메뉴 건너뛰기




Volumn 66, Issue 2, 2017, Pages 233-245

Immunosenescence: limitations of natural killer cell-based cancer immunotherapy

Author keywords

Ageing; Cancer immunotherapy; Checkpoint blockade; NK cell immunosenescence; PIVAC 15

Indexed keywords

LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MICRORNA; NATURAL KILLER CELL RECEPTOR;

EID: 84982112296     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-016-1882-x     Document Type: Review
Times cited : (35)

References (90)
  • 1
    • 84966832820 scopus 로고    scopus 로고
    • Lag-3, Tim-3, and TIGIT: co-inhibitory receptors with specialized functions in immune regulation
    • COI: 1:CAS:528:DC%2BC28XotFarsL4%3D, PID: 27192565
    • Anderson AC, Joller N, Kuchroo VK (2016) Lag-3, Tim-3, and TIGIT: co-inhibitory receptors with specialized functions in immune regulation. Immunity 44:989–1004. doi:10.1016/j.immuni.2016.05.001
    • (2016) Immunity , vol.44 , pp. 989-1004
    • Anderson, A.C.1    Joller, N.2    Kuchroo, V.K.3
  • 3
    • 84876466920 scopus 로고    scopus 로고
    • Prognostic significance of CD155 mRNA expression in soft tissue sarcomas
    • COI: 1:CAS:528:DC%2BC3sXpvVaqtL0%3D, PID: 23833639
    • Atsumi S, Matsumine A, Toyoda H, Niimi R, Iino T, Sudo A (2013) Prognostic significance of CD155 mRNA expression in soft tissue sarcomas. Oncol Lett 5:1771–1776. doi:10.3892/ol.2013.1280
    • (2013) Oncol Lett , vol.5 , pp. 1771-1776
    • Atsumi, S.1    Matsumine, A.2    Toyoda, H.3    Niimi, R.4    Iino, T.5    Sudo, A.6
  • 4
    • 23144462546 scopus 로고    scopus 로고
    • Cancer and ageing: a nexus at several levels
    • COI: 1:CAS:528:DC%2BD2MXmvVClt78%3D, PID: 16056261
    • Balducci L, Ershler WB (2005) Cancer and ageing: a nexus at several levels. Nat Rev Cancer 5:655–662. doi:10.1038/nrc1675
    • (2005) Nat Rev Cancer , vol.5 , pp. 655-662
    • Balducci, L.1    Ershler, W.B.2
  • 9
    • 84902582355 scopus 로고    scopus 로고
    • Retargeting NK-92 cells by means of CD19- and CD20-specific chimeric antigen receptors compares favorably with antibody-dependent cellular cytotoxicity
    • PID: 24404423
    • Boissel L, Betancur-Boissel M, Lu W, Krause DS, Van Etten RA, Wels WS, Klingemann H (2013) Retargeting NK-92 cells by means of CD19- and CD20-specific chimeric antigen receptors compares favorably with antibody-dependent cellular cytotoxicity. Oncoimmunology 2:e26527. doi:10.4161/onci.26527
    • (2013) Oncoimmunology , vol.2
    • Boissel, L.1    Betancur-Boissel, M.2    Lu, W.3    Krause, D.S.4    Van Etten, R.A.5    Wels, W.S.6    Klingemann, H.7
  • 10
    • 45449115527 scopus 로고    scopus 로고
    • Line of attack: NK cell specificity and integration of signals
    • COI: 1:CAS:528:DC%2BD1cXns1aht7k%3D, PID: 18439809
    • Bryceson YT, Long EO (2008) Line of attack: NK cell specificity and integration of signals. Curr Opin Immunol 20:344–352. doi:10.1016/j.coi.2008.03.005
    • (2008) Curr Opin Immunol , vol.20 , pp. 344-352
    • Bryceson, Y.T.1    Long, E.O.2
  • 11
    • 84940602849 scopus 로고    scopus 로고
    • Expression of NKp30, NKp46 and DNAM-1 activating receptors on resting and IL-2 activated NK cells from healthy donors according to CMV-serostatus and age
    • COI: 1:CAS:528:DC%2BC2MXovV2msL8%3D, PID: 25991472
    • Campos C, Lopez N, Pera A, Gordillo JJ, Hassouneh F, Tarazona R, Solana R (2015) Expression of NKp30, NKp46 and DNAM-1 activating receptors on resting and IL-2 activated NK cells from healthy donors according to CMV-serostatus and age. Biogerontology 16:671–683. doi:10.1007/s10522-015-9581-0
