메뉴 건너뛰기




Volumn 244, Issue , 2016, Pages 159-168

Thymol, a dietary monoterpene phenol abrogates mitochondrial dysfunction in β-adrenergic agonist induced myocardial infarcted rats by inhibiting oxidative stress

Author keywords

Calcium uniporter malfunction; Isoproterenol; Mitochondrial dysfunction; Mitochondrial swelling; Oxidative stress; Thymol

Indexed keywords

2 OXOGLUTARIC ACID; ADENOSINE TRIPHOSPHATE; CATALASE; CYTOCHROME C OXIDASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; ISOCITRATE DEHYDROGENASE; ISOCITRIC ACID; ISOPRENALINE; MALATE DEHYDROGENASE; MALIC ACID; OXOGLUTARATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SUPEROXIDE DISMUTASE; THYMOL; BETA ADRENERGIC RECEPTOR STIMULATING AGENT;

EID: 84951780285     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2015.12.006     Document Type: Article
Times cited : (53)

References (55)
  • 2
    • 84922381210 scopus 로고    scopus 로고
    • Heart disease and Stroke Statistics-2015 update: A report from American Heart Association
    • A.S. Go, and et al. American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and Stroke Statistics-2015 update: a report from American Heart Association Circulation 131 2015 e29 e322
    • (2015) Circulation , vol.131 , pp. e29-e322
    • Go, A.S.1
  • 3
    • 84856286836 scopus 로고    scopus 로고
    • Preventive effects of N-acetyl cysteine on lipids, lipoproteins and myocardial infarct size in isoproterenol induced myocardial infarcted rats: An in vivo and in vitro study
    • M.F. Nagoor Meeran, P.S.M. Prince, and R. Hidhayath Basha Preventive effects of N-acetyl cysteine on lipids, lipoproteins and myocardial infarct size in isoproterenol induced myocardial infarcted rats: an in vivo and in vitro study Eur. J. Pharmacol. 677 2012 116 122
    • (2012) Eur. J. Pharmacol. , vol.677 , pp. 116-122
    • Nagoor Meeran, M.F.1    Prince, P.S.M.2    Hidhayath Basha, R.3
  • 4
    • 79960346334 scopus 로고    scopus 로고
    • Compartmentalization of β-adrenergic signals in cardiomyocytes
    • Y.K. Xiang Compartmentalization of β-adrenergic signals in cardiomyocytes Circ. Res. 109 2011 231 244
    • (2011) Circ. Res. , vol.109 , pp. 231-244
    • Xiang, Y.K.1
  • 6
    • 84961398142 scopus 로고    scopus 로고
    • Protective effects of 7-hydroxycoumarin on dyslipidemia and cardiac hypertrophy in isoproterenol induced myocardial infarction in rats
    • jbt21770
    • G.S. Jagadeesh, M.F. Nagoor Meeran, and P. Selvaraj Protective effects of 7-hydroxycoumarin on dyslipidemia and cardiac hypertrophy in isoproterenol induced myocardial infarction in rats J. Biochem. Mol. Toxicol. 2015 doi: jbt21770
    • (2015) J. Biochem. Mol. Toxicol.
