-dependent blockade of diverse types of voltage-gated Ca2+ channels expressed in Xenopus oocytes by the Ca2+ channel antagonist mibefradil (Ro 40-5967)
    • Bezprozvanny I, Tsien RW. Voltage-dependent blockade of diverse types of voltage-gated Ca2+ channels expressed in Xenopus oocytes by the Ca2+ channel antagonist mibefradil (Ro 40-5967). Mol Pharmacol 48, 540-549, 1995.
    • (1995) Mol Pharmacol , vol.48 , pp. 540-549
    • Bezprozvanny, I.1    Tsien, R.W.2
  • 5
    • 0030434482 scopus 로고    scopus 로고
    • Selective N-type neuronal voltage-sensitive calcium channel blocker, SNX-111, produces spinal antinociception in rat models of acute, persistent and neuropathic pain
    • Bowersox SS, Gadbois T, Singh T, Pettus M, Wang YX, Luther RR. Selective N-type neuronal voltage-sensitive calcium channel blocker, SNX-111, produces spinal antinociception in rat models of acute, persistent and neuropathic pain. J Pharmacol Exp Ther 279, 1243-1249, 1996.
    • (1996) J Pharmacol Exp Ther , vol.279 , pp. 1243-1249
    • Bowersox, S.S.1    Gadbois, T.2    Singh, T.3    Pettus, M.4    Wang, Y.X.5    Luther, R.R.6
  • 8
    • 0031466388 scopus 로고    scopus 로고
    • Discovery and main pharmacological properties of mibefradil (Ro 40-5967), the first selective T-type calcium channel blocker
    • Clozel JP, Ertel EA, Ertel SI. Discovery and main pharmacological properties of mibefradil (Ro 40-5967), the first selective T-type calcium channel blocker. J Hypertens Suppl 15, S17-S25, 1997.
    • (1997) J Hypertens Suppl , vol.15 , pp. S17-S25
    • Clozel, J.P.1    Ertel, E.A.2    Ertel, S.I.3
  • 9
    • 84931275481 scopus 로고    scopus 로고
    • Persistent hindlimb inflammation induces changes in activation properties of hyperpolarization-activated current (Ih) in rat C-fiber nociceptors in vivo
    • Djouhri L, Al Otaibi M, Kahlat K, Smith T, Sathish J, Weng X. Persistent hindlimb inflammation induces changes in activation properties of hyperpolarization-activated current (Ih) in rat C-fiber nociceptors in vivo. Neuroscience 301, 121-133, 2015.
    • (2015) Neuroscience , vol.301 , pp. 121-133
    • Djouhri, L.1    Al Otaibi, M.2    Kahlat, K.3    Smith, T.4    Sathish, J.5    Weng, X.6
  • 10
    • 32644440589 scopus 로고    scopus 로고
    • Spontaneous pain, both neuropathic and inflammatory, is related to frequency of spontaneous firing in intact C-fiber nociceptors
    • Djouhri L, Koutsikou S, Fang X, McMullan S, Lawson SN. Spontaneous pain, both neuropathic and inflammatory, is related to frequency of spontaneous firing in intact C-fiber nociceptors. J Neurosci 26, 1281-1292, 2006.
    • (2006) J Neurosci , vol.26 , pp. 1281-1292
    • Djouhri, L.1    Koutsikou, S.2    Fang, X.3    McMullan, S.4    Lawson, S.N.5
  • 11
    • 0034648706 scopus 로고    scopus 로고
    • Nerve growth factor maintains potassium conductance after nerve injury in adult cutaneous afferent dorsal root ganglion neurons
    • Everill B, Kocsis JD. Nerve growth factor maintains potassium conductance after nerve injury in adult cutaneous afferent dorsal root ganglion neurons. Neuroscience 100, 417-422, 2000.
    • (2000) Neuroscience , vol.100 , pp. 417-422
    • Everill, B.1    Kocsis, J.D.2
  • 12
    • 33846924993 scopus 로고    scopus 로고
    • A nonparametric approach for detection of bursts in spike trains
    • Gourevitch B, Eggermont JJ. A nonparametric approach for detection of bursts in spike trains. J Neurosci Methods 160, 349-358, 2007.
