Quantitative analysis of tissue distribution of the B16BL6-derived exosomes using a streptavidin-lactadherin fusion protein and Iodine-125-Labeled biotin derivative after intravenous injection in mice

Journal of Pharmaceutical Sciences

Volumn 104, Issue 2, 2015, Pages 705-713

  Morishita, Masaki ^a   Takahashi, Yuki ^a   Nishikawa, Makiya ^a   Sano, Kohei ^a   Kato, Kana ^a   Yamashita, Takuma ^a   Imai, Takafumi ^a   Saji, Hideo ^a   Takakura, Yoshinobu ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Biomaterials; Clearance; Exosome; Lactadherin; Nanoparticles; Pharmacokinetics; Phospholipids; Quantitative analysis; Radioisotope; Streptavidin

Indexed keywords

BIOTIN DERIVATIVE; HYBRID PROTEIN; IODINE 125; LACTADHERIN; LUCIFERASE; PLASMID VECTOR; STREPTAVIDIN; BIOTIN; PROTEIN BINDING; RADIOACTIVE IODINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLADDER; CIRCULATION; CONTROLLED STUDY; EXOSOME; INTESTINE; ISOTOPE LABELING; LIVER; LUNG; MALE; MELANOMA CELL; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; QUANTITATIVE ANALYSIS; RADIOACTIVITY; SPLEEN; TISSUE DISTRIBUTION; ZETA POTENTIAL; ANIMAL; BAGG ALBINO MOUSE; DRUG EFFECTS; EXPERIMENTAL MELANOMA; INTRAVENOUS DRUG ADMINISTRATION; METABOLISM; PHYSIOLOGY;

ANIMALS; BIOTIN; EXOSOMES; INJECTIONS, INTRAVENOUS; IODINE RADIOISOTOPES; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED BALB C; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; STREPTAVIDIN; TISSUE DISTRIBUTION;

EID: 84922895759     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.24251     Document Type: Article

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