메뉴 건너뛰기




Volumn 1861, Issue 11, 2016, Pages 1662-1670

SCD1 deficiency protects mice against ethanol-induced liver injury

Author keywords

Alcoholic fatty liver disease; De novo lipogenesis; Inflammation; SCD1

Indexed keywords

ACYL COENZYME A DESATURASE 1; ALCOHOL; RNA; TRIACYLGLYCEROL; ACYL COENZYME A DESATURASE; FATTY ACID; PROTECTIVE AGENT; SCD1 PROTEIN, MOUSE;

EID: 84981268262     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2016.07.012     Document Type: Article
Times cited : (28)

References (43)
  • 1
    • 84919816311 scopus 로고    scopus 로고
    • New advances in molecular mechanisms and emerging therapeutic targets in alcoholic liver diseases
    • [1] Williams, J.A., Manley, S., Ding, W.X., New advances in molecular mechanisms and emerging therapeutic targets in alcoholic liver diseases. World J. Gastroenterol. 20:36 (2014), 12908–12933.
    • (2014) World J. Gastroenterol. , vol.20 , Issue.36 , pp. 12908-12933
    • Williams, J.A.1    Manley, S.2    Ding, W.X.3
  • 2
    • 73449123375 scopus 로고    scopus 로고
    • Alcoholic liver disease
    • Practice Guideline Committee of the American Association for the Study of Liver D, Practice Parameters Committee of the American College of G
    • [2] O'Shea, R.S., Dasarathy, S., McCullough, A.J., Practice Guideline Committee of the American Association for the Study of Liver D, Practice Parameters Committee of the American College of G, Alcoholic liver disease. Hepatology 51:1 (2010), 307–328.
    • (2010) Hepatology , vol.51 , Issue.1 , pp. 307-328
    • O'Shea, R.S.1    Dasarathy, S.2    McCullough, A.J.3
  • 4
    • 84910646076 scopus 로고    scopus 로고
    • Ethanol and liver: recent insights into the mechanisms of ethanol-induced fatty liver
    • [4] Liu, J., Ethanol and liver: recent insights into the mechanisms of ethanol-induced fatty liver. World J. Gastroenterol. 20:40 (2014), 14672–14685.
    • (2014) World J. Gastroenterol. , vol.20 , Issue.40 , pp. 14672-14685
    • Liu, J.1
  • 5
    • 84864390922 scopus 로고    scopus 로고
    • The epidemiology, pathogenesis and histopathology of fatty liver disease
    • [5] Levene, A.P., Goldin, R.D., The epidemiology, pathogenesis and histopathology of fatty liver disease. Histopathology 61:2 (2012), 141–152.
    • (2012) Histopathology , vol.61 , Issue.2 , pp. 141-152
    • Levene, A.P.1    Goldin, R.D.2
  • 6
    • 0014336420 scopus 로고
    • Anabolic steroid therapy as an adjunct to diet in alcoholic hepatic steatosis
    • [6] Mendenhall, C.L., Anabolic steroid therapy as an adjunct to diet in alcoholic hepatic steatosis. Am. J. Dig. Dis. 13:9 (1968), 783–791.
    • (1968) Am. J. Dig. Dis. , vol.13 , Issue.9 , pp. 783-791
    • Mendenhall, C.L.1
  • 7
    • 0029165057 scopus 로고
    • Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver
    • [7] Teli, M.R., Day, C.P., Burt, A.D., Bennett, M.K., James OF, Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver. Lancet 346:8981 (1995), 987–990.
    • (1995) Lancet , vol.346 , Issue.8981 , pp. 987-990
    • Teli, M.R.1    Day, C.P.2    Burt, A.D.3    Bennett, M.K.4    James OF5
  • 8
    • 0021173477 scopus 로고
    • Prospective evaluation of alcohol abuse and alcoholic liver injury in men as predictors of development of cirrhosis
    • [8] Sorensen, T.I., Orholm, M., Bentsen, K.D., Hoybye, G., Eghoje, K., Christoffersen, P., Prospective evaluation of alcohol abuse and alcoholic liver injury in men as predictors of development of cirrhosis. Lancet 2:8397 (1984), 241–244.