    • (2007) J Neurosci Methods , vol.160 , pp. 349-358
    • Gourevitch, B.1    Eggermont, J.J.2
  • 13
    • 58549085757 scopus 로고    scopus 로고
    • Antinociceptive effects of the marine snail peptides conantokin-G and conotoxin MVIIA alone and in combination in rat models of pain
    • Hama A, Sagen J. Antinociceptive effects of the marine snail peptides conantokin-G and conotoxin MVIIA alone and in combination in rat models of pain. Neuropharmacology 56, 556-563, 2009.
    • (2009) Neuropharmacology , vol.56 , pp. 556-563
    • Hama, A.1    Sagen, J.2
  • 14
    • 1642580583 scopus 로고    scopus 로고
    • Pre-and postsynaptic contributions of voltage-dependent Ca2+ channels to nociceptive transmission in rat spinal lamina I neurons
    • Heinke B, Balzer E, Sandkuhler J. Pre-and postsynaptic contributions of voltage-dependent Ca2+ channels to nociceptive transmission in rat spinal lamina I neurons. Eur J Neurosci 19, 103-111, 2004.
    • (2004) Eur J Neurosci , vol.19 , pp. 103-111
    • Heinke, B.1    Balzer, E.2    Sandkuhler, J.3
  • 16
    • 0030897660 scopus 로고    scopus 로고
    • NGF involvement in pain induced by chronic constriction injury of the rat sciatic nerve
    • Herzberg U, Eliav E, Dorsey JM, Gracely RH, Kopin IJ. NGF involvement in pain induced by chronic constriction injury of the rat sciatic nerve. Neuroreport 8, 1613-1618, 1997.
    • (1997) Neuroreport , vol.8 , pp. 1613-1618
    • Herzberg, U.1    Eliav, E.2    Dorsey, J.M.3    Gracely, R.H.4    Kopin, I.J.5
  • 17
    • 0034214841 scopus 로고    scopus 로고
    • NK1 (substance P) receptor antagonists-why are they not analgesic in humans?
    • Hill R. NK1 (substance P) receptor antagonists-why are they not analgesic in humans? Trends Pharmacol Sci 21: 244-246, 2000.
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 244-246
    • Hill, R.1
  • 18
    • 0020687323 scopus 로고
    • Suppression of noxiously evoked WDR dorsal horn neuronal activity by spinally administered morphine
    • Homma E, Collins JG, Kitahata LM, Matsumoto M, Kawahara M. Suppression of noxiously evoked WDR dorsal horn neuronal activity by spinally administered morphine. Anesthesiology 58, 232-236, 1983.
    • (1983) Anesthesiology , vol.58 , pp. 232-236
    • Homma, E.1    Collins, J.G.2    Kitahata, L.M.3    Matsumoto, M.4    Kawahara, M.5
  • 19
    • 0029917477 scopus 로고    scopus 로고
    • Low-threshold calcium currents in central nervous system neurons
    • Huguenard JR. Low-threshold calcium currents in central nervous system neurons. Annu Rev Physiol 58, 329-348, 1996.
    • (1996) Annu Rev Physiol , vol.58 , pp. 329-348
    • Huguenard, J.R.1
  • 21
    • 33745369483 scopus 로고    scopus 로고
    • The role of peripheral T-type calcium channels in pain transmission
    • Jevtovic-Todorovic V, Todorovic SM. The role of peripheral T-type calcium channels in pain transmission. Cell Calcium 40, 197-203, 2006.
    • (2006) Cell Calcium , vol.40 , pp. 197-203
    • Jevtovic-Todorovic, V.1    Todorovic, S.M.2
  • 22
    • 0026572227 scopus 로고
    • Spontaneous discharge originates in the dorsal root ganglion at the onset of a painful peripheral neuropathy in the rat
    • Kajander KC, Wakisaka S, Bennett GJ. Spontaneous discharge originates in the dorsal root ganglion at the onset of a painful peripheral neuropathy in the rat. Neurosci Lett 138, 225-228, 1992.
    • (1992) Neurosci Lett , vol.138 , pp. 225-228
    • Kajander, K.C.1    Wakisaka, S.2    Bennett, G.J.3
  • 23
    • 84891119753 scopus 로고    scopus 로고
    • Chronic NGF treatment induces somatic hyperexcitability in cultured dorsal root ganglion neurons of the rat
    • Kayano T, Kitamura N, Moriya T, Kuwahara T, Komagiri Y, Toescu EC, Shibuya I. Chronic NGF treatment induces somatic hyperexcitability in cultured dorsal root ganglion neurons of the rat. Biomed Res 34, 329-342, 2013.
