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Volumn 203, Issue 4, 2016, Pages 1807-1825

Refining the use of linkage disequilibrium as a robust signature of selective sweeps

Author keywords

Genetic map; Linkage disequilibrium; Positive selection; Recombination rate

Indexed keywords

ARTICLE; CONTROLLED STUDY; GENE LINKAGE DISEQUILIBRIUM; GENETIC RECOMBINATION; GENETIC VARIATION; HAPLOTYPE; HAPLOTYPE MAP; POPULATION DIFFERENTIATION; PRIORITY JOURNAL; SELECTIVE SWEEP; SIMULATION; STATISTICS; VARIANCE; GENETIC SELECTION; GENETICS; GENOMICS; HUMAN; POPULATION GENETICS; STATISTICS AND NUMERICAL DATA; THEORETICAL MODEL;

EID: 84981516310     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.115.185900     Document Type: Article
Times cited : (12)

References (78)
  • 1
    • 84879344554 scopus 로고    scopus 로고
    • Central precocious puberty caused by mutations in the imprinted gene MKRN3
    • Abreu, A. P., A. Dauber, D. B. Macedo, S. D. Noel, V. N. Brito et al., 2013 Central precocious puberty caused by mutations in the imprinted gene MKRN3. N. Engl. J. Med. 368: 2467–2475.
    • (2013) N. Engl. J. Med , vol.368 , pp. 2467-2475
    • Abreu, A.P.1    Dauber, A.2    Macedo, D.B.3    Noel, S.D.4    Brito, V.N.5
  • 2
    • 65149103048 scopus 로고    scopus 로고
    • Constructing genomic maps of positive selection in humans: Where do we go from here?
    • Akey, J. M., 2009 Constructing genomic maps of positive selection in humans: Where do we go from here? Genome Res. 19: 711–722.
    • (2009) Genome Res , vol.19 , pp. 711-722
    • Akey, J.M.1
  • 3
    • 84866654437 scopus 로고    scopus 로고
    • Exploiting multi-grain parallelism for efficient selective sweep detection
    • Springer-Verlag, Berlin/Heidelberg, Germany/New York
    • Alachiotis, N., P. Pavlidis, and A. Stamatakis, 2012a Exploiting multi-grain parallelism for efficient selective sweep detection, pp. 56–68 in Algorithms and Architectures for Parallel Processing. Springer-Verlag, Berlin/Heidelberg, Germany/New York.
    • (2012) Algorithms and Architectures for Parallel Processing , pp. 56-68
    • Alachiotis, N.1    Pavlidis, P.2    Stamatakis, A.3
  • 4
    • 84865553595 scopus 로고    scopus 로고
    • OmegaPlus: A scalable tool for rapid detection of selective sweeps in wholegenome datasets
    • Alachiotis, N., A. Stamatakis, and P. Pavlidis, 2012b OmegaPlus: a scalable tool for rapid detection of selective sweeps in wholegenome datasets. Bioinformatics 28: 2274–2275.
    • (2012) Bioinformatics , vol.28 , pp. 2274-2275
    • Alachiotis, N.1    Stamatakis, A.2    Pavlidis, P.3
  • 6
    • 68249118173 scopus 로고    scopus 로고
    • Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense
    • Barreiro, L. B., M. Ben-Ali, H. Quach, G. Laval, E. Patin et al., 2009 Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense. PLoS Genet. 5: e1000562.
    • (2009) Plos Genet , vol.5
    • Barreiro, L.B.1    Ben-Ali, M.2    Quach, H.3    Laval, G.4    Patin, E.5
  • 7
    • 80054759105 scopus 로고    scopus 로고
    • Molecular spandrels: Tests of adaptation at the genetic level
    • Barrett, R. D., and H. E. Hoekstra, 2011 Molecular spandrels: tests of adaptation at the genetic level. Nat. Rev. Genet. 12: 767–780.
    • (2011) Nat. Rev. Genet , vol.12 , pp. 767-780
    • Barrett, R.D.1    Hoekstra, H.E.2
  • 9
    • 27544482154 scopus 로고    scopus 로고
    • Genomic regions exhibiting positive selection identified from dense genotype data
    • Carlson, C. S., D. J. Thomas, M. A. Eberle, J. E. Swanson, R. J. Livingston et al., 2005 Genomic regions exhibiting positive selection identified from dense genotype data. Genome Res. 15: 1553–1565.
