Adenosine-stimulated adrenal steroidogenesis involves the adenosine A2A and A2B receptors and the Janus kinase 2-mitogen-activated protein kinase kinase-extracellular signal-regulated kinase signaling pathway

International Journal of Biochemistry and Cell Biology

Volumn 40, Issue 12, 2008, Pages 2815-2825

  Chen, Yung Chia ^a   Huang, Shih Horng ^b   Wang, Seu Mei ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b FAR EASTERN MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Adenosine; Adenosine receptor; Signaling pathway; Steroidogenesis

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 6 ETHYL 2 PHENYL 4 PROPYL 3 PYRIDINECARBOXYLIC ACID 5 THIOCARBOXYLIC ACID 5 ETHYL 3 PROPYL ESTER; ADENOSINE; ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR ANTAGONIST; ADENOSINE A2B RECEPTOR; ADENOSINE A2B RECEPTOR ANTAGONIST; ADENOSINE RECEPTOR BLOCKING AGENT; ANTIINFLAMMATORY AGENT; CORTICOSTERONE; CYCLIC AMP BINDING PROTEIN; ENZYME INHIBITOR; JANUS KINASE 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MRS 1706; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PROTEIN SERINE THREONINE KINASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ZM 248315;

ADRENAL CELL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE RELEASE; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; NONHUMAN; PHARMACOLOGICAL BLOCKING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR INTRINSIC ACTIVITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STEROIDOGENESIS;

ADENOSINE; ADRENAL GLANDS; ANIMALS; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; JANUS KINASE 2; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; RATS; RATS, WISTAR; RECEPTOR, ADENOSINE A2A; RECEPTOR, ADENOSINE A2B; STEROIDS;

RATTUS;

EID: 51249124870     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2008.05.016     Document Type: Article

References (38)

