Activation of cardiac muscarinic M 3 receptors induces delayed cardioprotection by preserving phosphorylated connexin43 and up-regulating cyclooxygenase-2 expression

British Journal of Pharmacology

Volumn 159, Issue 6, 2010, Pages 1217-1225

  Zhao, Jinlong ^a,b   Su, Yue ^a   Zhang, Yong ^a   Pan, Zhenwei ^a   Yang, Lili ^a   Chen, Xichuang ^a   Liu, Yan ^a   Lu, Yanjie ^a   Du, Zhimin ^a,b   Yang, Baofeng ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b Key Laboratory of Chemical Engineering Process and Technology for High efficiency Conversion College of Heilongjiang Province   (China)

Author keywords

Arrhythmia; COX 2; Cx43; Delayed preconditioning; Hsp70; Infarction; iNOS; M 3 mAChRs

Indexed keywords

4 DIPHENYLACETOXY 1 METHYLPIPERIDINE; CHOLINE; CONNEXIN 43; CYCLOOXYGENASE 2; HEAT SHOCK PROTEIN 70; INDUCIBLE NITRIC OXIDE SYNTHASE; METHOCTRAMINE; MUSCARINIC M3 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HEART ARRHYTHMIA; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; HEART VENTRICLE EXTRASYSTOLE; HEART VENTRICLE TACHYCARDIA; ISCHEMIC PRECONDITIONING; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; UPREGULATION;

ANIMALS; ARRHYTHMIAS, CARDIAC; CHOLINE; CONNEXIN 43; CYCLOOXYGENASE 2; DISEASE MODELS, ANIMAL; HEMODYNAMICS; MALE; MUSCARINIC AGONISTS; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; PHOSPHORYLATION; RATS; RATS, WISTAR; RECEPTOR, MUSCARINIC M3; TIME FACTORS; UP-REGULATION;

EID: 77949422497     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2009.00606.x     Document Type: Article

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