    • (2005) Genome Res , vol.15 , pp. 1553-1565
    • Carlson, C.S.1    Thomas, D.J.2    Eberle, M.A.3    Swanson, J.E.4    Livingston, R.J.5
  • 10
    • 84869204665 scopus 로고    scopus 로고
    • Population and sex differences in Drosophila melanogaster brain gene expression
    • Catalán, A., S. Hutter, and J. Parsch, 2012 Population and sex differences in Drosophila melanogaster brain gene expression. BMC Genomics 13: 654.
    • (2012) BMC Genomics , vol.13 , pp. 654
    • Catalán, A.1    Hutter, S.2    Parsch, J.3
  • 11
    • 77649260327 scopus 로고    scopus 로고
    • Population differentiation as a test for selective sweeps
    • Chen, H., N. Patterson, and D. Reich, 2010 Population differentiation as a test for selective sweeps. Genome Res. 20: 393–402.
    • (2010) Genome Res , vol.20 , pp. 393-402
    • Chen, H.1    Patterson, N.2    Reich, D.3
  • 12
    • 84920567005 scopus 로고    scopus 로고
    • A selective sweep on a deleterious mutation in CPT1A in arctic populations
    • Clemente, F. J., A. Cardona, C. E. Inchley, B. M. Peter, G. Jacobs et al., 2014 A selective sweep on a deleterious mutation in CPT1A in arctic populations. Am. J. Hum. Genet. 95: 584–589.
    • (2014) Am. J. Hum. Genet , vol.95 , pp. 584-589
    • Clemente, F.J.1    Cardona, A.2    Inchley, C.E.3    Peter, B.M.4    Jacobs, G.5
  • 13
    • 84912072340 scopus 로고    scopus 로고
    • Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences
    • Colonna, V., Q. Ayub, Y. Chen, L. Pagani, P. Luisi et al., 2014 Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences. Genome Biol. 15: R88.
    • (2014) Genome Biol , vol.15 , pp. 88
    • Colonna, V.1    Ayub, Q.2    Chen, Y.3    Pagani, L.4    Luisi, P.5
  • 14
    • 84890265468 scopus 로고    scopus 로고
    • The impact of equilibrium assumptions on tests of selection
    • Crisci, J. L., Y.-P. Poh, S. Mahajan, and J. D. Jensen, 2013 The impact of equilibrium assumptions on tests of selection. Front. Genet. 4: 235.
    • (2013) Front. Genet , vol.4 , pp. 235
    • Crisci, J.L.1    Poh, Y.-P.2    Mahajan, S.3    Jensen, J.D.4
  • 16
    • 84901393253 scopus 로고    scopus 로고
    • Genome-wide signals of positive selection in human evolution
    • Enard, D., P. W. Messer, and D. A. Petrov, 2014 Genome-wide signals of positive selection in human evolution. Genome Res. 24: 885–895.
    • (2014) Genome Res , vol.24 , pp. 885-895
    • Enard, D.1    Messer, P.W.2    Petrov, D.A.3
  • 17
    • 77955381733 scopus 로고    scopus 로고
    • MSMS: A coalescent simulation program including recombination, demographic structure and selection at a single locus
    • Ewing, G., and J. Hermisson, 2010 MSMS: a coalescent simulation program including recombination, demographic structure and selection at a single locus. Bioinformatics 26: 2064–2065.
    • (2010) Bioinformatics , vol.26 , pp. 2064-2065
    • Ewing, G.1    Hermisson, J.2
  • 18
    • 84927125338 scopus 로고    scopus 로고
    • PopPlanner: Visually constructing demographic models for simulation
    • Ewing, G. B., P. A. Reiff, and J. D. Jensen, 2015 PopPlanner: visually constructing demographic models for simulation. Front. Genet. 6: 150.
    • (2015) Front. Genet , vol.6 , pp. 150
    • Ewing, G.B.1    Reiff, P.A.2    Jensen, J.D.3
  • 19
    • 84899542092 scopus 로고    scopus 로고
    • On detecting incomplete soft or hard selective sweeps using haplotype structure
    • Ferrer-Admetlla, A., M. Liang, T. Korneliussen, and R. Nielsen, 2014 On detecting incomplete soft or hard selective sweeps using haplotype structure. Mol. Biol. Evol. 31: 1275–1291.
