Mitochondria-targeted peptide SS-31 attenuates renal injury via an antioxidant effect in diabetic nephropathy

American Journal of Physiology - Renal Physiology

Volumn 310, Issue 6, 2016, Pages F547-F559

  Hou, Yanjuan ^a   Li, Shuangcheng ^a   Wu, Ming ^a   Wei, Jinying ^a,b   Ren, Yunzhuo ^a,b   Du, Chunyang ^a,b   Wu, Haijiang ^a   Han, Caili ^a,b   Duan, Huijun ^a,b   Shi, Yonghong ^a,b  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b Key Laboratory of Hebei Neurology   (China)

Author keywords

Apoptosis; Diabetic nephropathy; Mitochondria; Oxidative stress; SS 31 peptide

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; COLLAGEN TYPE 4; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOCHROME C; ELAMIPRETIDE; FIBRONECTIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAX; PROTEIN BCL 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; STREPTOZOCIN; THIOREDOXIN 2; THIOREDOXIN INTERACTING PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; ARGINYL-2,'6'-DIMETHYLTYROSYL-LYSYL-PHENYLALANINAMIDE; CARRIER PROTEIN; CREB1 PROTEIN, MOUSE; GLUCOSE; NOX4 PROTEIN, MOUSE; OLIGOPEPTIDE; REACTIVE OXYGEN METABOLITE; TGFB1 PROTEIN, MOUSE; THIOREDOXIN; TXNIP PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KIDNEY HYPERTROPHY; KIDNEY INJURY; MESANGIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEINURIA; TREATMENT DURATION; UNINEPHRECTOMY; ANIMAL; CELL CULTURE; DIABETIC NEPHROPATHIES; DRUG EFFECTS; MALE; METABOLISM; MITOCHONDRION; PRECLINICAL STUDY;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARRIER PROTEINS; CELLS, CULTURED; COLLAGEN TYPE IV; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DIABETIC NEPHROPATHIES; DRUG EVALUATION, PRECLINICAL; FIBRONECTINS; GLUCOSE; MALE; MICE; MITOCHONDRIA; NADPH OXIDASE; OLIGOPEPTIDES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; THIOREDOXINS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84980370984     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00574.2014     Document Type: Article

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