    • (2013) Biomed Res , vol.34 , pp. 329-342
    • Kayano, T.1    Kitamura, N.2    Moriya, T.3    Kuwahara, T.4    Komagiri, Y.5    Toescu, E.C.6    Shibuya, I.7
  • 24
    • 27244461208 scopus 로고    scopus 로고
    • Nerve growth factorinduced hyperexcitability of rat sensory neuron in culture
    • Kitamura N, Konno A, Kuwahara T, Komagiri Y. Nerve growth factorinduced hyperexcitability of rat sensory neuron in culture. Biomed Res 26, 123-130, 2005.
    • (2005) Biomed Res , vol.26 , pp. 123-130
    • Kitamura, N.1    Konno, A.2    Kuwahara, T.3    Komagiri, Y.4
  • 25
    • 0032795085 scopus 로고    scopus 로고
    • Nickel block of three cloned T-type calcium channels: Low concentrations selectively block alpha1H
    • Lee JH, Gomora JC, Cribbs LL, Perez-Reyes E. Nickel block of three cloned T-type calcium channels: low concentrations selectively block alpha1H. Biophys J 77, 3034-3042, 1999.
    • (1999) Biophys J , vol.77 , pp. 3034-3042
    • Lee, J.H.1    Gomora, J.C.2    Cribbs, L.L.3    Perez-Reyes, E.4
  • 26
    • 84875677048 scopus 로고    scopus 로고
    • An efficient method for dorsal root ganglia neurons purification with a one-time anti-mitotic reagent treatment
    • Liu R, Lin G, Xu H. An efficient method for dorsal root ganglia neurons purification with a one-time anti-mitotic reagent treatment. PLoS One 8, e60558, 2013.
    • (2013) PLoS One , vol.8
    • Liu, R.1    Lin, G.2    Xu, H.3
  • 27
    • 38449115965 scopus 로고    scopus 로고
    • Multiple sites for generation of ectopic spontaneous activity in neurons of the chronically compressed dorsal root ganglion
    • Ma C, LaMotte RH. Multiple sites for generation of ectopic spontaneous activity in neurons of the chronically compressed dorsal root ganglion. J Neurosci 27, 14059-14068, 2007.
    • (2007) J Neurosci , vol.27 , pp. 14059-14068
    • Ma, C.1    LaMotte, R.H.2
  • 29
    • 84926357240 scopus 로고    scopus 로고
    • In vitro studies of neuronal networks and synaptic plasticity in invertebrates and in mammals using multielectrode arrays
    • Massobrio P, Tessadori J, Chiappalone M, Ghirardi M. In vitro studies of neuronal networks and synaptic plasticity in invertebrates and in mammals using multielectrode arrays. Neural Plast 2015, 196195, 2015.
    • (2015) Neural Plast , vol.2015 , pp. 196195
    • Massobrio, P.1    Tessadori, J.2    Chiappalone, M.3    Ghirardi, M.4
  • 30
    • 84867233159 scopus 로고    scopus 로고
    • Evaluation of multi-well microelectrode arrays for neurotoxicity screening using a chemical training set
    • McConnell ER, McClain MA, Ross J, Lefew WR, Shafer TJ. Evaluation of multi-well microelectrode arrays for neurotoxicity screening using a chemical training set. Neurotoxicology 33, 1048-1057, 2012.
    • (2012) Neurotoxicology , vol.33 , pp. 1048-1057
    • McConnell, E.R.1    McClain, M.A.2    Ross, J.3    Lefew, W.R.4    Shafer, T.J.5
  • 31
    • 0028340076 scopus 로고
    • Selective inhibition of T-type Ca2+ channels by Ro 40-5967
    • Mishra SK, Hermsmeyer K. Selective inhibition of T-type Ca2+ channels by Ro 40-5967. Circ Res 75, 144-148, 1994.
    • (1994) Circ Res , vol.75 , pp. 144-148
    • Mishra, S.K.1    Hermsmeyer, K.2
  • 35
    • 84901419087 scopus 로고    scopus 로고
    • Improving the translation of analgesic drugs to the clinic: Animal models of neuropathic pain
    • Percie du Sert N, Rice AS. Improving the translation of analgesic drugs to the clinic: animal models of neuropathic pain. Br J Pharmacol 171, 2951-2963, 2014.