    • (1984) Lancet , vol.2 , Issue.8397 , pp. 241-244
    • Sorensen, T.I.1    Orholm, M.2    Bentsen, K.D.3    Hoybye, G.4    Eghoje, K.5    Christoffersen, P.6
  • 9
    • 39849096127 scopus 로고    scopus 로고
    • Alcohol induced hepatic fibrosis: role of acetaldehyde
    • [9] Mello, T., Ceni, E., Surrenti, C., Galli, A., Alcohol induced hepatic fibrosis: role of acetaldehyde. Mol. Asp. Med. 29:1–2 (2008), 17–21.
    • (2008) Mol. Asp. Med. , vol.29 , Issue.1-2 , pp. 17-21
    • Mello, T.1    Ceni, E.2    Surrenti, C.3    Galli, A.4
  • 11
    • 84926420371 scopus 로고    scopus 로고
    • Alcoholic liver disease: mechanisms of injury and targeted treatment
    • [11] Louvet, A., Mathurin, P., Alcoholic liver disease: mechanisms of injury and targeted treatment. Nat. Rev. Gastroenterol. Hepatol. 12:4 (2015), 231–242.
    • (2015) Nat. Rev. Gastroenterol. Hepatol. , vol.12 , Issue.4 , pp. 231-242
    • Louvet, A.1    Mathurin, P.2
  • 12
    • 0037047284 scopus 로고    scopus 로고
    • Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP)
    • [12] You, M., Fischer, M., Deeg, M.A., Crabb, D.W., Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP). J. Biol. Chem. 277:32 (2002), 29342–29347.
    • (2002) J. Biol. Chem. , vol.277 , Issue.32 , pp. 29342-29347
    • You, M.1    Fischer, M.2    Deeg, M.A.3    Crabb, D.W.4
  • 13
    • 77952863834 scopus 로고    scopus 로고
    • Genetic control of de novo lipogenesis: role in diet-induced obesity
    • [13] Strable, M.S., Ntambi, J.M., Genetic control of de novo lipogenesis: role in diet-induced obesity. Crit. Rev. Biochem. Mol. Biol. 45:3 (2010), 199–214.
    • (2010) Crit. Rev. Biochem. Mol. Biol. , vol.45 , Issue.3 , pp. 199-214
    • Strable, M.S.1    Ntambi, J.M.2
  • 14
    • 0035978425 scopus 로고    scopus 로고
    • Production of acetate in the liver and its utilization in peripheral tissues
    • [14] Yamashita, H., Kaneyuki, T., Tagawa, K., Production of acetate in the liver and its utilization in peripheral tissues. Biochim. Biophys. Acta 1532:1–2 (2001), 79–87.
    • (2001) Biochim. Biophys. Acta , vol.1532 , Issue.1-2 , pp. 79-87
    • Yamashita, H.1    Kaneyuki, T.2    Tagawa, K.3
  • 15
    • 0034676629 scopus 로고    scopus 로고
    • Cytokines in alcoholic and nonalcoholic steatohepatitis
    • [15] Tilg, H., Diehl, A.M., Cytokines in alcoholic and nonalcoholic steatohepatitis. N. Engl. J. Med. 343:20 (2000), 1467–1476.
    • (2000) N. Engl. J. Med. , vol.343 , Issue.20 , pp. 1467-1476
    • Tilg, H.1    Diehl, A.M.2
  • 16
    • 0037067570 scopus 로고    scopus 로고
    • Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss
    • [16] Cohen, P., Miyazaki, M., Socci, N.D., Hagge-Greenberg, A., Liedtke, W., Soukas, A.A., et al. Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss. Science 297:5579 (2002), 240–243.
    • (2002) Science , vol.297 , Issue.5579 , pp. 240-243
    • Cohen, P.1    Miyazaki, M.2    Socci, N.D.3    Hagge-Greenberg, A.4    Liedtke, W.5    Soukas, A.A.6
  • 17
    • 78149284997 scopus 로고    scopus 로고
    • Role of hepatic desaturases in obesity-related metabolic disorders
    • [17] Bjermo, H., Riserus, U., Role of hepatic desaturases in obesity-related metabolic disorders. Curr. Opin. Clin. Nutr. Metab. Care 13:6 (2010), 703–708.
    • (2010) Curr. Opin. Clin. Nutr. Metab. Care , vol.13 , Issue.6 , pp. 703-708
    • Bjermo, H.1    Riserus, U.2
  • 19
    • 38049169032 scopus 로고    scopus 로고
    • Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice
    • [19] MacDonald, M.L., Singaraja, R.R., Bissada, N., Ruddle, P., Watts, R., Karasinska, J.M., et al. Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice. J. Lipid Res. 49:1 (2008), 217–229.