    • Jagadeesh, G.S.1    Nagoor Meeran, M.F.2    Selvaraj, P.3
  • 7
    • 66949139996 scopus 로고    scopus 로고
    • Mitochondrial biogenesis in cardiac pathophysiology
    • S. Rimbaud, A. Garnier, and R. Ventura-Clapier Mitochondrial biogenesis in cardiac pathophysiology Pharmacol. Rep. 61 2009 131 138
    • (2009) Pharmacol. Rep. , vol.61 , pp. 131-138
    • Rimbaud, S.1    Garnier, A.2    Ventura-Clapier, R.3
  • 8
    • 84855559900 scopus 로고    scopus 로고
    • Ellagic acid protects mitochondria from β-adrenergic agonist induced myocardial damage in rats; Evidence from in vivo, in vitro and ultra structural study
    • M. Mari Kannan, and S.D. Quine Ellagic acid protects mitochondria from β-adrenergic agonist induced myocardial damage in rats; evidence from in vivo, in vitro and ultra structural study Food Res. Int. 45 2012 1 8
    • (2012) Food Res. Int. , vol.45 , pp. 1-8
    • Mari Kannan, M.1    Quine, S.D.2
  • 9
    • 77952270920 scopus 로고    scopus 로고
    • Cardiovascular friendly natural products: A promising approach in the management of CVD
    • S.K. Shukla, S. Gupta, S.K. Ojha, and S.B. Sharma Cardiovascular friendly natural products: a promising approach in the management of CVD Nat. Prod. Res. 24 2010 873 898
    • (2010) Nat. Prod. Res. , vol.24 , pp. 873-898
    • Shukla, S.K.1    Gupta, S.2    Ojha, S.K.3    Sharma, S.B.4
  • 10
    • 84899754146 scopus 로고    scopus 로고
    • Protective effect of Boerhaavia diffusa L. against mitochondrial dysfunction in angiotensin II induced hypertrophy in H9c2 cardiomyoblast cells
    • A. Prathapan, V.P. Vineetha, and K.G. Raghu Protective effect of Boerhaavia diffusa L. against mitochondrial dysfunction in angiotensin II induced hypertrophy in H9c2 cardiomyoblast cells PLoS One 9 4 2014 e96220 10.1371/journal.pone.0096220
    • (2014) PLoS One , vol.9 , Issue.4
    • Prathapan, A.1    Vineetha, V.P.2    Raghu, K.G.3
  • 11
    • 84929590028 scopus 로고    scopus 로고
    • Catecholamine toxicity triggers myocardial membrane destabilization in rats: Thymol and its counter action
    • M.F. Nagoor Meeran, G.S. Jagadeesh, and P. Selvaraj Catecholamine toxicity triggers myocardial membrane destabilization in rats: thymol and its counter action RSC Adv. 5 2015 4338
    • (2015) RSC Adv. , vol.5 , pp. 4338
    • Nagoor Meeran, M.F.1    Jagadeesh, G.S.2    Selvaraj, P.3
  • 12
    • 84924599481 scopus 로고    scopus 로고
    • Thymol attenuates inflammation in isoproterenol induced myocardial infarcted rats by inhibiting the release of lysosome enzymes and downregulating the expressions of proinflammatory cytokines
    • M.F. Nagoor Meeran, G.S. Jagadeesh, and P. Selvaraj Thymol attenuates inflammation in isoproterenol induced myocardial infarcted rats by inhibiting the release of lysosome enzymes and downregulating the expressions of proinflammatory cytokines Eur. J. Pharmacol. 754 2015 153 161
    • (2015) Eur. J. Pharmacol. , vol.754 , pp. 153-161
    • Nagoor Meeran, M.F.1    Jagadeesh, G.S.2    Selvaraj, P.3
  • 13
    • 84866454503 scopus 로고    scopus 로고
    • Protective effects of thymol on altered lipid peroxidation products and non-enzymatic antioxidants in isoproterenol induced myocardial infarcted rats
    • M.F. Nagoor Meeran, and P. Stanely Mainzen Prince Protective effects of thymol on altered lipid peroxidation products and non-enzymatic antioxidants in isoproterenol induced myocardial infarcted rats J. Biochem. Mol. Toxicol. 26 2012 368 373
