The caffeine-binding adenosine A 2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Batalha, Vânia L ^a,b   Ferreira, Diana G ^a,c,d   Coelho, Joana E ^a   Valadas, Jorge S ^a,o   Gomes, Rui ^a,e   Temido Ferreira, Mariana ^a   Shmidt, Tatiana ^f   Baqi, Younis ^g,h   Buée, Luc ⁱ   Müller, Christa E ^g   Hamdane, Malika ⁱ   Outeiro, Tiago F ^c,j,k   Bader, Michael ^f,l,m   Meijsing, Sebastiaan H ^b   Sadri Vakili, Ghazaleh ⁿ   Blum, David ⁱ   Lopes, Luísa V ^a  

^a UNIVERSITY OF LISBON   (Portugal)

^b MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^c UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^d UNIVERSITY OF PORTO   (Portugal)

^e UNIVERSITY OF LISBON   (Portugal)

^f MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^g UNIVERSITY OF BONN   (Germany)

^h SULTAN QABOOS UNIVERSITY   (Oman)

ⁱ UNIV LILLE   (France)

^j MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^k UniversidadeNova de Lisboa   (Portugal)

^l CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^m UNIVERSITY OF LÜBECK   (Germany)

ⁿ MASSACHUSETTS GENERAL HOSPITAL   (United States)

^o UNIVERSITY OF LEUVEN   (Belgium)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE A2A RECEPTOR; CAFFEINE; CORTICOSTERONE; GLUCOCORTICOID RECEPTOR;

AGING; ANIMAL; ANIMAL MODEL; CELL NUCLEUS; COGNITIVE DEFECT; GENETICS; HUMAN; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MALE; METABOLISM; NERVE CELL PLASTICITY; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT; TRANSGENIC MOUSE;

AGING; ANIMALS; CAFFEINE; CELL NUCLEUS; COGNITIVE DYSFUNCTION; CORTICOSTERONE; HUMANS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; MICE, TRANSGENIC; MODELS, ANIMAL; NEURONAL PLASTICITY; PITUITARY-ADRENAL SYSTEM; RATS; RECEPTOR, ADENOSINE A2A; RECEPTORS, GLUCOCORTICOID;

EID: 84982190182     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep31493     Document Type: Article

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