    • (2015) Biogerontology , vol.16 , pp. 671-683
    • Campos, C.1    Lopez, N.2    Pera, A.3    Gordillo, J.J.4    Hassouneh, F.5    Tarazona, R.6    Solana, R.7
  • 12
    • 84914158785 scopus 로고    scopus 로고
    • Proinflammatory status influences NK cells subsets in the elderly
    • COI: 1:CAS:528:DC%2BC2cXhtFOgt7nE, PID: 24998470
    • Campos C, Pera A, Lopez-Fernandez I, Alonso C, Tarazona R, Solana R (2014) Proinflammatory status influences NK cells subsets in the elderly. Immunol Lett 162:298–302. doi:10.1016/j.imlet.2014.06.015
    • (2014) Immunol Lett , vol.162 , pp. 298-302
    • Campos, C.1    Pera, A.2    Lopez-Fernandez, I.3    Alonso, C.4    Tarazona, R.5    Solana, R.6
  • 15
    • 67649657747 scopus 로고    scopus 로고
    • Expression of adhesion molecules and ligands for activating and costimulatory receptors involved in cell-mediated cytotoxicity in a large panel of human melanoma cell lines
    • COI: 1:CAS:528:DC%2BD1MXnslentrk%3D, PID: 19259667
    • Casado JG, Pawelec G, Morgado S, Sanchez-Correa B, Delgado E, Gayoso I, Duran E, Solana R, Tarazona R (2009) Expression of adhesion molecules and ligands for activating and costimulatory receptors involved in cell-mediated cytotoxicity in a large panel of human melanoma cell lines. Cancer Immunol Immunother 58:1517–1526. doi:10.1007/s00262-009-0682-y
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 1517-1526
    • Casado, J.G.1    Pawelec, G.2    Morgado, S.3    Sanchez-Correa, B.4    Delgado, E.5    Gayoso, I.6    Duran, E.7    Solana, R.8    Tarazona, R.9
  • 21
    • 84862816152 scopus 로고    scopus 로고
    • Natural killer cell differentiation from hematopoietic stem cells: a comparative analysis of heparin- and stromal cell-supported methods
    • COI: 1:CAS:528:DC%2BC38Xjs1ymtrg%3D, PID: 22155502
    • Dezell SA, Ahn YO, Spanholtz J, Wang H, Weeres M, Jackson S, Cooley S, Dolstra H, Miller JS, Verneris MR (2012) Natural killer cell differentiation from hematopoietic stem cells: a comparative analysis of heparin- and stromal cell-supported methods. Biol Blood Marrow Transplant 18:536–545. doi:10.1016/j.bbmt.2011.11.023
    • (2012) Biol Blood Marrow Transplant , vol.18 , pp. 536-545
    • Dezell, S.A.1    Ahn, Y.O.2    Spanholtz, J.3    Wang, H.4    Weeres, M.5    Jackson, S.6    Cooley, S.7    Dolstra, H.8    Miller, J.S.9    Verneris, M.R.10
  • 23
    • 17844363756 scopus 로고    scopus 로고
    • The influence of advanced age on cancer occurrence and growth
    • Balducci L, Extermann M, (eds), Springer, New York
    • Ershler WB (2005) The influence of advanced age on cancer occurrence and growth. In: Balducci L, Extermann M (eds) Biological basis of geriatric oncology. Springer, New York, pp 75–87
    • (2005) Biological basis of geriatric oncology , pp. 75-87
    • Ershler, W.B.1
  • 24
    • 33845987986 scopus 로고    scopus 로고
    • Deficient expression of NCR in NK cells from acute myeloid leukemia: evolution during leukemia treatment and impact of leukemia cells in NCRdull phenotype induction
    • COI: 1:CAS:528:DC%2BD2sXivVyru7o%3D, PID: 16940427
    • Fauriat C, Just-Landi S, Mallet F, Arnoulet C, Sainty D, Olive D, Costello RT (2007) Deficient expression of NCR in NK cells from acute myeloid leukemia: evolution during leukemia treatment and impact of leukemia cells in NCRdull phenotype induction. Blood 109:323–330. doi:10.1182/blood-2005-08-027979
    • (2007) Blood , vol.109 , pp. 323-330