    • (2012) J. Biochem. Mol. Toxicol. , vol.26 , pp. 368-373
    • Nagoor Meeran, M.F.1    Stanely Mainzen Prince, P.2
  • 15
    • 84863998533 scopus 로고    scopus 로고
    • Protective effects of N-acetyl cysteine on membrane-bound adenosine triphosphatases and minerals in isoproterenol-induced myocardial-infarcted rats: An in vivo and in vitro study
    • M.F. Nagoor Meeran, and P. Stanely Mainzen Prince Protective effects of N-acetyl cysteine on membrane-bound adenosine triphosphatases and minerals in isoproterenol-induced myocardial-infarcted rats: an in vivo and in vitro study J. Biochem. Mol. Toxicol. 26 2012 276 281
    • (2012) J. Biochem. Mol. Toxicol. , vol.26 , pp. 276-281
    • Nagoor Meeran, M.F.1    Stanely Mainzen Prince, P.2
  • 16
    • 79958864961 scopus 로고    scopus 로고
    • Protective effects of N-acetyl cysteine on lipid peroxide metabolism on isoproterenol-induced myocardial infarcted rats
    • M.F. Nagoor Meeran, and P. Stanely Mainzen Prince Protective effects of N-acetyl cysteine on lipid peroxide metabolism on isoproterenol-induced myocardial infarcted rats J. Biochem. Mol. Toxicol. 25 2011 151 157
    • (2011) J. Biochem. Mol. Toxicol. , vol.25 , pp. 151-157
    • Nagoor Meeran, M.F.1    Stanely Mainzen Prince, P.2
  • 18
    • 0023915949 scopus 로고
    • Lipid peroxidation measured as thiobarbituric acid-reactive substances in tissue slices: Characterization and comparison with homogenates and microsomes
    • C.G. Fraga, B.E. Leibovitz, and A.L. Toppel Lipid peroxidation measured as thiobarbituric acid-reactive substances in tissue slices: characterization and comparison with homogenates and microsomes Free Radic. Biol. Med. 4 1988 155 161
    • (1988) Free Radic. Biol. Med. , vol.4 , pp. 155-161
    • Fraga, C.G.1    Leibovitz, B.E.2    Toppel, A.L.3
  • 19
    • 0026632930 scopus 로고
    • Ferrous ion oxidation in the presence of xylenol orange for detection of lipid hydroperoxide in low density lipoprotein
    • Z.Y. Jiang, J.V. Hunt, and S.P. Wolff Ferrous ion oxidation in the presence of xylenol orange for detection of lipid hydroperoxide in low density lipoprotein Anal. Biochem. 202 1992 384 389
    • (1992) Anal. Biochem. , vol.202 , pp. 384-389
    • Jiang, Z.Y.1    Hunt, J.V.2    Wolff, S.P.3
  • 20
    • 0021681627 scopus 로고
    • A modified spectrophotometric assay of superoxide dismutase
    • P. Kakkar, B. Das, and P.N. Viswanathan A modified spectrophotometric assay of superoxide dismutase Ind. J. Biochem. Biophys. 21 1984 130 132
    • (1984) Ind. J. Biochem. Biophys. , vol.21 , pp. 130-132
    • Kakkar, P.1    Das, B.2    Viswanathan, P.N.3
  • 21
    • 0015353270 scopus 로고
    • Colorimetric assay of catalase
    • A.K. Sinha Colorimetric assay of catalase Anal. Biochem. 47 1972 389 394
    • (1972) Anal. Biochem. , vol.47 , pp. 389-394
    • Sinha, A.K.1
  • 24
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipids from animal tissues
    • J. Folch, M. Lees, and G.H. Sloane Stanley A simple method for the isolation and purification of total lipids from animal tissues J. Biol. Chem. 226 1957 497 509
    • (1957) J. Biol. Chem. , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 25
    • 50449112322 scopus 로고