    • (2014) Mol. Biol. Evol , vol.31 , pp. 1275-1291
    • Ferrer-Admetlla, A.1    Liang, M.2    Korneliussen, T.3    Nielsen, R.4
  • 20
    • 84928704517 scopus 로고    scopus 로고
    • Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
    • Florio, M., M. Albert, E. Taverna, T. Namba, H. Brandl et al., 2015 Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion. Science 347: 1465–1470.
    • (2015) Science , vol.347 , pp. 1465-1470
    • Florio, M.1    Albert, M.2    Taverna, E.3    Namba, T.4    Brandl, H.5
  • 21
    • 35348983887 scopus 로고    scopus 로고
    • A second generation human haplotype map of over 3.1 million SNPs
    • Frazer, K. A., D. G. Ballinger, D. R. Cox, D. A. Hinds, L. L. Stuve et al., 2007 A second generation human haplotype map of over 3.1 million SNPs. Nature 449: 851–861.
    • (2007) Nature , vol.449 , pp. 851-861
    • Frazer, K.A.1    Ballinger, D.G.2    Cox, D.R.3    Hinds, D.A.4    Stuve, L.L.5
  • 22
    • 33646487014 scopus 로고    scopus 로고
    • Exact coalescent for the Wright–Fisher model
    • Fu, Y.-X., 2006 Exact coalescent for the Wright–Fisher model. Theor. Popul. Biol. 69: 385–394.
    • (2006) Theor. Popul. Biol , vol.69 , pp. 385-394
    • Fu, Y.-X.1
  • 23
    • 84924411185 scopus 로고    scopus 로고
    • Recent selective sweeps in North American Drosophila melanogaster show signatures of soft sweeps
    • Garud, N. R., P. W. Messer, E. O. Buzbas, and D. A. Petrov, 2015 Recent selective sweeps in North American Drosophila melanogaster show signatures of soft sweeps. PLoS Genet. 11: e1005004.
    • (2015) Plos Genet , vol.11
    • Garud, N.R.1    Messer, P.W.2    Buzbas, E.O.3    Petrov, D.A.4
  • 25
    • 73449149044 scopus 로고    scopus 로고
    • Inferring the joint demographic history of multiple populations from multidimensional SNP frequency data
    • Gutenkunst, R. N., R. D. Hernandez, S. H. Williamson, and C. D. Bustamante, 2009 Inferring the joint demographic history of multiple populations from multidimensional SNP frequency data. PLoS Genet. 5: e1000695.
    • (2009) Plos Genet , vol.5
    • Gutenkunst, R.N.1    Hernandez, R.D.2    Williamson, S.H.3    Bustamante, C.D.4
  • 26
    • 84879671007 scopus 로고    scopus 로고
    • Inferring demographic history from a spectrum of shared haplotype lengths
    • Harris, K., and R. Nielsen, 2013 Inferring demographic history from a spectrum of shared haplotype lengths. PLoS Genet. 9: e1003521.
    • (2013) Plos Genet , vol.9
    • Harris, K.1    Nielsen, R.2
  • 27
    • 18844439645 scopus 로고    scopus 로고
    • Soft sweeps: Molecular population genetics of adaptation from standing genetic variation
    • Hermisson, J., and P. S. Pennings, 2005 Soft sweeps: molecular population genetics of adaptation from standing genetic variation. Genetics 169: 2335–2352.
    • (2005) Genetics , vol.169 , pp. 2335-2352
    • Hermisson, J.1    Pennings, P.S.2
  • 28
    • 79951829399 scopus 로고    scopus 로고
    • Classic selective sweeps were rare in recent human evolution
    • Hernandez, R. D., J. L. Kelley, E. Elyashiv, S. C. Melton, A. Auton et al., 2011 Classic selective sweeps were rare in recent human evolution. Science 331: 920–924.
    • (2011) Science , vol.331 , pp. 920-924
    • Hernandez, R.D.1    Kelley, J.L.2    Elyashiv, E.3    Melton, S.C.4    Auton, A.5
  • 29
    • 33646226097 scopus 로고
    • Linkage disequilibrium in finite populations
    • Hill, W., and A. Robertson, 1968 Linkage disequilibrium in finite populations. Theor. Appl. Genet. 38: 226–231.