    • (2008) J. Lipid Res. , vol.49 , Issue.1 , pp. 217-229
    • MacDonald, M.L.1    Singaraja, R.R.2    Bissada, N.3    Ruddle, P.4    Watts, R.5    Karasinska, J.M.6
  • 20
    • 84875160269 scopus 로고    scopus 로고
    • Mouse model of chronic and binge ethanol feeding (the NIAAA model)
    • [20] Bertola, A., Mathews, S., Ki, S.H., Wang, H., Gao, B., Mouse model of chronic and binge ethanol feeding (the NIAAA model). Nat. Protoc. 8:3 (2013), 627–637.
    • (2013) Nat. Protoc. , vol.8 , Issue.3 , pp. 627-637
    • Bertola, A.1    Mathews, S.2    Ki, S.H.3    Wang, H.4    Gao, B.5
  • 21
    • 77957946415 scopus 로고    scopus 로고
    • Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: role of signal transducer and activator of transcription 3
    • [21] Ki, S.H., Park, O., Zheng, M., Morales-Ibanez, O., Kolls, J.K., Bataller, R., et al. Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: role of signal transducer and activator of transcription 3. Hepatology 52:4 (2010), 1291–1300.
    • (2010) Hepatology , vol.52 , Issue.4 , pp. 1291-1300
    • Ki, S.H.1    Park, O.2    Zheng, M.3    Morales-Ibanez, O.4    Kolls, J.K.5    Bataller, R.6
  • 23
    • 80054872790 scopus 로고    scopus 로고
    • Alcoholic liver disease: pathogenesis and new therapeutic targets
    • [23] Gao, B., Bataller, R., Alcoholic liver disease: pathogenesis and new therapeutic targets. Gastroenterology 141:5 (2011), 1572–1585.
    • (2011) Gastroenterology , vol.141 , Issue.5 , pp. 1572-1585
    • Gao, B.1    Bataller, R.2
  • 24
    • 9644290860 scopus 로고    scopus 로고
    • The role of AMP-activated protein kinase in the action of ethanol in the liver
    • [24] You, M., Matsumoto, M., Pacold, C.M., Cho, W.K., Crabb, D.W., The role of AMP-activated protein kinase in the action of ethanol in the liver. Gastroenterology 127:6 (2004), 1798–1808.
    • (2004) Gastroenterology , vol.127 , Issue.6 , pp. 1798-1808
    • You, M.1    Matsumoto, M.2    Pacold, C.M.3    Cho, W.K.4    Crabb, D.W.5
  • 25
    • 81255157754 scopus 로고    scopus 로고
    • Inhibition of stearoyl-CoA desaturase1 activates AMPK and exhibits beneficial lipid metabolic effects in vitro
    • [25] Kim, E., Lee, J.H., Ntambi, J.M., Hyun, C.K., Inhibition of stearoyl-CoA desaturase1 activates AMPK and exhibits beneficial lipid metabolic effects in vitro. Eur. J. Pharmacol. 672:1–3 (2011), 38–44.
    • (2011) Eur. J. Pharmacol. , vol.672 , Issue.1-3 , pp. 38-44
    • Kim, E.1    Lee, J.H.2    Ntambi, J.M.3    Hyun, C.K.4
  • 26
    • 2942588527 scopus 로고    scopus 로고
    • Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element-binding protein-1c-dependent and -independent mechanisms
    • [26] Miyazaki, M., Dobrzyn, A., Man, W.C., Chu, K., Sampath, H., Kim, H.J., et al. Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element-binding protein-1c-dependent and -independent mechanisms. J. Biol. Chem. 279:24 (2004), 25164–25171.
    • (2004) J. Biol. Chem. , vol.279 , Issue.24 , pp. 25164-25171
    • Miyazaki, M.1    Dobrzyn, A.2    Man, W.C.3    Chu, K.4    Sampath, H.5    Kim, H.J.6
  • 27
    • 36448991861 scopus 로고    scopus 로고
    • Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis
    • [27] Miyazaki, M., Flowers, M.T., Sampath, H., Chu, K., Otzelberger, C., Liu, X., et al. Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis. Cell Metab. 6:6 (2007), 484–496.