    • Fauriat, C.1    Just-Landi, S.2    Mallet, F.3    Arnoulet, C.4    Sainty, D.5    Olive, D.6    Costello, R.T.7
  • 25
    • 84924501653 scopus 로고    scopus 로고
    • Cytomegalovirus (CMV) seropositivity decreases B cell responses to the influenza vaccine
    • COI: 1:CAS:528:DC%2BC2MXis1anu74%3D, PID: 25659271
    • Frasca D, Diaz A, Romero M, Landin AM, Blomberg BB (2015) Cytomegalovirus (CMV) seropositivity decreases B cell responses to the influenza vaccine. Vaccine 33:1433–1439. doi:10.1016/j.vaccine.2015.01.071
    • (2015) Vaccine , vol.33 , pp. 1433-1439
    • Frasca, D.1    Diaz, A.2    Romero, M.3    Landin, A.M.4    Blomberg, B.B.5
  • 26
    • 84925826065 scopus 로고    scopus 로고
    • Immunology of aging and cancer development
    • PID: 23503514
    • Fulop T, Larbi A, Kotb R, Pawelec G (2013) Immunology of aging and cancer development. Interdiscip Top Gerontol 38:38–48. doi:10.1159/000343599
    • (2013) Interdiscip Top Gerontol , vol.38 , pp. 38-48
    • Fulop, T.1    Larbi, A.2    Kotb, R.3    Pawelec, G.4
  • 31
    • 84878634049 scopus 로고    scopus 로고
    • Modulation of cancer traits by tumor suppressor microRNAs
    • COI: 1:CAS:528:DC%2BC3sXhs1ykt7Y%3D, PID: 23325049
    • Grammatikakis I, Gorospe M, Abdelmohsen K (2013) Modulation of cancer traits by tumor suppressor microRNAs. Int J Mol Sci 14:1822–1842. doi:10.3390/ijms14011822
    • (2013) Int J Mol Sci , vol.14 , pp. 1822-1842
    • Grammatikakis, I.1    Gorospe, M.2    Abdelmohsen, K.3
  • 32
    • 84933524356 scopus 로고    scopus 로고
    • Fully automated expansion and activation of clinical-grade natural killer cells for adoptive immunotherapy
    • COI: 1:CAS:528:DC%2BC2MXlsV2ntb0%3D, PID: 25881519
    • Granzin M, Soltenborn S, Muller S, Kollet J, Berg M, Cerwenka A, Childs RW, Huppert V (2015) Fully automated expansion and activation of clinical-grade natural killer cells for adoptive immunotherapy. Cytotherapy 17:621–632. doi:10.1016/j.jcyt.2015.03.611
    • (2015) Cytotherapy , vol.17 , pp. 621-632
    • Granzin, M.1    Soltenborn, S.2    Muller, S.3    Kollet, J.4    Berg, M.5    Cerwenka, A.6    Childs, R.W.7    Huppert, V.8
  • 33
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • COI: 1:CAS:528:DC%2BC3MXjsFeqtrk%3D, PID: 21376230
    • Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144:646–674. doi:10.1016/j.cell.2011.02.013
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 34
    • 0032532284 scopus 로고    scopus 로고
    • CD3/TCR complex-associated lymphocyte activation gene-3 molecules inhibit CD3/TCR signaling
    • COI: 1:CAS:528:DyaK1cXmsFyrtLc%3D, PID: 9780176
    • Hannier S, Tournier M, Bismuth G, Triebel F (1998) CD3/TCR complex-associated lymphocyte activation gene-3 molecules inhibit CD3/TCR signaling. J Immunol 161:4058–4065
    • (1998) J Immunol , vol.161 , pp. 4058-4065
    • Hannier, S.1    Tournier, M.2    Bismuth, G.3    Triebel, F.4
  • 35
    • 0016711166 scopus 로고
    • Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic acid allogeneic tumors. I. Distribution of reactivity and specificity
    • COI: 1:STN:280:DyaE2M3htVGqtg%3D%3D, PID: 50294
    • Herberman RB, Nunn ME, Lavrin DH (1975) Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic acid allogeneic tumors. I. Distribution of reactivity and specificity. Int J Cancer 16:216–229. doi:10.1002/ijc.2910160204
    • (1975) Int J Cancer , vol.16 , pp. 216-229
    • Herberman, R.B.1    Nunn, M.E.2    Lavrin, D.H.3
  • 36
    • 30744432128 scopus 로고    scopus 로고