    • (1968) Theor. Appl. Genet , vol.38 , pp. 226-231
    • Hill, W.1    Robertson, A.2
  • 30
    • 80054760378 scopus 로고    scopus 로고
    • Variation in the mutation rate across mammalian genomes
    • Hodgkinson, A., and A. Eyre-Walker, 2011 Variation in the mutation rate across mammalian genomes. Nat. Rev. Genet. 12: 756– 766.
    • (2011) Nat. Rev. Genet , vol.12
    • Hodgkinson, A.1    Eyre-Walker, A.2
  • 31
    • 0023760376 scopus 로고
    • The coalescent process in models with selection and recombination
    • Hudson, R. R., and N. L. Kaplan, 1988 The coalescent process in models with selection and recombination. Genetics 120: 831–840.
    • (1988) Genetics , vol.120 , pp. 831-840
    • Hudson, R.R.1    Kaplan, N.L.2
  • 33
    • 34548395446 scopus 로고    scopus 로고
    • On the utility of linkage disequilibrium as a statistic for identifying targets of positive selection in nonequilibrium populations
    • Jensen, J. D., K. R. Thornton, C. D. Bustamante, and C. F. Aquadro, 2007 On the utility of linkage disequilibrium as a statistic for identifying targets of positive selection in nonequilibrium populations. Genetics 176: 2371–2379.
    • (2007) Genetics , vol.176 , pp. 2371-2379
    • Jensen, J.D.1    Thornton, K.R.2    Bustamante, C.D.3    Aquadro, C.F.4
  • 35
    • 33746693757 scopus 로고    scopus 로고
    • Genomic signatures of positive selection in humans and the limits of outlier approaches
    • Kelley, J. L., J. Madeoy, J. C. Calhoun, W. Swanson, and J. M. Akey, 2006 Genomic signatures of positive selection in humans and the limits of outlier approaches. Genome Res. 16: 980–989.
    • (2006) Genome Res , vol.16 , pp. 980-989
    • Kelley, J.L.1    Madeoy, J.2    Calhoun, J.C.3    Swanson, W.4    Akey, J.M.5
  • 36
    • 0030873114 scopus 로고    scopus 로고
    • A test of neutrality based on interlocus associations
    • Kelly, J. K., 1997 A test of neutrality based on interlocus associations. Genetics 146: 1197–1206.
    • (1997) Genetics , vol.146 , pp. 1197-1206
    • Kelly, J.K.1
  • 37
    • 3843073210 scopus 로고    scopus 로고
    • Linkage disequilibrium as a signature of selective sweeps
    • Kim, Y., and R. Nielsen, 2004 Linkage disequilibrium as a signature of selective sweeps. Genetics 167: 1513–1524.
    • (2004) Genetics , vol.167 , pp. 1513-1524
    • Kim, Y.1    Nielsen, R.2
  • 38
    • 60849114470 scopus 로고    scopus 로고
    • Simulation of DNA sequence evolution under models of recent directional selection
    • Kim, Y., and T. Wiehe, 2009 Simulation of DNA sequence evolution under models of recent directional selection. Brief. Bioinform. 10: 84–96.
    • (2009) Brief. Bioinform , vol.10 , pp. 84-96
    • Kim, Y.1    Wiehe, T.2
  • 39
    • 0002556819 scopus 로고
    • On the genealogy of large populations
    • Kingman, J. F., 1982 On the genealogy of large populations. J. Appl. Probab. 19: 27–43.
    • (1982) J. Appl. Probab , vol.19 , pp. 27-43
    • Kingman, J.F.1
  • 40
    • 78049354879 scopus 로고    scopus 로고
    • Fine-scale recombination rate differences between sexes, populations and individuals
    • Kong, A., G. Thorleifsson, D. F. Gudbjartsson, G. Masson, A. Sigurdsson et al., 2010 Fine-scale recombination rate differences between sexes, populations and individuals. Nature 467: 1099– 1103.
