Isoproterenol instigates cardiomyocyte apoptosis and heart failure via AMPK inactivation-mediated endoplasmic reticulum stress

Apoptosis

Volumn 18, Issue 7, 2013, Pages 800-810

  Zhuo, Xiao Zhen ^a   Wu, Yue ^a,b   Ni, Ya Juan ^a   Liu, Jun Hui ^a   Gong, Min ^a   Wang, Xue Hui ^a   Wei, Feng ^a   Wang, Ting Zhong ^a   Yuan, Zuyi ^a   Ma, Ai Qun ^a   Song, Ping ^b  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

AMPK; Apoptosis; Endoplasmic reticulum stress; Heart failure; Isoproterenol

Indexed keywords

BRAIN NATRIURETIC PEPTIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; ISOPRENALINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; HEART FAILURE; HEART MUSCLE CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN SECRETION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; APOPTOSIS; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; HEART FAILURE; ISOPROTERENOL; MALE; METFORMIN; MICE; MICE, KNOCKOUT; MYOCARDIUM; MYOCYTES, CARDIAC; NATRIURETIC PEPTIDE, BRAIN; PHOSPHORYLATION; PYRAZOLES; PYRIMIDINES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

MUS; RATTUS;

EID: 84878702086     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-013-0843-5     Document Type: Article

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