    • Role of antibody-dependent cell-mediated cytotoxicity in the efficacy of therapeutic anti-cancer monoclonal antibodies
    • COI: 1:CAS:528:DC%2BD28XjsFGqtQ%3D%3D, PID: 16408158
    • Iannello A, Ahmad A (2005) Role of antibody-dependent cell-mediated cytotoxicity in the efficacy of therapeutic anti-cancer monoclonal antibodies. Cancer Metastasis Rev 24:487–499. doi:10.1007/s10555-005-6192-2
    • (2005) Cancer Metastasis Rev , vol.24 , pp. 487-499
    • Iannello, A.1    Ahmad, A.2
  • 37
    • 22044456688 scopus 로고    scopus 로고
    • Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells
    • COI: 1:CAS:528:DC%2BD2MXlvVWjt7k%3D, PID: 15755898
    • Imai C, Iwamoto S, Campana D (2005) Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells. Blood 106:376–383. doi:10.1182/blood-2004-12-4797
    • (2005) Blood , vol.106 , pp. 376-383
    • Imai, C.1    Iwamoto, S.2    Campana, D.3
  • 38
    • 84858126071 scopus 로고    scopus 로고
    • MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review
    • COI: 1:CAS:528:DC%2BC38XjsVSqs70%3D, PID: 22351564
    • Iorio MV, Croce CM (2012) MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review. EMBO Mol Med 4:143–159. doi:10.1002/emmm.201100209
    • (2012) EMBO Mol Med , vol.4 , pp. 143-159
    • Iorio, M.V.1    Croce, C.M.2
  • 41
    • 0016762220 scopus 로고
    • Natural” killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype
    • COI: 1:STN:280:DyaE2s%2FisF2htw%3D%3D, PID: 1234049
    • Kiessling R, Klein E, Wigzell H (1975) “Natural” killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype. Eur J Immunol 5:112–117. doi:10.1002/eji.1830050208
    • (1975) Eur J Immunol , vol.5 , pp. 112-117
    • Kiessling, R.1    Klein, E.2    Wigzell, H.3
  • 42
    • 84903733656 scopus 로고    scopus 로고
    • MicroRNA-150 regulates the cytotoxicity of natural killers by targeting perforin-1
    • COI: 1:CAS:528:DC%2BC2cXltl2ls78%3D, PID: 24698324
    • Kim N, Kim M, Yun S, Doh J, Greenberg PD, Kim TD, Choi I (2014) MicroRNA-150 regulates the cytotoxicity of natural killers by targeting perforin-1. J Allergy Clin Immunol 134:195–203. doi:10.1016/j.jaci.2014.02.018
    • (2014) J Allergy Clin Immunol , vol.134 , pp. 195-203
    • Kim, N.1    Kim, M.2    Yun, S.3    Doh, J.4    Greenberg, P.D.5    Kim, T.D.6    Choi, I.7
  • 46
    • 84897965082 scopus 로고    scopus 로고
    • The CD94/NKG2C+ NK-cell subset on the edge of innate and adaptive immunity to human cytomegalovirus infection
    • COI: 1:CAS:528:DC%2BC2cXkslelsro%3D, PID: 24666761
    • Lopez-Botet M, Muntasell A, Vilches C (2014) The CD94/NKG2C+ NK-cell subset on the edge of innate and adaptive immunity to human cytomegalovirus infection. Semin Immunol 26:145–151. doi:10.1016/j.smim.2014.03.002
    • (2014) Semin Immunol , vol.26 , pp. 145-151
    • Lopez-Botet, M.1    Muntasell, A.2    Vilches, C.3
  • 48
    • 79955011677 scopus 로고    scopus 로고
    • Human NK cells proliferate and die in vivo more rapidly than T cells in healthy young and elderly adults
    • COI: 1:CAS:528:DC%2BC3MXkt1GqsLw%3D, PID: 21402893
    • Lutz CT, Karapetyan A, Al-Attar A, Shelton BJ, Holt KJ, Tucker JH, Presnell SR (2011) Human NK cells proliferate and die in vivo more rapidly than T cells in healthy young and elderly adults. J Immunol 186:4590–4598. doi:10.4049/jimmunol.1002732
    • (2011) J Immunol , vol.186 , pp. 4590-4598
    • Lutz, C.T.1    Karapetyan, A.2    Al-Attar, A.3    Shelton, B.J.4    Holt, K.J.5    Tucker, J.H.6    Presnell, S.R.7
  • 49
    • 18844392519 scopus 로고    scopus 로고
