Vagal nerve stimulation improves mitochondrial dynamics via an M3 receptor/CaMKKβ/AMPK pathway in isoproterenol-induced myocardial ischaemia

Journal of Cellular and Molecular Medicine

Volumn 21, Issue 1, 2017, Pages 58-71

  Xue, Run Qing ^a   Sun, Lei ^a   Yu, Xiao Jiang ^a   Li, Dong Ling ^a   Zang, Wei Jin ^a  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

AMP activated protein kinase; cardioprotection; mitochondrial dynamics; mitochondrial function; myocardial ischaemia; subtype 3 of muscarinic acetylcholine receptor; vagal nerve stimulation

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MITOFUSIN 1; MUSCARINIC M3 RECEPTOR; CARRIER PROTEIN; ISOPRENALINE;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ELECTROCARDIOGRAPHY; ENZYME ACTIVITY; FLOW CYTOMETRY; GENE TARGETING; HEART INFARCTION SIZE; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEMODYNAMICS; ISOPROTERENOL-INDUCED MYOCARDIAL INFARCTION; MALE; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OPTIC NERVE ATROPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; TRANSMISSION ELECTRON MICROSCOPY; VAGUS NERVE STIMULATION; WESTERN BLOTTING; ANIMAL; APOPTOSIS; CHEMICALLY INDUCED; DRUG EFFECTS; HEART INFARCTION; HEART MITOCHONDRION; HEART MUSCLE ISCHEMIA; METABOLISM; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; PHOSPHORYLATION; PHYSIOLOGY; PROCEDURES; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; APOPTOSIS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE; ISOPROTERENOL; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA, HEART; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, MUSCARINIC M3; SIGNAL TRANSDUCTION; VAGUS NERVE STIMULATION;

EID: 84980383736     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.12938     Document Type: Article

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