1. Aptel H.B., Burnay M.M., Rossier M.F., and Capponi A.M. The role of tyrosine kinases in capacitative calcium influx-mediated aldosterone production in bovine adrenal zona glomerulosa cells. J Endocrinol 163 (1999) 131-138
2. Arai A., Jin A., Yan W., Mizuchi D., Yamamoto K., Nanki T., et al. SDF-1 synergistically enhances IL-3-induced activation of the Raf-1/MEK/Erk signaling pathway through activation of Rac and its effector Pak kinases to promote hematopoiesis and chemotaxis. Cell Signal 17 (2005) 497-506
3. Briscoe J., Guschin D., Rogers N.C., Watling D., Muller M., Horn F., et al. JAKs, STATs and signal transduction in response to the interferons and other cytokines. Philos Trans R Soc Lond B: Biol Sci 351 (1996) 167-171
4. Chen Y.C., Chang M.F., Chen Y., and Wang S.M. Signaling pathways of magnolol-induced adrenal steroidogensis. FEBS Lett 579 (2005) 4337-4343
5. Cooper D.M., and Gleed C. The action of adenosine on steroidogenesis in isolated rat adrenocortical cells. J Steroid Biochem 9 (1978) 973-977
6. Cronstein B.N. Low-dose methotrexate: a mainstay in the treatment of rheumatoid arthritis. Pharmacol Rev 57 (2005) 163-172
7. Feoktistov I., and Biaggioni I. Adenosine A2B receptors. Pharmacol Rev 49 (1997) 381-490
8. Ferreira J.G., Cruz C., Vinson G.P., and Pignatelli D. ACTH modulates ERK phosphorylation in the adrenal gland in a time-dependent manner. Endocr Res 30 (2004) 661-666
9. Fredholm B.B. Adenosine, an endogenous distress signal, modulates tissue damage and repair. Cell Death Differ 14 (2007) 1315-1323
10. Fritz J.D., Swartz D.R., and Greaser M.L. Factors affecting polyacrylamide gel electrophoresis and electroblotting of high molecular-weight myofibrillar protein. Anal Biochem 180 (1989) 205-210
11. Glynn P., and Cooper D.M. Inhibition of bovine adrenocortical adenylate cyclase activity by adenosine. Biochim Biophys Acta 526 (1978) 605-612
12. Ihle J.N. Cytokine receptor signalling. Nature 377 (1995) 591-594
13. Kapas S., Purbrick A., and Hinson J.P. Role of tyrosine kinase and protein kinase C in the steroidogenic actions of angiotensin II, alpha-melanocyte-stimulating hormone and corticotropin in the rat adrenal cortex. Biochem J 305 Pt 2 (1995) 433-438
14. Klinger M., Freissmuth M., and Nanoff C. Adenosine receptors: G protein-mediated signalling and the role of accessory proteins. Cell Signal 14 (2002) 99-108
15. Li J., Feltzer R.E., Dawson K.L., Hudson E.A., and Clark B.J. Janus kinase 2 and calcium are required for angiotensin II-dependent activation of steroidogenic acute regulatory protein transcription in H295R human adrenocortical cells. J Biol Chem 278 (2003) 52355-52362
16. Manna P.R., Chandrala S.P., King S.R., Jo Y., Counis R., Huhtaniemi I.T., et al. Molecular mechanisms of insulin-like growth factor-I mediated regulation of the steroidogenic acute regulatory protein in mouse Leydig cells. Mol Endocrinol 20 (2006) 362-378
17. Manna P.R., Wang X.J., and Stocco D.M. Involvement of multiple transcription factors in the regulation of steroidogenic acute regulatory protein gene expression. Steroids 68 (2003) 1125-1134
18. Montminy M. Transcriptional regulation by cyclic AMP. Annu Rev Biochem 66 (1997) 807-822
19. Mukai K., Mitani F., Shimada H., and Ishimura Y. Involvement of an AP-1 complex in zone-specific expression of the CYP11B1 gene in the rat adrenal cortex. Mol Cell Biol 15 (1995) 6003-6012
20. Ritchie P.K., Spangelo B.L., Krzymowski D.K., Rossiter T.B., Kurth E., and Judd A.M. Adenosine increases interleukin 6 release and decreases tumour necrosis factor release from rat adrenal zona glomerulosa cells, ovarian cells, anterior pituitary cells, and peritoneal macrophages. Cytokine 9 (1997) 187-198
21. Schulte G., and Fredholm B.B. Human adenosine A1, A2A, A2B, and A3 receptors expressed in Chinese hamster ovary cells all mediate the phosphorylation of extracellular-regulated kinase 1/2. Mol Pharmacol 58 (2000) 477-482
22. Schulte G., and Fredholm B.B. The G(s)-coupled adenosine A(2B) receptor recruits divergent pathways to regulate ERK1/2 and p38. Exp Cell Res 290 (2003) 168-176
23. Schulte G., and Fredholm B.B. Signalling from adenosine receptors to mitogen-activated protein kinases. Cell Signal 15 (2003) 813-827
24. Seidel M.G., Klinger M., Freissmuth M., and Holler C. Activation of mitogen-activated protein kinase by the A(2A)-adenosine receptor via a rap1-dependent and via a p21(ras)-dependent pathway. J Biol Chem 274 (1999) 25833-25841
25. Sewer M., and Waterman M. ACTH modulation of transcription factors responsible for steroid hydroxylase gene expression in the adrenal cortex. Microsc Res Tech 61 (2003) 300-307
26. Sexl V., Mancusi G., Holler C., Gloria-Maercker E., Schutz W., and Freissmuth M. Stimulation of the mitogen-activated protein kinase via the A2A-adenosine receptor in primary human endothelial cells. J Biol Chem 272 (1997) 5792-5799
27. Sheng M., Thompson M.A., and Greenberg M.E. CREB: a Ca(2+)-regulated transcription factor phosphorylated by calmodulin-dependent kinases. Science 252 (1991) 1427-1430
28. Sher N., Yivgi-Ohana N., and Orly J. Transcriptional regulation of the P450scc gene (CYP11A1) revisited: binding of GATA, CREB and AP-1 proteins to a distal novel cluster of cis-regulatory elements potentiates AP-2 and SF-1 dependent gene expression in the rodent placenta and ovary. Mol Endocrinol 21 (2007) 948-962
29. Shima S. Inhibition by adenosine of ACTH-stimulated adenylate cyclase and steroidogenesis in the adrenal cortex. Mol Cell Endocrinol 47 (1986) 35-42
30. Sirianni R., Carr B.R., Pezzi V., and Rainey W.E. A role for src tyrosine kinase in regulating adrenal aldosterone production. J Mol Endocrinol 26 (2001) 207-215
31. Wang S.M., Lee L.J., Lin W.W., and Chang C.M. Effects of a water-soluble extract of Cordyceps sinensis on steroidogenesis and capsular morphology of lipid droplets in cultured rat adrenocortical cells. J Cell Biochem 69 (1998) 483-489
32. Wolff J., and Cook G. Activation of steroidogenesis and adenylate cyclase by adenosine in adrenal an Leydig tumor. J Biol Chem 252 (1977) 687-693
33. Wolff J., and Cook G.H. Activation of steroidogenesis and adenylate cyclase by adenosine in adrenal and Leydig tumor cells. J Biol Chem 252 (1977) 687-693
34. Xie H., and Rothstein T.L. Protein kinase C mediates activation of nuclear cAMP response element-binding protein (CREB) in B lymphocytes stimulated through surface Ig. J Immunol 154 (1995) 1717-1723
35. 1 receptors. J Physiol 521 (1999) 81-97
36. Yang E.J., Yoon J.H., and Chung K.C. Bruton's tyrosine kinase phosphorylates cAMP-responsive element-binding protein at serine 133 during neuronal differentiation in immortalized hippocampal progenitor cells. J Biol Chem 279 (2004) 1827-1837
37. Yu R., Hebbar V., Kim D.W., Mandlekar S., Pezzuto J.M., and Kong A.N. Resveratrol inhibits phorbol ester and UV-induced activator protein 1 activation by interfering with mitogen-activated protein kinase pathways. Mol Pharmacol 60 (2001) 217-224
38. Yu R., Wang L., Zhang H., Zhou C., and Zhao Y. Isolation, purification and identification of polysaccharides from cultured Cordyceps militaris. Fitoterapia 75 (2004) 662-666