CaMKII function in the nervous system explored from a genetic perspective

Cold Spring Harbor Symposia on Quantitative Biology

Volumn 61, Issue , 1996, Pages 219-224

  Mayford, M ^a   Bach, M E ^a   Kandel, E ^a  

^a Howard Hughes Medical Institute ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE (CALCIUM,CALMODULIN); ASPARTIC ACID; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE I; DOXYCYCLINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

CALCIUM TRANSPORT; CONFERENCE PAPER; ENZYME ACTIVATION; ENZYME MECHANISM; ENZYME PURIFICATION; LEARNING; LONG TERM POTENTIATION; MEMORY; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; 3' UNTRANSLATED REGION; ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPHOSPHORYLATION; CALCIUM SIGNALING; CONTROLLED STUDY; DNA MODIFICATION; FOREBRAIN; GENE EXPRESSION; GENETIC ANALYSIS; HIPPOCAMPUS; MOUSE; NERVE CELL PLASTICITY; NERVOUS SYSTEM; PROTEIN FUNCTION; TRANSGENIC MOUSE;

EID: 0030440301     PISSN: 00917451     EISSN: None     Source Type: Book Series    
DOI: 10.1101/sqb.1996.061.01.024     Document Type: Conference Paper

References (24)

1. Bach, M.E., R.D. Hawkins, M. Osman, E.R. Kandel, and M. Mayford. 1995. Impairment of spatial but not contextual memory in CaMKII mutant mice with a selective loss of hippocampal LTP in the range of the θ frequency. Cell 81: 905.
2. Bear, M.F. and R.C. Malenka. 1994. Synaptic plasticity: LTP and LTD. Curr. Opin. Neurobiol. 4: 389.
3. Bliss, T.V.P. and G.L. Collingridge. 1993. A synaptic model of memory: Long-term potentiation in the hippocampus. Nature 361: 31.
4. Dudek, S.M. and M.F. Bear. 1993. Bidirectional long-term modification of synaptic effectiveness in the adult and immature hippocampus. J. Neurosci. 13: 2910.
5. 2+/calmodulin-dependent protein kinase II: Mutation of threonine 286 to alanine and aspartate. J. Biol. Chem. 264: 16759.
6. Fujii, S., K. Saito, H. Miyatawa, K. Ito, and H. Kato. 1991. Reversal of long-term potentiation (depotentiation) induced by tetanus stimulation of the input to CA1 neurons of guinea pig hippocampal slices. Brain Res. 555: 112.
7. Furth, P.A., L. St. Onge, H. Boger, P. Gruss, M. Gossen, A. Kistner, H. Bujard, and L. Henninghausen. 1994. Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter. Proc. Natl. Acad. Sci. 91: 9302.
8. Gossen, M. and H. Bujard. 1992. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. 89: 5547.
9. 2+/calmodulin-dependent protein kinases. Annu. Rev. Biochem. 61: 559.
10. Hvalby, O , H.C. Hemmings, O. Paulsen, A.J. Czernik, A.C. Nairn, J.M. Godfraind, V. Jensen, M. Raastad, F. Storm, and P. Andersen. 1994. Specificity of protein kinase inhibitor peptides and induction of long-term potentiation. Proc. Natl. Acad. Sci. 91: 4761.
11. Lisman, J. 1994. The CaM kinase II hypothesis for the storage of synaptic memory. Trends Neurosci. 17: 406.
12. Malenka, R.C., J.A. Kauer, D.J. Ferkel, M.D. Mauk, P.T. Kelly, R.A. Nicoll, and M.N. Waxham. 1989. An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation. Nature 340: 554.
13. Malinow, R., H. Schulman, and R.W. Tsien. 1989. Inhibition of postsynaptic PKC or CaMKII blocks induction but not expression of LTP. Science 245: 862.
14. Mayford, M., J. Wang, E.R. Kandel, and J. O'Dell. 1995. CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP. Cell 81: 891.
15. Meyer, T., P.I. Hanson, L. Stryer, and H. Schulman, 1992. Calmodulin trapping by calcium-calmodulin-dependent protein kinase. Science 256: 1199.
16. 2+-triggered molecular switch. Cell 44: 861.
17. 2+/calmodulin-dependent protein kinase in cultures of postnatal rat hippocampal slices. Proc. Natl. Acad. Sci. 88: 4756.
18. Müller, D., M. Oliver, and O. Lynch. 1989. Developmental changes in synaptic properties in hippocampus of neonatal rats. Dev. Brain Res. 49: 105.
19. O'Dell, T.J. and E.R. Kandel. 1994. Low-frequency stimulation erases LTP through an NMDA receptor-mediated activation of protein phosphatases. Learn. Mem. 1: 129.
20. Silva, A.J., R. Paylor, J.M. Wehner, and S. Tonegawa. 1992a. Deficient hippocampal long-term potentiation in α-calcium-calmodulin kinase II mutant mice. Science 257: 206.
21. Silva, A.J., C.F. Stevens, S. Tonegawa, and Y. Wang. 1992b. Impaired spatial learning in α-calcium-calmodulin kinase II mutant mice. Science 257: 201.
22. Tan, S.-E., R.J. Wenthold, and T.R. Soderling. 1994. Phosphorylation of AMPA-type glutamate receptors by calcium/calmodulin-dependent protein kinase II and protein kinase C in cultured hippocampal neurons. J. Neurosci. 14: 1123.
23. 2+-independent activity. Proc. Natl. Acad. Sci. 85: 6337.
24. 2+/independent for functional studies. Biochemistry 29: 1679.