    • (2014) Br J Pharmacol , vol.171 , pp. 2951-2963
    • Percie du Sert, N.1    Rice, A.S.2
  • 36
    • 0023001913 scopus 로고
    • Multiple calcium channels mediate neurotransmitter release from peripheral neurons
    • Perney MT, Hirning LD, Leeman SE, Miller RJ. Multiple calcium channels mediate neurotransmitter release from peripheral neurons. Proc Natl Acad Sci USA 83, 6656-6659, 1986.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 6656-6659
    • Perney, M.T.1    Hirning, L.D.2    Leeman, S.E.3    Miller, R.J.4
  • 37
    • 3042798891 scopus 로고    scopus 로고
    • The neurobiology of antiepileptic drugs
    • Rogawski MA, Loscher W. The neurobiology of antiepileptic drugs. Nat Rev Neurosci 5, 553-564, 2004.
    • (2004) Nat Rev Neurosci , vol.5 , pp. 553-564
    • Rogawski, M.A.1    Loscher, W.2
  • 38
    • 0030971813 scopus 로고    scopus 로고
    • Phenytoin and carbamazepine: Differential inhibition of sodium currents in small cells from adult rat dorsal root ganglia
    • Rush AM, Elliott JR. Phenytoin and carbamazepine: differential inhibition of sodium currents in small cells from adult rat dorsal root ganglia. Neurosci Lett 226, 95-98, 1997.
    • (1997) Neurosci Lett , vol.226 , pp. 95-98
    • Rush, A.M.1    Elliott, J.R.2
  • 41
    • 0030152343 scopus 로고    scopus 로고
    • Spontaneous action potential activity in isolated dorsal root ganglion neurons from rats with a painful neuropathy
    • Study RE, Kral MG. Spontaneous action potential activity in isolated dorsal root ganglion neurons from rats with a painful neuropathy. Pain 65, 235-242, 1996.
    • (1996) Pain , vol.65 , pp. 235-242
    • Study, R.E.1    Kral, M.G.2
  • 42
    • 0036155045 scopus 로고    scopus 로고
    • Gabapentin inhibits high-threshold calcium channel currents in cultured rat dorsal root ganglion neurones
    • Sutton KG, Martin DJ, Pinnock RD, Lee K, Scott RH. Gabapentin inhibits high-threshold calcium channel currents in cultured rat dorsal root ganglion neurones. Br J Pharmacol 135, 257-265, 2002.
    • (2002) Br J Pharmacol , vol.135 , pp. 257-265
    • Sutton, K.G.1    Martin, D.J.2    Pinnock, R.D.3    Lee, K.4    Scott, R.H.5
  • 43
    • 33845432166 scopus 로고    scopus 로고
    • The role of T-type calcium channels in peripheral and central pain processing
    • Todorovic SM, Jevtovic-Todorovic V. The role of T-type calcium channels in peripheral and central pain processing. CNS Neurol Disord Drug Targets 5, 639-653, 2006.
    • (2006) CNS Neurol Disord Drug Targets , vol.5 , pp. 639-653
    • Todorovic, S.M.1    Jevtovic-Todorovic, V.2
  • 44
    • 0031893944 scopus 로고    scopus 로고
    • Pharmacological properties of T-type Ca2+ current in adult rat sensory neurons: Effects of anticonvulsant and anesthetic agents
    • Todorovic SM, Lingle CJ. Pharmacological properties of T-type Ca2+ current in adult rat sensory neurons: effects of anticonvulsant and anesthetic agents. J Neurophysiol 79, 240-252, 1998.
    • (1998) J Neurophysiol , vol.79 , pp. 240-252
    • Todorovic, S.M.1    Lingle, C.J.2
  • 45
    • 0034406976 scopus 로고    scopus 로고
    • NK1 receptor antagonists-are they really without effect in the pain clinic?
    • author reply 465
    • Urban LA, Fox AJ. NK1 receptor antagonists-are they really without effect in the pain clinic? Trends Pharmacol Sci 21: 462-464; author reply 465, 2000.
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 462-464
    • Urban, L.A.1    Fox, A.J.2
  • 47
    • 77957013000 scopus 로고    scopus 로고
    • Block of neuronal Na+ channels by antidepressant duloxetine in a state-dependent manner
    • Wang SY, Calderon J, Kuo Wang G. Block of neuronal Na+ channels by antidepressant duloxetine in a state-dependent manner. Anesthesiology 113, 655-665, 2010.