    • A new method for the direct determination of serum cholesterol
    • A. Zlatkis, B. Zak, and A.L. Boyle A new method for the direct determination of serum cholesterol J. Lab. Clin. Med. 41 1953 486 492
    • (1953) J. Lab. Clin. Med. , vol.41 , pp. 486-492
    • Zlatkis, A.1    Zak, B.2    Boyle, A.L.3
  • 26
    • 0015849889 scopus 로고
    • An easy colorimetric micromethod for routine determination of free fatty acids in plasma
    • K. Falholt, B. Lund, and W. Falholt An easy colorimetric micromethod for routine determination of free fatty acids in plasma Clin. Chim. Acta 46 1973 105 111
    • (1973) Clin. Chim. Acta , vol.46 , pp. 105-111
    • Falholt, K.1    Lund, B.2    Falholt, W.3
  • 27
    • 0019949179 scopus 로고
    • Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide
    • P. Fossati, and L. Prencipe Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide Clin. Chem. 28 1982 2077 2080
    • (1982) Clin. Chem. , vol.28 , pp. 2077-2080
    • Fossati, P.1    Prencipe, L.2
  • 28
    • 6544234261 scopus 로고
    • Microdetermination of plasma phospholipids by trichloroacetic acid precipitation
    • D.B. Zilversmit, and A.K. Davis Microdetermination of plasma phospholipids by trichloroacetic acid precipitation J. Lab. Clin. Med. 35 1950 155 160
    • (1950) J. Lab. Clin. Med. , vol.35 , pp. 155-160
    • Zilversmit, D.B.1    Davis, A.K.2
  • 29
    • 0002794972 scopus 로고
    • Isocitrate dehydrogenase
    • J.C. King, D. Van, Nostrand Co London
    • J. King Isocitrate dehydrogenase J.C. King, D. Van, Practical Clinical Enzymology 1965 Nostrand Co London 363
    • (1965) Practical Clinical Enzymology , pp. 363
    • King, J.1
  • 30
    • 84957841390 scopus 로고
    • The enzymatic mechanism of oxidation-reductions between malate or isocitrate and pyruvate
    • A.H. Mehler, A. Kornberg, S. Grisolia, and S. Ochoa The enzymatic mechanism of oxidation-reductions between malate or isocitrate and pyruvate J. Biol. Chem. 174 1948 961 977
    • (1948) J. Biol. Chem. , vol.174 , pp. 961-977
    • Mehler, A.H.1    Kornberg, A.2    Grisolia, S.3    Ochoa, S.4
  • 31
    • 77956995420 scopus 로고
    • α-Ketoglutarate dehydrogenase complex from Escherichia coli
    • J.M. Lowenstein, Academic Press London
    • L.J. Reed, and R.B. Mukherjee α-Ketoglutarate dehydrogenase complex from Escherichia coli J.M. Lowenstein, Methods in Enzymology 1969 Academic Press London 53 61
    • (1969) Methods in Enzymology , pp. 53-61
    • Reed, L.J.1    Mukherjee, R.B.2
  • 32
    • 73649196367 scopus 로고
    • Studies on the respiratory chain-linked dihydrodiphosphopyridine nucleotide dehydrogenase. I. Assay of the enzyme in particulate and in soluble preparations
    • S. Minakami, R.L. Ringler, and T.P. Singer Studies on the respiratory chain-linked dihydrodiphosphopyridine nucleotide dehydrogenase. I. Assay of the enzyme in particulate and in soluble preparations J. Biol. Chem. 237 1962 569 576
    • (1962) J. Biol. Chem. , vol.237 , pp. 569-576
    • Minakami, S.1    Ringler, R.L.2    Singer, T.P.3
  • 33
    • 0001732361 scopus 로고
    • Microdetermination of cytochrome oxidase in rat tissues by the oxidation on N-phenyl-p-phenylenediamine or ascorbic acid
    • W. Pearl, J. Cascarano, and B.W. Zweifach Microdetermination of cytochrome oxidase in rat tissues by the oxidation on N-phenyl-p-phenylenediamine or ascorbic acid J. Histochem. Cytochem. 11 1963 102 104