    • (2010) Nature , vol.467
    • Kong, A.1    Thorleifsson, G.2    Gudbjartsson, D.F.3    Masson, G.4    Sigurdsson, A.5
  • 41
    • 84881306743 scopus 로고    scopus 로고
    • Genetic variants and signatures of selective sweep of Hanwoo population (Korean native cattle)
    • Lee, T., S. Cho, K. S. Seo, J. Chang, H. Kim et al., 2013 Genetic variants and signatures of selective sweep of Hanwoo population (Korean native cattle). BMB Rep. 46: 346–351.
    • (2013) BMB Rep , vol.46 , pp. 346-351
    • Lee, T.1    Cho, S.2    Seo, K.S.3    Chang, J.4    Kim, H.5
  • 42
    • 66049087893 scopus 로고    scopus 로고
    • The difficulty of avoiding false positives in genome scans for natural selection
    • Mallick, S., S. Gnerre, P. Muller, and D. Reich, 2009 The difficulty of avoiding false positives in genome scans for natural selection. Genome Res. 19: 922–933.
    • (2009) Genome Res , vol.19 , pp. 922-933
    • Mallick, S.1    Gnerre, S.2    Muller, P.3    Reich, D.4
  • 43
  • 44
    • 0024370623 scopus 로고
    • Analyzing a portion of the ROC curve
    • McClish, D. K., 1989 Analyzing a portion of the ROC curve. Med. Decis. Making 9: 190–195.
    • (1989) Med. Decis. Making , vol.9 , pp. 190-195
    • McClish, D.K.1
  • 45
    • 34249005874 scopus 로고    scopus 로고
    • The structure of linkage disequilibrium around a selective sweep
    • McVean, G., 2007 The structure of linkage disequilibrium around a selective sweep. Genetics 175: 1395–1406.
    • (2007) Genetics , vol.175 , pp. 1395-1406
    • McVean, G.1
  • 46
    • 2142773942 scopus 로고    scopus 로고
    • The fine-scale structure of recombination rate variation in the human genome
    • McVean, G. A., S. R. Myers, S. Hunt, P. Deloukas, D. R. Bentley et al., 2004 The fine-scale structure of recombination rate variation in the human genome. Science 304: 581–584.
    • (2004) Science , vol.304 , pp. 581-584
    • McVean, G.A.1    Myers, S.R.2    Hunt, S.3    Deloukas, P.4    Bentley, D.R.5
  • 47
    • 84885911072 scopus 로고    scopus 로고
    • Population genomics of rapid adaptation by soft selective sweeps
    • Messer, P. W., and D. A. Petrov, 2013 Population genomics of rapid adaptation by soft selective sweeps. Trends Ecol. Evol. 28: 659–669.
    • (2013) Trends Ecol. Evol , vol.28 , pp. 659-669
    • Messer, P.W.1    Petrov, D.A.2
  • 48
    • 0018079655 scopus 로고
    • Basic principles of ROC analysis
    • Metz, C. E., 1978 Basic principles of ROC analysis. Semin. Nucl. Med. 8: 283–298.
    • (1978) Semin. Nucl. Med , vol.8 , pp. 283-298
    • Metz, C.E.1
  • 49
    • 33747171699 scopus 로고    scopus 로고
    • Meiotic recombination hotspots in plants
    • Mezard, C., 2006 Meiotic recombination hotspots in plants. Biochem. Soc. Trans. 34: 531–534.
    • (2006) Biochem. Soc. Trans , vol.34 , pp. 531-534
    • Mezard, C.1
  • 50
    • 77957959525 scopus 로고    scopus 로고
    • The neutral theory of molecular evolution in the genomic era
    • Nei, M., Y. Suzuki, and M. Nozawa, 2010 The neutral theory of molecular evolution in the genomic era. Annu. Rev. Genomics Hum. Genet. 11: 265–289.
    • (2010) Annu. Rev. Genomics Hum. Genet , vol.11 , pp. 265-289
    • Nei, M.1    Suzuki, Y.2    Nozawa, M.3
  • 52
    • 45849145445 scopus 로고    scopus 로고
    • Identifying selected regions from heterozygosity and divergence using a light-coverage genomic dataset from two human populations
    • Oleksyk, T. K., K. Zhao, M. Francisco, D. A. Gilbert, S. J. O’Brien et al., 2008 Identifying selected regions from heterozygosity and divergence using a light-coverage genomic dataset from two human populations. PLoS One 3: e1712.