    • Reciprocal age related change in natural killer cell receptors for MHC class I
    • COI: 1:CAS:528:DC%2BD2MXktVKqsb0%3D, PID: 15888327
    • Lutz CT, Moore MB, Bradley S, Shelton BJ, Lutgendorf SK (2005) Reciprocal age related change in natural killer cell receptors for MHC class I. Mech Ageing Dev 126:722–731. doi:10.1016/j.mad.2005.01.004
    • (2005) Mech Ageing Dev , vol.126 , pp. 722-731
    • Lutz, C.T.1    Moore, M.B.2    Bradley, S.3    Shelton, B.J.4    Lutgendorf, S.K.5
  • 50
    • 84938350452 scopus 로고    scopus 로고
    • Combination cancer immunotherapy and new immunomodulatory targets
    • COI: 1:CAS:528:DC%2BC2MXht1KiurrJ, PID: 26228759
    • Mahoney KM, Rennert PD, Freeman GJ (2015) Combination cancer immunotherapy and new immunomodulatory targets. Nat Rev Drug Discov 14:561–584. doi:10.1038/nrd4591
    • (2015) Nat Rev Drug Discov , vol.14 , pp. 561-584
    • Mahoney, K.M.1    Rennert, P.D.2    Freeman, G.J.3
  • 52
    • 84925743331 scopus 로고    scopus 로고
    • Balancing natural killer cell activation through paired receptors
    • COI: 1:CAS:528:DC%2BC2MXjvFOhtbw%3D, PID: 25743219
    • Martinet L, Smyth MJ (2015) Balancing natural killer cell activation through paired receptors. Nat Rev Immunol 15:243–254. doi:10.1038/nri3799
    • (2015) Nat Rev Immunol , vol.15 , pp. 243-254
    • Martinet, L.1    Smyth, M.J.2
  • 53
    • 58249118272 scopus 로고    scopus 로고
    • The story of human cytomegalovirus and cancer: increasing evidence and open questions
    • COI: 1:CAS:528:DC%2BD1MXhvVOls7w%3D, PID: 19107226
    • Michaelis M, Doerr HW, Cinatl J (2009) The story of human cytomegalovirus and cancer: increasing evidence and open questions. Neoplasia 11:1–9. doi:10.1593/neo.81178
    • (2009) Neoplasia , vol.11 , pp. 1-9
    • Michaelis, M.1    Doerr, H.W.2    Cinatl, J.3
  • 55
    • 77951149575 scopus 로고    scopus 로고
    • NCI first international workshop on the biology, prevention, and treatment of relapse after allogeneic hematopoietic stem cell transplantation: report from the committee on the biology underlying recurrence of malignant disease following allogeneic HSCT: graft-versus-tumor/leukemia reaction
    • PID: 20152921
    • Miller JS, Warren EH, van den Brink MR, Ritz J, Shlomchik WD, Murphy WJ, Barrett AJ, Kolb HJ, Giralt S, Bishop MR, Blazar BR, Falkenburg JH (2010) NCI first international workshop on the biology, prevention, and treatment of relapse after allogeneic hematopoietic stem cell transplantation: report from the committee on the biology underlying recurrence of malignant disease following allogeneic HSCT: graft-versus-tumor/leukemia reaction. Biol Blood Marrow Transplant 16:565–586. doi:10.1016/j.bbmt.2010.02.005
    • (2010) Biol Blood Marrow Transplant , vol.16 , pp. 565-586
    • Miller, J.S.1    Warren, E.H.2    van den Brink, M.R.3    Ritz, J.4    Shlomchik, W.D.5    Murphy, W.J.6    Barrett, A.J.7    Kolb, H.J.8    Giralt, S.9    Bishop, M.R.10    Blazar, B.R.11    Falkenburg, J.H.12
  • 56
    • 79959658972 scopus 로고    scopus 로고
    • NK cell recognition and killing of melanoma cells is controlled by multiple activating receptor-ligand interactions
    • COI: 1:CAS:528:DC%2BC3MXnvF2jtrw%3D, PID: 21576932
    • Morgado S, Sanchez-Correa B, Casado JG, Duran E, Gayoso I, Labella F, Solana R, Tarazona R (2011) NK cell recognition and killing of melanoma cells is controlled by multiple activating receptor-ligand interactions. J Innate Immun 3:365–373. doi:10.1159/000328505