    • (1963) J. Histochem. Cytochem. , vol.11 , pp. 102-104
    • Pearl, W.1    Cascarano, J.2    Zweifach, B.W.3
  • 34
    • 0000264190 scopus 로고
    • Assay of intermediates of the citric acid cycle and related compounds by flourimetric enzymatic methods
    • J.M. Lowenstein, Academic Press New York
    • J.R. Williams, and B.E. Coorkey Assay of intermediates of the citric acid cycle and related compounds by flourimetric enzymatic methods J.M. Lowenstein, Methods in Enzymology 1967 Academic Press New York 488 492
    • (1967) Methods in Enzymology , pp. 488-492
    • Williams, J.R.1    Coorkey, B.E.2
  • 35
    • 0022402287 scopus 로고
    • Swelling and contraction of the mitochondrial matrix. I. A structural interpretation of the relationship between light scattering and matrix volume
    • A.D. Beavis, R.D. Brannan, and K.D. Garlid Swelling and contraction of the mitochondrial matrix. I. A structural interpretation of the relationship between light scattering and matrix volume J. Biol. Chem. 260 1985 13424 13433
    • (1985) J. Biol. Chem. , vol.260 , pp. 13424-13433
    • Beavis, A.D.1    Brannan, R.D.2    Garlid, K.D.3
  • 37
    • 0023219256 scopus 로고
    • The deoxyribose method: A simple "test-tube" assay for determination of rate constants for reactions of hydroxyl radicals
    • B. Halliwell, J.M. Gutteridge, and O.I. Aruoma The deoxyribose method: a simple "test-tube" assay for determination of rate constants for reactions of hydroxyl radicals Anal. Biochem. 165 1987 215 219
    • (1987) Anal. Biochem. , vol.165 , pp. 215-219
    • Halliwell, B.1    Gutteridge, J.M.2    Aruoma, O.I.3
  • 38
    • 2442638714 scopus 로고    scopus 로고
    • Effect of Calotropis procera latex on isoproterenol induced myocardial infarction in albino rats
    • K. Mueen Ahmed, A. Rana, and V. Dixit Effect of Calotropis procera latex on isoproterenol induced myocardial infarction in albino rats Phytomedicine 11 2004 327 330
    • (2004) Phytomedicine , vol.11 , pp. 327-330
    • Mueen Ahmed, K.1    Rana, A.2    Dixit, V.3
  • 39
    • 78149467228 scopus 로고    scopus 로고
    • Caffeic acid protects rat heart mitochondria against isoproterenol-induced oxidative damage
    • K. Senthil Kumaran, and P. Stanely Mainzen Prince Caffeic acid protects rat heart mitochondria against isoproterenol-induced oxidative damage Cell Stress Chaperones 15 2010 791 806
    • (2010) Cell Stress Chaperones , vol.15 , pp. 791-806
    • Senthil Kumaran, K.1    Stanely Mainzen Prince, P.2
  • 40
    • 84855559900 scopus 로고    scopus 로고
    • Ellagic acid protects mitochondria from β-adrenergic agonist induced myocardial damage in rats; Evidence from in vivo, in vitro and ultra structural study
    • M. Mari Kannan, and S.D. Quine Ellagic acid protects mitochondria from β-adrenergic agonist induced myocardial damage in rats; evidence from in vivo, in vitro and ultra structural study Food Res. Int. 45 2012 1 8
    • (2012) Food Res. Int. , vol.45 , pp. 1-8
    • Mari Kannan, M.1    Quine, S.D.2
  • 41
    • 84870253172 scopus 로고    scopus 로고
    • An in vivo and in vitro study on the protective effects of N-acetylcysteine on mitochondrial dysfunction in isoproterenol treated myocardial infarcted rats