    • (2008) Plos One , vol.3
    • Oleksyk, T.K.1    Zhao, K.2    Francisco, M.3    Gilbert, D.A.4    O’Brien, S.J.5
  • 53
    • 84975795680 scopus 로고    scopus 로고
    • An integrated map of genetic variation from 1,092 human genomes
    • Genomes Project Consortium, G. R. Abecasis, A. Auton, L. D. Brooks, M. A. DePristo et al., 2012 An integrated map of genetic variation from 1,092 human genomes. Nature 491: 56–65.
    • (2012) Nature , vol.491 , pp. 56-65
    • Abecasis, G.R.1    Auton, A.2    Brooks, L.D.3    Depristo, M.A.4
  • 54
    • 48949088705 scopus 로고    scopus 로고
    • Confounding between recombination and selection, and the ped/pop method for detecting selection
    • O’Reilly, P. F., E. Birney, and D. J. Balding, 2008 Confounding between recombination and selection, and the ped/pop method for detecting selection. Genome Res. 18: 1304–1313.
    • (2008) Genome Res , vol.18 , pp. 1304-1313
    • O’Reilly, P.F.1    Birney, E.2    Balding, D.J.3
  • 55
    • 84981502573 scopus 로고    scopus 로고
    • Genomic analyses inform on migration events during the peopling of Eurasia
    • Pagani, L., D. J. Lawson, E. Jagoda, A. Mörseburg, A. Eriksson et al., 2016 Genomic analyses inform on migration events during the peopling of Eurasia. Nature (in press).
    • (2016) Nature
    • Pagani, L.1    Lawson, D.J.2    Jagoda, E.3    Mörseburg, A.4    Eriksson, A.5
  • 56
    • 77249144000 scopus 로고    scopus 로고
    • Mammalian recombination hot spots: Properties, control and evolution
    • Paigen, K., and P. Petkov, 2010 Mammalian recombination hot spots: properties, control and evolution. Nat. Rev. Genet. 11: 221–233.
    • (2010) Nat. Rev. Genet , vol.11 , pp. 221-233
    • Paigen, K.1    Petkov, P.2
  • 57
    • 77955759338 scopus 로고    scopus 로고
    • Searching for footprints of positive selection in whole-genome SNP data from nonequilibrium populations
    • Pavlidis, P., J. D. Jensen, and W. Stephan, 2010 Searching for footprints of positive selection in whole-genome SNP data from nonequilibrium populations. Genetics 185: 907–922.
    • (2010) Genetics , vol.185 , pp. 907-922
    • Pavlidis, P.1    Jensen, J.D.2    Stephan, W.3
  • 58
    • 33845971545 scopus 로고    scopus 로고
    • Soft sweeps III: The signature of positive selection from recurrent mutation
    • Pennings, P. S., and J. Hermisson, 2006 Soft sweeps III: the signature of positive selection from recurrent mutation. PLoS Genet. 2: e186.
    • (2006) Plos Genet , vol.2
    • Pennings, P.S.1    Hermisson, J.2
  • 59
    • 84908024873 scopus 로고    scopus 로고
    • Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche
    • Perry, J. R., F. Day, C. E. Elks, P. Sulem, D. J. Thompson et al., 2014 Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature 514: 92–97.
    • (2014) Nature , vol.514 , pp. 92-97
    • Perry, J.R.1    Day, F.2    Elks, C.E.3    Sulem, P.4    Thompson, D.J.5
  • 60
    • 84868152411 scopus 로고    scopus 로고
    • Distinguishing between selective sweeps from standing variation and from a de novo mutation
    • Peter, B. M., E. Huerta-Sanchez, and R. Nielsen, 2012 Distinguishing between selective sweeps from standing variation and from a de novo mutation. PLoS Genet. 8: e1003011.
    • (2012) Plos Genet , vol.8
    • Peter, B.M.1    Huerta-Sanchez, E.2    Nielsen, R.3
  • 61
    • 0035345013 scopus 로고    scopus 로고
    • Meiotic recombination hot spots and cold spots
    • Petes, T. D., 2001 Meiotic recombination hot spots and cold spots. Nat. Rev. Genet. 2: 360–369.