    • (2007) Cell Metab. , vol.6 , Issue.6 , pp. 484-496
    • Miyazaki, M.1    Flowers, M.T.2    Sampath, H.3    Chu, K.4    Otzelberger, C.5    Liu, X.6
  • 28
    • 0021262496 scopus 로고
    • Alcohol ingestion and levels of hepatic fatty acid synthetase and stearoyl-CoA desaturase activities in rats
    • [28] Rao, G.A., Lew, G., Larkin, E.C., Alcohol ingestion and levels of hepatic fatty acid synthetase and stearoyl-CoA desaturase activities in rats. Lipids 19:2 (1984), 151–153.
    • (1984) Lipids , vol.19 , Issue.2 , pp. 151-153
    • Rao, G.A.1    Lew, G.2    Larkin, E.C.3
  • 29
    • 0028179957 scopus 로고
    • Selective reduction of delta 6 and delta 5 desaturase activities but not delta 9 desaturase in micropigs chronically fed ethanol
    • [29] Nakamura, M.T., Tang, A.B., Villanueva, J., Halsted, C.H., Phinney, S.D., Selective reduction of delta 6 and delta 5 desaturase activities but not delta 9 desaturase in micropigs chronically fed ethanol. J. Clin. Invest. 93:1 (1994), 450–454.
    • (1994) J. Clin. Invest. , vol.93 , Issue.1 , pp. 450-454
    • Nakamura, M.T.1    Tang, A.B.2    Villanueva, J.3    Halsted, C.H.4    Phinney, S.D.5
  • 30
    • 12744250305 scopus 로고    scopus 로고
    • Perspectives on alcohol consumption: liver polyunsaturated fatty acids and essential fatty acid metabolism
    • [30] Pawlosky, R.J., Salem, N. Jr., Perspectives on alcohol consumption: liver polyunsaturated fatty acids and essential fatty acid metabolism. Alcohol 34:1 (2004), 27–33.
    • (2004) Alcohol , vol.34 , Issue.1 , pp. 27-33
    • Pawlosky, R.J.1    Salem, N.2
  • 31
    • 0034190215 scopus 로고    scopus 로고
    • Metabolism of some radiolabeled essential fatty acids in isolated rat hepatocytes is affected by dietary ethanol
    • [31] Retterstol, K., Lund, A.M., Tverdal, S., Cristophersen, B.O., Metabolism of some radiolabeled essential fatty acids in isolated rat hepatocytes is affected by dietary ethanol. Alcohol 21:1 (2000), 19–26.
    • (2000) Alcohol , vol.21 , Issue.1 , pp. 19-26
    • Retterstol, K.1    Lund, A.M.2    Tverdal, S.3    Cristophersen, B.O.4
  • 32
    • 77649335848 scopus 로고    scopus 로고
    • Serum fatty acid composition and insulin resistance are independently associated with liver fat markers in elderly men
    • [32] Petersson, H., Arnlov, J., Zethelius, B., Riserus, U., Serum fatty acid composition and insulin resistance are independently associated with liver fat markers in elderly men. Diabetes Res. Clin. Pract. 87:3 (2010), 379–384.
    • (2010) Diabetes Res. Clin. Pract. , vol.87 , Issue.3 , pp. 379-384
    • Petersson, H.1    Arnlov, J.2    Zethelius, B.3    Riserus, U.4
  • 33
    • 0037523216 scopus 로고    scopus 로고
    • Hepatic expression of PPARalpha, a molecular target of fibrates, is regulated during inflammation in a gender-specific manner
    • [33] Tai, E.S., bin Ali, A., Zhang, Q., LM, L., CE, T., Retnam, L., et al. Hepatic expression of PPARalpha, a molecular target of fibrates, is regulated during inflammation in a gender-specific manner. FEBS Lett. 546:2–3 (2003), 237–240.
    • (2003) FEBS Lett. , vol.546 , Issue.2-3 , pp. 237-240
    • Tai, E.S.1    bin Ali, A.2    Zhang, Q.3    LM, L.4    CE, T.5    Retnam, L.6
  • 34
    • 81555209601 scopus 로고    scopus 로고
    • Stearoyl CoA desaturase 1: role in cellular inflammation and stress
    • [34] Liu, X., Strable, M.S., Ntambi, J.M., Stearoyl CoA desaturase 1: role in cellular inflammation and stress. Adv. Nutr. 2:1 (2011), 15–22.
    • (2011) Adv. Nutr. , vol.2 , Issue.1 , pp. 15-22
    • Liu, X.1    Strable, M.S.2    Ntambi, J.M.3
  • 36
    • 12744266543 scopus 로고    scopus 로고
    • Role of different dietary fatty acids in the pathogenesis of experimental alcoholic liver disease
    • [36] Nanji, A.A., Role of different dietary fatty acids in the pathogenesis of experimental alcoholic liver disease. Alcohol 34:1 (2004), 21–25.
