Vagus nerve stimulation initiated late during ischemia, but not reperfusion, exerts cardioprotection via amelioration of cardiac mitochondrial dysfunction

Heart Rhythm

Volumn 11, Issue 12, 2014, Pages 2278-2287

  Shinlapawittayatorn, Krekwit ^a   Chinda, Kroekkiat ^a   Palee, Siripong ^a   Surinkaew, Sirirat ^a   Kumfu, Sirinart ^a   Kumphune, Sarawut ^a   Chattipakorn, Siriporn ^a   Kenknight, Bruce H ^b   Chattipakorn, Nipon ^a  

^a CHIANG MAI UNIVERSITY   (Thailand)

^b Cyberonics Inc   (Italy)

Author keywords

Acetylcholine; Cardioprotection; Heart; Ischemic reperfusion injury; Vagus nerve stimulation

Indexed keywords

ATROPINE; CONNEXIN 43; CYTOCHROME C; INTERLEUKIN 4; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIAC MITOCHONDRIAL DYSFUNCTION; CONTROLLED STUDY; CORONARY ARTERY OCCLUSION; DEPOLARIZATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; EXPERIMENTAL VENTRICULAR FIBRILLATION; HEART DISEASE; HEART FUNCTION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; HEART VENTRICLE FIBRILLATION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; NONHUMAN; REPERFUSION INJURY; SWELLING; SWINE; VAGUS NERVE STIMULATION; ANIMAL; COMPARATIVE STUDY; DISEASE MODEL; ELECTROCARDIOGRAPHY; HEART LEFT VENTRICLE FUNCTION; HEART MITOCHONDRION; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PIG; PROCEDURES; RANDOMIZATION; REFERENCE VALUE; RISK ASSESSMENT; TREATMENT OUTCOME; ULTRASTRUCTURE;

ANIMALS; ATROPINE; DISEASE MODELS, ANIMAL; ELECTROCARDIOGRAPHY; MITOCHONDRIA, HEART; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; RANDOM ALLOCATION; REFERENCE VALUES; RISK ASSESSMENT; SWINE; TREATMENT OUTCOME; VAGUS NERVE STIMULATION; VENTRICULAR FUNCTION, LEFT;

EID: 84919383950     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2014.08.001     Document Type: Article

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