    • (2001) Nat. Rev. Genet , vol.2 , pp. 360-369
    • Petes, T.D.1
  • 62
    • 52049100862 scopus 로고    scopus 로고
    • Linkage disequilibrium under genetic hitchhiking in finite populations
    • Pfaffelhuber, P., A. Lehnert, and W. Stephan, 2008 Linkage disequilibrium under genetic hitchhiking in finite populations. Genetics 179: 527–537.
    • (2008) Genetics , vol.179 , pp. 527-537
    • Pfaffelhuber, P.1    Lehnert, A.2    Stephan, W.3
  • 63
    • 54149088214 scopus 로고    scopus 로고
    • Epistasis - The essential role of gene interactions in the structure and evolution of genetic systems
    • Phillips, P. C., 2008 Epistasis - the essential role of gene interactions in the structure and evolution of genetic systems. Nat. Rev. Genet. 9: 855–867.
    • (2008) Nat. Rev. Genet , vol.9 , pp. 855-867
    • Phillips, P.C.1
  • 64
    • 66049157487 scopus 로고    scopus 로고
    • Signals of recent positive selection in a worldwide sample of human populations
    • Pickrell, J. K., G. Coop, J. Novembre, S. Kudaravalli, J. Z. Li et al., 2009 Signals of recent positive selection in a worldwide sample of human populations. Genome Res. 19: 826–837.
    • (2009) Genome Res , vol.19 , pp. 826-837
    • Pickrell, J.K.1    Coop, G.2    Novembre, J.3    Kudaravalli, S.4    Li, J.Z.5
  • 65
    • 84954077343 scopus 로고    scopus 로고
    • On the relative roles of background selection and genetic hitchhiking in shaping human cytomegalovirus genetic diversity
    • Renzette, N., T. F. Kowalik, and J. D. Jensen, 2016 On the relative roles of background selection and genetic hitchhiking in shaping human cytomegalovirus genetic diversity. Mol. Ecol. 25: 403–413.
    • (2016) Mol. Ecol , vol.25 , pp. 403-413
    • Renzette, N.1    Kowalik, T.F.2    Jensen, J.D.3
  • 66
    • 84883794892 scopus 로고    scopus 로고
    • Learning natural selection from the site frequency spectrum
    • Ronen, R., N. Udpa, E. Halperin, and V. Bafna, 2013 Learning natural selection from the site frequency spectrum. Genetics 195: 181–193.
    • (2013) Genetics , vol.195 , pp. 181-193
    • Ronen, R.1    Udpa, N.2    Halperin, E.3    Bafna, V.4
  • 67
    • 0034924841 scopus 로고    scopus 로고
    • DNA variation at the rp49 gene region of Drosophila simulans: Evolutionary inferences from an unusual haplotype structure
    • Rozas, J., M. Gullaud, G. Blandin, and M. Aguadé, 2001 DNA variation at the rp49 gene region of Drosophila simulans: evolutionary inferences from an unusual haplotype structure. Genetics 158: 1147–1155.
    • (2001) Genetics , vol.158 , pp. 1147-1155
    • Rozas, J.1    Gullaud, M.2    Blandin, G.3    Aguadé, M.4
  • 68
    • 0037167852 scopus 로고    scopus 로고
    • Detecting recent positive selection in the human genome from haplotype structure
    • Sabeti, P. C., D. E. Reich, J. M. Higgins, H. Z. Levine, D. J. Richter et al., 2002 Detecting recent positive selection in the human genome from haplotype structure. Nature 419: 832–837.
    • (2002) Nature , vol.419 , pp. 832-837
    • Sabeti, P.C.1    Reich, D.E.2    Higgins, J.M.3    Levine, H.Z.4    Richter, D.J.5
  • 69
    • 35349012592 scopus 로고    scopus 로고
    • Genome-wide detection and characterization of positive selection in human populations
    • Sabeti, P. C., P. Varilly, B. Fry, J. Lohmueller, E. Hostetter et al., 2007 Genome-wide detection and characterization of positive selection in human populations. Nature 449: 913–918.
    • (2007) Nature , vol.449 , pp. 913-918
    • Sabeti, P.C.1    Varilly, P.2    Fry, B.3    Lohmueller, J.4    Hostetter, E.5
  • 70
    • 27544497650 scopus 로고    scopus 로고
    • Calibrating a coalescent simulation of human genome sequence variation
    • Schaffner, S. F., C. Foo, S. Gabriel, D. Reich, M. J. Daly et al., 2005 Calibrating a coalescent simulation of human genome sequence variation. Genome Res. 15: 1576–1583.