    • R.H. Basha, and D.H. Priscilla An in vivo and in vitro study on the protective effects of N-acetylcysteine on mitochondrial dysfunction in isoproterenol treated myocardial infarcted rats Exp. Toxic. Pathol. 65 2011 7 14
    • (2011) Exp. Toxic. Pathol. , vol.65 , pp. 7-14
    • Basha, R.H.1    Priscilla, D.H.2
  • 42
    • 0023811053 scopus 로고
    • Normal oxidative damage to mitochondrial and nuclear DNA is extensive
    • C. Richter, J.W. Park, and B.N. Ames Normal oxidative damage to mitochondrial and nuclear DNA is extensive Proc. Natl. Acad. Sci. U. S. A. 85 1988 6465 6467
    • (1988) Proc. Natl. Acad. Sci. U. S. A. , vol.85 , pp. 6465-6467
    • Richter, C.1    Park, J.W.2    Ames, B.N.3
  • 43
    • 1542397850 scopus 로고    scopus 로고
    • Biochemical changes on the cardioprotective effect of nicorandil and amlodipine during experimental myocardial infarction in rats
    • V. Sathish, K.K. Ebenezar, and T. Devaki Biochemical changes on the cardioprotective effect of nicorandil and amlodipine during experimental myocardial infarction in rats Pharmacol. Res. 48 2003 565 570
    • (2003) Pharmacol. Res. , vol.48 , pp. 565-570
    • Sathish, V.1    Ebenezar, K.K.2    Devaki, T.3
  • 44
    • 0021107546 scopus 로고
    • The subcellular location of isozymes of NADP-isocitrate dehydrogenase in tissues from pig, ox and rat
    • W.E. Plaut, M. Cook, and T. Aogaichi The subcellular location of isozymes of NADP-isocitrate dehydrogenase in tissues from pig, ox and rat Biochim. Biophys. Acta 760 1983 300 308
    • (1983) Biochim. Biophys. Acta , vol.760 , pp. 300-308
    • Plaut, W.E.1    Cook, M.2    Aogaichi, T.3
  • 45
    • 33749990899 scopus 로고    scopus 로고
    • Ferulic acid with ascorbic acid synergistically extenuates the mitochondrial dysfunction during beta-adrenergic catecholamine induced cardio toxicity in rats
    • S.K. Yogeeta, H.R. Raghavendran, A. Gnanapragasam, R. Subhashini, and T. Devaki Ferulic acid with ascorbic acid synergistically extenuates the mitochondrial dysfunction during beta-adrenergic catecholamine induced cardio toxicity in rats Chem. Biol. Interact. 163 2006 160 169
    • (2006) Chem. Biol. Interact. , vol.163 , pp. 160-169
    • Yogeeta, S.K.1    Raghavendran, H.R.2    Gnanapragasam, A.3    Subhashini, R.4    Devaki, T.5
  • 46
    • 34548363578 scopus 로고    scopus 로고
    • Effect of T. chebula on mitochondrial alterations in experimental myocardial injury
    • S. Suchalatha, P. Srinivasan, and C.S. Shyamala Devi Effect of T. chebula on mitochondrial alterations in experimental myocardial injury Chem. Biol. Interact. 169 2007 145 153
    • (2007) Chem. Biol. Interact. , vol.169 , pp. 145-153
    • Suchalatha, S.1    Srinivasan, P.2    Shyamala Devi, C.S.3
  • 47
    • 84929953851 scopus 로고    scopus 로고
    • Mitochondrial calcium uniporter protein MCU is involved in oxidative stress induced cell death
    • Y. Liao, Y. Hao, H. Chen, Q. He, Z. Yuan, and J. Cheng Mitochondrial calcium uniporter protein MCU is involved in oxidative stress induced cell death Protein Cell 6 2015 434 442
    • (2015) Protein Cell , vol.6 , pp. 434-442
    • Liao, Y.1    Hao, Y.2    Chen, H.3    He, Q.4    Yuan, Z.5    Cheng, J.6
  • 48
    • 0036788941 scopus 로고    scopus 로고
    • Regulation of hydrogen peroxide production by brain mitochondria by calcium and Bax
    • A.A. Starkov, B.M. Polster, and G. Fiskum Regulation of hydrogen peroxide production by brain mitochondria by calcium and Bax J. Neurochem. 83 2002 220 228