    • (2011) J Innate Immun , vol.3 , pp. 365-373
    • Morgado, S.1    Sanchez-Correa, B.2    Casado, J.G.3    Duran, E.4    Gayoso, I.5    Labella, F.6    Solana, R.7    Tarazona, R.8
  • 57
    • 84939978516 scopus 로고    scopus 로고
    • Natural killer cell functional activity after 4-1BB costimulation
    • COI: 1:CAS:528:DC%2BC2cXitFyhur%2FI, PID: 25520217
    • Navabi S, Doroudchi M, Tashnizi AH, Habibagahi M (2015) Natural killer cell functional activity after 4-1BB costimulation. Inflammation 38:1181–1190. doi:10.1007/s10753-014-0082-0
    • (2015) Inflammation , vol.38 , pp. 1181-1190
    • Navabi, S.1    Doroudchi, M.2    Tashnizi, A.H.3    Habibagahi, M.4
  • 60
    • 84873406620 scopus 로고    scopus 로고
    • Elderly patients with colon cancer have unique tumor characteristics and poor survival
    • PID: 23011893
    • Patel SS, Nelson R, Sanchez J, Lee W, Uyeno L, Garcia-Aguilar J, Hurria A, Kim J (2013) Elderly patients with colon cancer have unique tumor characteristics and poor survival. Cancer 119:739–747. doi:10.1002/cncr.27753
    • (2013) Cancer , vol.119 , pp. 739-747
    • Patel, S.S.1    Nelson, R.2    Sanchez, J.3    Lee, W.4    Uyeno, L.5    Garcia-Aguilar, J.6    Hurria, A.7    Kim, J.8
  • 61
    • 84865302673 scopus 로고    scopus 로고
    • The impact of CMV infection on survival in older humans
    • COI: 1:CAS:528:DC%2BC38XmtlWhsrk%3D, PID: 22541724
    • Pawelec G, McElhaney JE, Aiello AE, Derhovanessian E (2012) The impact of CMV infection on survival in older humans. Curr Opin Immunol 24:507–511. doi:10.1016/j.coi.2012.04.002
    • (2012) Curr Opin Immunol , vol.24 , pp. 507-511
    • Pawelec, G.1    McElhaney, J.E.2    Aiello, A.E.3    Derhovanessian, E.4
  • 62
    • 84895736383 scopus 로고    scopus 로고
    • CMV latent infection improves CD8+ T response to SEB due to expansion of polyfunctional CD57+ cells in young individuals
    • PID: 24533103
    • Pera A, Campos C, Corona A, Sanchez-Correa B, Tarazona R, Larbi A, Solana R (2014) CMV latent infection improves CD8+ T response to SEB due to expansion of polyfunctional CD57+ cells in young individuals. PLoS ONE 9:e88538. doi:10.1371/journal.pone.0088538
    • (2014) PLoS ONE , vol.9
    • Pera, A.1    Campos, C.2    Corona, A.3    Sanchez-Correa, B.4    Tarazona, R.5    Larbi, A.6    Solana, R.7
  • 63
    • 84897041811 scopus 로고    scopus 로고
    • Orchestrating immune check-point blockade for cancer immunotherapy in combinations
    • COI: 1:CAS:528:DC%2BC2cXhsVyhu7Y%3D, PID: 24485523
    • Perez-Gracia JL, Labiano S, Rodriguez-Ruiz ME, Sanmamed MF, Melero I (2014) Orchestrating immune check-point blockade for cancer immunotherapy in combinations. Curr Opin Immunol 27:89–97. doi:10.1016/j.coi.2014.01.002
    • (2014) Curr Opin Immunol , vol.27 , pp. 89-97
    • Perez-Gracia, J.L.1    Labiano, S.2    Rodriguez-Ruiz, M.E.3    Sanmamed, M.F.4    Melero, I.5
  • 64
    • 84864421972 scopus 로고    scopus 로고
    • Tumor-induced changes in the phenotype of blood-derived and tumor-associated T cells of early stage breast cancer patients
    • COI: 1:CAS:528:DC%2BC38XhsVCit7Y%3D, PID: 22190148
    • Poschke I, De BJ, Mao Y, Kiessling R (2012) Tumor-induced changes in the phenotype of blood-derived and tumor-associated T cells of early stage breast cancer patients. Int J Cancer 131:1611–1620. doi:10.1002/ijc.27410
    • (2012) Int J Cancer , vol.131 , pp. 1611-1620
    • Poschke, I.1    De, B.J.2    Mao, Y.3    Kiessling, R.4
  • 65
    • 84875509728 scopus 로고    scopus 로고