    • (2005) Genome Res , vol.15 , pp. 1576-1583
    • Schaffner, S.F.1    Foo, C.2    Gabriel, S.3    Reich, D.4    Daly, M.J.5
  • 71
    • 84954052528 scopus 로고    scopus 로고
    • Evaluating the performance of selection scans to detect selective sweeps in domestic dogs
    • Schlamp, F., J. Made, R. Stambler, L. Chesebrough, A. R. Boyko et al., 2016 Evaluating the performance of selection scans to detect selective sweeps in domestic dogs. Mol. Ecol. 25: 342–356.
    • (2016) Mol. Ecol , vol.25 , pp. 342-356
    • Schlamp, F.1    Made, J.2    Stambler, R.3    Chesebrough, L.4    Boyko, A.R.5
  • 72
    • 84923576877 scopus 로고    scopus 로고
    • Cosi2: An efficient simulator of exact and approximate coalescent with selection
    • Shlyakhter, I., P. C. Sabeti, and S. F. Schaffner, 2014 Cosi2: an efficient simulator of exact and approximate coalescent with selection. Bioinformatics 30: 3427–3429.
    • (2014) Bioinformatics , vol.30 , pp. 3427-3429
    • Shlyakhter, I.1    Sabeti, P.C.2    Schaffner, S.F.3
  • 73
    • 0016220238 scopus 로고
    • The hitch-hiking effect of a favourable gene
    • Smith, J. M., and J. Haigh, 1974 The hitch-hiking effect of a favourable gene. Genet. Res. 23: 23–35.
    • (1974) Genet. Res , vol.23 , pp. 23-35
    • Smith, J.M.1    Haigh, J.2
  • 74
    • 33646180401 scopus 로고    scopus 로고
    • The hitchhiking effect on linkage disequilibrium between linked neutral loci
    • Stephan, W., Y. S. Song, and C. H. Langley, 2006 The hitchhiking effect on linkage disequilibrium between linked neutral loci. Genetics 172: 2647–2663.
    • (2006) Genetics , vol.172 , pp. 2647-2663
    • Stephan, W.1    Song, Y.S.2    Langley, C.H.3
  • 75
    • 27544474343 scopus 로고    scopus 로고
    • Recombination and the properties of Tajima’s D in the context of approximate-likelihood calculation
    • Thornton, K., 2005 Recombination and the properties of Tajima’s D in the context of approximate-likelihood calculation. Genetics 171: 2143–2148.
    • (2005) Genetics , vol.171 , pp. 2143-2148
    • Thornton, K.1
  • 76
    • 34247891656 scopus 로고    scopus 로고
    • Controlling the falsepositive rate in multilocus genome scans for selection
    • Thornton, K. R., and J. D. Jensen, 2007 Controlling the falsepositive rate in multilocus genome scans for selection. Genetics 175: 737–750.
    • (2007) Genetics , vol.175 , pp. 737-750
    • Thornton, K.R.1    Jensen, J.D.2
  • 77
    • 84981504235 scopus 로고    scopus 로고
    • Evolution Since Darwin: The First 150 Years, edited by M. A. Bell, D. J. Futuyma, W. F. Eanes, and J. S. Levinton. Sinauer Associates, Sunderland, MA
    • Wakeley, J., 2010 Natural selection and coalescent theory, pp. 119–149 in Evolution Since Darwin: The First 150 Years, edited by M. A. Bell, D. J. Futuyma, W. F. Eanes, and J. S. Levinton. Sinauer Associates, Sunderland, MA.
    • (2010) Natural Selection and Coalescent Theory , pp. 119-149
    • Wakeley, J.1
  • 78
    • 84864258558 scopus 로고    scopus 로고
    • Genome-wide single-cell analysis of recombination activity and de novo mutation rates in human sperm
    • Wang, J., H. C. Fan, B. Behr, and S. R. Quake, 2012 Genome-wide single-cell analysis of recombination activity and de novo mutation rates in human sperm. Cell 150: 402–412.
    • (2012) Cell , vol.150 , pp. 402-412
    • Wang, J.1    Fan, H.C.2    Behr, B.3    Quake, S.R.4


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