    • (2010) Anesthesiology , vol.113 , pp. 655-665
    • Wang, S.Y.1    Calderon, J.2    Kuo Wang, G.3
  • 48
    • 84858706404 scopus 로고    scopus 로고
    • Chronic inflammatory pain is associated with increased excitability and hyperpolarization-activated current (Ih) in C-but not Adelta-nociceptors
    • Weng X, Smith T, Sathish J, Djouhri L. Chronic inflammatory pain is associated with increased excitability and hyperpolarization-activated current (Ih) in C-but not Adelta-nociceptors. Pain 153, 900-914, 2012.
    • (2012) Pain , vol.153 , pp. 900-914
    • Weng, X.1    Smith, T.2    Sathish, J.3    Djouhri, L.4
  • 49
    • 21844463298 scopus 로고    scopus 로고
    • Neuropathic pain: Early spontaneous afferent activity is the trigger
    • Xie W, Strong JA, Meij JT, Zhang JM, Yu L. Neuropathic pain: early spontaneous afferent activity is the trigger. Pain 116, 243-256, 2005.
    • (2005) Pain , vol.116 , pp. 243-256
    • Xie, W.1    Strong, J.A.2    Meij, J.T.3    Zhang, J.M.4    Yu, L.5
  • 50
    • 77957899116 scopus 로고    scopus 로고
    • Increased excitability and spontaneous activity of rat sensory neurons following in vitro stimulation of sympathetic fiber sprouts in the isolated dorsal root ganglion
    • Xie W, Strong JA, Zhang JM. Increased excitability and spontaneous activity of rat sensory neurons following in vitro stimulation of sympathetic fiber sprouts in the isolated dorsal root ganglion. Pain 151, 447-459, 2010.
    • (2010) Pain , vol.151 , pp. 447-459
    • Xie, W.1    Strong, J.A.2    Zhang, J.M.3
  • 51
    • 63449122889 scopus 로고    scopus 로고
    • Gabapentin selectively reduces persistent sodium current in injured type-A dorsal root ganglion neurons
    • Yang RH, Wang WT, Chen JY, Xie RG, Hu SJ. Gabapentin selectively reduces persistent sodium current in injured type-A dorsal root ganglion neurons. Pain 143, 48-55, 2009.
    • (2009) Pain , vol.143 , pp. 48-55
    • Yang, R.H.1    Wang, W.T.2    Chen, J.Y.3    Xie, R.G.4    Hu, S.J.5
  • 52
    • 34748843968 scopus 로고    scopus 로고
    • Regulatory effect of nerve growth factor on release of substance P in cultured dorsal root ganglion neurons of rat
    • Yang XD, Liu Z, Liu HX, Wang LH, Ma CH, Li ZZ. Regulatory effect of nerve growth factor on release of substance P in cultured dorsal root ganglion neurons of rat. Neurosci Bull 23, 215-220, 2007.
    • (2007) Neurosci Bull , vol.23 , pp. 215-220
    • Yang, X.D.1    Liu, Z.2    Liu, H.X.3    Wang, L.H.4    Ma, C.H.5    Li, Z.Z.6
  • 54
    • 14844303990 scopus 로고    scopus 로고
    • A developmental switch in acute sensitization of small dorsal root ganglion (DRG) neurons to capsaicin or noxious heating by NGF
    • Zhu W, Galoyan SM, Petruska JC, Oxford GS, Mendell LM. A developmental switch in acute sensitization of small dorsal root ganglion (DRG) neurons to capsaicin or noxious heating by NGF. J Neurophysiol 92, 3148-3152, 2004.
    • (2004) J Neurophysiol , vol.92 , pp. 3148-3152
    • Zhu, W.1    Galoyan, S.M.2    Petruska, J.C.3    Oxford, G.S.4    Mendell, L.M.5
  • 55
    • 79960652915 scopus 로고    scopus 로고
    • Differential gene expression of neonatal and adult DRG neurons correlates with the differential sensitization of TRPV1 responses to nerve growth factor
    • Zhu W, Oxford GS. Differential gene expression of neonatal and adult DRG neurons correlates with the differential sensitization of TRPV1 responses to nerve growth factor. Neurosci Lett 500, 192-196, 2011.
    • (2011) Neurosci Lett , vol.500 , pp. 192-196
    • Zhu, W.1    Oxford, G.S.2


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