    • Regulation of ligands for the NKG2D activating receptor
    • COI: 1:CAS:528:DC%2BC3sXnsFClsbw%3D, PID: 23298206
    • Raulet DH, Gasser S, Gowen BG, Deng W, Jung H (2013) Regulation of ligands for the NKG2D activating receptor. Annu Rev Immunol 31:413–441. doi:10.1146/annurev-immunol-032712-095951
    • (2013) Annu Rev Immunol , vol.31 , pp. 413-441
    • Raulet, D.H.1    Gasser, S.2    Gowen, B.G.3    Deng, W.4    Jung, H.5
  • 68
    • 84879703012 scopus 로고    scopus 로고
    • NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17)
    • COI: 1:CAS:528:DC%2BC3sXot1Khsrc%3D, PID: 23487023
    • Romee R, Foley B, Lenvik T, Wang Y, Zhang B, Ankarlo D, Luo X, Cooley S, Verneris M, Walcheck B, Miller J (2013) NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17). Blood 121:3599–3608. doi:10.1182/blood-2012-04-425397
    • (2013) Blood , vol.121 , pp. 3599-3608
    • Romee, R.1    Foley, B.2    Lenvik, T.3    Wang, Y.4    Zhang, B.5    Ankarlo, D.6    Luo, X.7    Cooley, S.8    Verneris, M.9    Walcheck, B.10    Miller, J.11
  • 69
    • 84920828341 scopus 로고    scopus 로고
    • Utilizing cytokines to function-enable human NK cells for the immunotherapy of cancer
    • PID: 25054077
    • Romee R, Leong JW, Fehniger TA (2014) Utilizing cytokines to function-enable human NK cells for the immunotherapy of cancer. Scientifica 2014:205796. doi:10.1155/2014/205796
    • (2014) Scientifica , vol.2014 , pp. 205796
    • Romee, R.1    Leong, J.W.2    Fehniger, T.A.3
  • 73
    • 84855445932 scopus 로고    scopus 로고
    • Decreased expression of DNAM-1 on NK cells from acute myeloid leukemia patients
    • COI: 1:CAS:528:DC%2BC38Xkslyktg%3D%3D, PID: 21383766
    • Sanchez-Correa B, Gayoso I, Bergua JM, Casado JG, Morgado S, Solana R, Tarazona R (2012) Decreased expression of DNAM-1 on NK cells from acute myeloid leukemia patients. Immunol Cell Biol 90:109–115. doi:10.1038/icb.2011.15
    • (2012) Immunol Cell Biol , vol.90 , pp. 109-115
    • Sanchez-Correa, B.1    Gayoso, I.2    Bergua, J.M.3    Casado, J.G.4    Morgado, S.5    Solana, R.6    Tarazona, R.7
  • 77
    • 84899686409 scopus 로고    scopus 로고
    • Shaping of NK cell subsets by aging
    • COI: 1:CAS:528:DC%2BC2cXht1Kht7jF, PID: 24792889
    • Solana R, Campos C, Pera A, Tarazona R (2014) Shaping of NK cell subsets by aging. Curr Opin Immunol 29:56–61. doi:10.1016/j.coi.2014.04.002
    • (2014) Curr Opin Immunol , vol.29 , pp. 56-61
    • Solana, R.1    Campos, C.2    Pera, A.3    Tarazona, R.4
  • 78
    • 0033951533 scopus 로고    scopus 로고
    • NK and NK/T cells in human senescence
    • COI: 1:CAS:528:DC%2BD3cXisVKmsbc%3D, PID: 10689137
    • Solana R, Mariani E (2000) NK and NK/T cells in human senescence. Vaccine 18:1613–1620. doi:10.1016/S0264-410X(99)00495-8
    • (2000) Vaccine , vol.18 , pp. 1613-1620
    • Solana, R.1    Mariani, E.2
  • 79
    • 84946780179 scopus 로고    scopus 로고
    • NK-92: an ‘off-the-shelf therapeutic’ for adoptive natural killer cell-based cancer immunotherapy
    • COI: 1:CAS:528:DC%2BC2MXhvVeqsb7L, PID: 26559813
    • Suck G, Odendahl M, Nowakowska P, Seidl C, Wels WS, Klingemann HG, Tonn T (2016) NK-92: an ‘off-the-shelf therapeutic’ for adoptive natural killer cell-based cancer immunotherapy. Cancer Immunol Immunother 65:485–492. doi:10.1007/s00262-015-1761-x
    • (2016) Cancer Immunol Immunother , vol.65 , pp. 485-492
    • Suck, G.1    Odendahl, M.2    Nowakowska, P.3    Seidl, C.4    Wels, W.S.5    Klingemann, H.G.6    Tonn, T.7
  • 80
    • 84883658922 scopus 로고    scopus 로고
