OmegaPlus: A scalable tool for rapid detection of selective sweeps in whole-genome datasets

Bioinformatics

Volumn 28, Issue 17, 2012, Pages 2274-2275

  Alachiotis, N ^a   Stamatakis, A ^a   Pavlidis, P ^a  

^a HEIDELBERG INSTITUTE FOR THEORETICAL STUDIES   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOLOGICAL MODEL; COMPUTER PROGRAM; EVOLUTION; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENOME; GENOMICS; METHODOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; SINGLE NUCLEOTIDE POLYMORPHISM;

BASE SEQUENCE; BIOLOGICAL EVOLUTION; GENOME; GENOME-WIDE ASSOCIATION STUDY; GENOMICS; LINKAGE DISEQUILIBRIUM; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; POLYMORPHISM, SINGLE NUCLEOTIDE; SOFTWARE;

EID: 84865553595     PISSN: 13674803     EISSN: 14602059     Source Type: Journal    
DOI: 10.1093/bioinformatics/bts419     Document Type: Article

References (8)

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2. Hudson, R.R. (2002) Generating samples under a wright-fisher neutral model of genetic variation. Bioinformatics, 18, 337-338.
3. Jensen, J.D. et al. (2007) On the utility of linkage disequilibrium as a statistic for identifying targets of positive selection in nonequilibrium populations. Genetics, 176, 2371-2379.
4. Kim, Y. and Nielsen, R. (2004) Linkage disequilibrium as a signature of selective sweeps. Genetics, 167, 1513-1524.
5. Kim, Y. and Stephan, W. (2002) Detecting a local signature of genetic hitchhiking along a recombining chromosome. Genetics, 160, 765-777.
6. Maynard Smith, J. and Haigh, J. (1974) The hitch-hiking effect of a favourable gene. Genet. Res., 23, 23-35.
7. Nielsen, R. et al. (2005) Genomic scans for selective sweeps using SNP data. Genome Res., 15, 1566-1575.
8. Pavlidis, P. et al. (2010) Searching for footprints of positive selection in whole-genome SNP data from nonequilibrium populations. Genetics, 185, 907-922.