    • (2002) J. Neurochem. , vol.83 , pp. 220-228
    • Starkov, A.A.1    Polster, B.M.2    Fiskum, G.3
  • 49
    • 79955391768 scopus 로고    scopus 로고
    • Mitochondrial adaptations to physiological vs pathological cardiac hypertrophy
    • E.D. Abel1, and T. Doenst Mitochondrial adaptations to physiological vs pathological cardiac hypertrophy Cardiovasc. Res. 90 2011 234 242
    • (2011) Cardiovasc. Res. , vol.90 , pp. 234-242
    • Abel, E.D.1    Doenst, T.2
  • 50
    • 77951878150 scopus 로고    scopus 로고
    • Cardioprotective and antiapoptotic effects of heme oxygenase-1 in the failing heart
    • G. Wang, T. Hamid, R.J. Keith, G. Zhou, and C.R. Partridge Cardioprotective and antiapoptotic effects of heme oxygenase-1 in the failing heart Circulation 121 2010 1912 1925
    • (2010) Circulation , vol.121 , pp. 1912-1925
    • Wang, G.1    Hamid, T.2    Keith, R.J.3    Zhou, G.4    Partridge, C.R.5
  • 51
    • 80455176898 scopus 로고    scopus 로고
    • A biochemical, electrocardiographic, electrophoretic, histopathological and in vitro study on the protective effects of (-)epicatechin in isoproterenol-induced myocardial infarcted rats
    • P.S.M. Prince A biochemical, electrocardiographic, electrophoretic, histopathological and in vitro study on the protective effects of (-)epicatechin in isoproterenol-induced myocardial infarcted rats Eur. J. Pharmacol. 671 2011 95 101
    • (2011) Eur. J. Pharmacol. , vol.671 , pp. 95-101
    • Prince, P.S.M.1
  • 52
    • 0035162008 scopus 로고    scopus 로고
    • Ageing and the free radical theory
    • A.P. Wickens Ageing and the free radical theory Respir. Physiol. 128 2001 379 391
    • (2001) Respir. Physiol. , vol.128 , pp. 379-391
    • Wickens, A.P.1
  • 53
    • 68649096335 scopus 로고    scopus 로고
    • Antioxidant activities of major thyme ingredients and lack of (oxidative) DNA damage in V79 Chinese hamster lung fibroblast cells at low levels of carvacrol and thymol
    • U. Undeger, A. Basaran, G.H. Degen, and N. Basaran Antioxidant activities of major thyme ingredients and lack of (oxidative) DNA damage in V79 Chinese hamster lung fibroblast cells at low levels of carvacrol and thymol Food Chem. Toxicol. 47 2009 2037 2043
    • (2009) Food Chem. Toxicol. , vol.47 , pp. 2037-2043
    • Undeger, U.1    Basaran, A.2    Degen, G.H.3    Basaran, N.4
  • 54
    • 0034120730 scopus 로고    scopus 로고
    • The effect of thymol and its derivatives on reactions generating reactive oxygen species
    • I. Kruk, T. Michalska, K. Lichszteld, A. Koadna, and H.Y. Aboul-Enein The effect of thymol and its derivatives on reactions generating reactive oxygen species Chemosphere 41 2000 1059 1064
    • (2000) Chemosphere , vol.41 , pp. 1059-1064
    • Kruk, I.1    Michalska, T.2    Lichszteld, K.3    Koadna, A.4    Aboul-Enein, H.Y.5
  • 55
    • 84876930966 scopus 로고    scopus 로고
    • Carvacrol protects against acute myocardial infarction of rats via anti-oxidative and anti-apoptotic pathways
    • W. Yu, Q. Liu, and S. Zhu Carvacrol protects against acute myocardial infarction of rats via anti-oxidative and anti-apoptotic pathways Biol. Pharm. Bull. 36 2013 579 584
    • (2013) Biol. Pharm. Bull. , vol.36 , pp. 579-584
    • Yu, W.1    Liu, Q.2    Zhu, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.