    • MicroRNA regulation of natural killer cells
    • PID: 23450173
    • Sullivan RP, Leong JW, Fehniger TA (2013) MicroRNA regulation of natural killer cells. Front Immunol 4:44. doi:10.3389/fimmu.2013.00044
    • (2013) Front Immunol , vol.4 , pp. 44
    • Sullivan, R.P.1    Leong, J.W.2    Fehniger, T.A.3
  • 81
    • 16544371710 scopus 로고    scopus 로고
    • Enrollment of elderly patients in clinical trials for cancer drug registration: a 7-year experience by the US Food and Drug Administration
    • PID: 15542812
    • Talarico L, Chen G, Pazdur R (2004) Enrollment of elderly patients in clinical trials for cancer drug registration: a 7-year experience by the US Food and Drug Administration. J Clin Oncol 22:4626–4631. doi:10.1200/JCO.2004.02.175
    • (2004) J Clin Oncol , vol.22 , pp. 4626-4631
    • Talarico, L.1    Chen, G.2    Pazdur, R.3
  • 82
    • 84958153455 scopus 로고    scopus 로고
    • Natural killer cell recognition of melanoma: new clues for a more effective immunotherapy
    • PID: 26779186
    • Tarazona R, Duran E, Solana R (2016) Natural killer cell recognition of melanoma: new clues for a more effective immunotherapy. Front Immunol 6:649. doi:10.3389/fimmu.2015.00649
    • (2016) Front Immunol , vol.6 , pp. 649
    • Tarazona, R.1    Duran, E.2    Solana, R.3
  • 84
    • 53549114206 scopus 로고    scopus 로고
    • NK cells and cancer immunosurveillance
    • COI: 1:CAS:528:DC%2BD1cXhtF2msbnE, PID: 18836474
    • Waldhauer I, Steinle A (2008) NK cells and cancer immunosurveillance. Oncogene 27:5932–5943. doi:10.1038/onc.2008.267
    • (2008) Oncogene , vol.27 , pp. 5932-5943
    • Waldhauer, I.1    Steinle, A.2
  • 85
    • 84903945401 scopus 로고    scopus 로고
    • LSECtin expressed on melanoma cells promotes tumor progression by inhibiting antitumor T-cell responses
    • COI: 1:CAS:528:DC%2BC2cXhtVKlurjI, PID: 24769443
    • Xu F, Liu J, Liu D, Liu B, Wang M, Hu Z, Du X, Tang L, He F (2014) LSECtin expressed on melanoma cells promotes tumor progression by inhibiting antitumor T-cell responses. Cancer Res 74:3418–3428. doi:10.1158/0008-5472.CAN-13-2690
    • (2014) Cancer Res , vol.74 , pp. 3418-3428
    • Xu, F.1    Liu, J.2    Liu, D.3    Liu, B.4    Wang, M.5    Hu, Z.6    Du, X.7    Tang, L.8    He, F.9
  • 86
    • 84982910720 scopus 로고    scopus 로고
    • Clinical implications of human leukocyte antigen class I expression in endometrial cancer
    • PID: 26807234
    • Yakabe K, Murakami A, Nishimoto Y, Kajimura T, Sueoka K, Sugino N (2015) Clinical implications of human leukocyte antigen class I expression in endometrial cancer. Mol Clin Oncol 3:1285–1290. doi:10.3892/mco.2015.636
    • (2015) Mol Clin Oncol , vol.3 , pp. 1285-1290
    • Yakabe, K.1    Murakami, A.2    Nishimoto, Y.3    Kajimura, T.4    Sueoka, K.5    Sugino, N.6
  • 90
    • 84878784248 scopus 로고    scopus 로고
    • Matrix metalloproteinases inhibition promotes the polyfunctionality of human natural killer cells in therapeutic antibody-based anti-tumour immunotherapy
    • COI: 1:CAS:528:DC%2BC3sXptFehtbw%3D, PID: 23607800
    • Zhou Q, Gil-Krzewska A, Peruzzi G, Borrego F (2013) Matrix metalloproteinases inhibition promotes the polyfunctionality of human natural killer cells in therapeutic antibody-based anti-tumour immunotherapy. Clin Exp Immunol 173:131–139. doi:10.1111/cei.12095
    • (2013) Clin Exp Immunol , vol.173 , pp. 131-139
    • Zhou, Q.1    Gil-Krzewska, A.2    Peruzzi, G.3    Borrego, F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.