    • (2004) Alcohol , vol.34 , Issue.1 , pp. 21-25
    • Nanji, A.A.1
  • 37
    • 1842425830 scopus 로고    scopus 로고
    • Dietary saturated fat reduces alcoholic hepatotoxicity in rats by altering fatty acid metabolism and membrane composition
    • [37] Ronis, M.J., Korourian, S., Zipperman, M., Hakkak, R., Badger, T.M., Dietary saturated fat reduces alcoholic hepatotoxicity in rats by altering fatty acid metabolism and membrane composition. J. Nutr. 134:4 (2004), 904–912.
    • (2004) J. Nutr. , vol.134 , Issue.4 , pp. 904-912
    • Ronis, M.J.1    Korourian, S.2    Zipperman, M.3    Hakkak, R.4    Badger, T.M.5
  • 38
    • 84922630906 scopus 로고    scopus 로고
    • Supplementation of saturated long-chain fatty acids maintains intestinal eubiosis and reduces ethanol-induced liver injury in mice
    • e16
    • [38] Chen, P., Torralba, M., Tan, J., Embree, M., Zengler, K., Starkel, P., et al. Supplementation of saturated long-chain fatty acids maintains intestinal eubiosis and reduces ethanol-induced liver injury in mice. Gastroenterology 148:1 (2015), 203–214 e16.
    • (2015) Gastroenterology , vol.148 , Issue.1 , pp. 203-214
    • Chen, P.1    Torralba, M.2    Tan, J.3    Embree, M.4    Zengler, K.5    Starkel, P.6
  • 39
    • 40449093056 scopus 로고    scopus 로고
    • Mammalian sirtuin 1 is involved in the protective action of dietary saturated fat against alcoholic fatty liver in mice
    • [39] You, M., Cao, Q., Liang, X., Ajmo, J.M., Ness, G.C., Mammalian sirtuin 1 is involved in the protective action of dietary saturated fat against alcoholic fatty liver in mice. J. Nutr. 138:3 (2008), 497–501.
    • (2008) J. Nutr. , vol.138 , Issue.3 , pp. 497-501
    • You, M.1    Cao, Q.2    Liang, X.3    Ajmo, J.M.4    Ness, G.C.5
  • 40
    • 84903207987 scopus 로고    scopus 로고
    • Overfeeding polyunsaturated and saturated fat causes distinct effects on liver and visceral fat accumulation in humans
    • [40] Rosqvist, F., Iggman, D., Kullberg, J., Cedernaes, J., Johansson, H.E., Larsson, A., et al. Overfeeding polyunsaturated and saturated fat causes distinct effects on liver and visceral fat accumulation in humans. Diabetes 63:7 (2014), 2356–2368.
    • (2014) Diabetes , vol.63 , Issue.7 , pp. 2356-2368
    • Rosqvist, F.1    Iggman, D.2    Kullberg, J.3    Cedernaes, J.4    Johansson, H.E.5    Larsson, A.6
  • 41
    • 0026042412 scopus 로고
    • Hepatic, metabolic and toxic effects of ethanol: 1991 update
    • [41] Lieber, C.S., Hepatic, metabolic and toxic effects of ethanol: 1991 update. Alcohol. Clin. Exp. Res. 15:4 (1991), 573–592.
    • (1991) Alcohol. Clin. Exp. Res. , vol.15 , Issue.4 , pp. 573-592
    • Lieber, C.S.1
  • 42
    • 57649214103 scopus 로고    scopus 로고
    • Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)
    • [42] Musso, G., Gambino, R., Cassader, M., Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD). Prog. Lipid Res. 48:1 (2009), 1–26.
    • (2009) Prog. Lipid Res. , vol.48 , Issue.1 , pp. 1-26
    • Musso, G.1    Gambino, R.2    Cassader, M.3
  • 43
    • 84898439031 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: molecular mechanisms for the hepatic steatosis
    • [43] Koo, S.H., Nonalcoholic fatty liver disease: molecular mechanisms for the hepatic steatosis. Clin. Mol. Hepatol. 19:3 (2013), 210–215.
    • (2013) Clin. Mol. Hepatol. , vol.19 , Issue.3 , pp. 210-215
    • Koo, S.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.