Overexpression of MMP-7 increases collagen 1A2 in the aging kidney

Physiological Reports

Volumn 1, Issue 5, 2013, Pages

  Ślusarz, Anna ^a   Nichols, Lanita A ^a   Grunz Borgmann, Elizabeth A ^a   Chen, Gang ^b   Akintola, Adebayo D ^b   Catania, Jeffery M ^c   Burghardt, Robert C ^c   Trzeciakowski, Jerome P ^b   Parrish, Alan R ^a  

^a UNIVERSITY OF MISSOURI   (United States)

^b TEXAS A AND M UNIVERSITY SYSTEM   (United States)

^c TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Aging; Collagen; Fibrosis; MMP 7

Indexed keywords

COLLAGEN; COLLAGEN TYPE 1 A2; CYCLIC AMP DEPENDENT PROTEIN KINASE; ENZYME PRECURSOR; MATRILYSIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE P60; UNCLASSIFIED DRUG;

AGAR GEL ELECTROPHORESIS; AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALORIC RESTRICTION; CHEMOLUMINESCENCE; CHRONIC KIDNEY FAILURE; CONTROLLED STUDY; GENE OVEREXPRESSION; HIGH THROUGHPUT SEQUENCING; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY FIBROSIS; MALE; MOLECULAR CLONING; MRNA EXPRESSION ASSAY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; UPREGULATION; WESTERN BLOTTING;

EID: 84979880695     PISSN: None     EISSN: 2051817X     Source Type: Journal    
DOI: 10.1002/phy2.90     Document Type: Article

References (64)

1. Abramson, S. R., G. E. Conner, H. Nagase, I. Neuhaus, and J. F. Jr Woessner. 1995. Characterization of rat uterine matrilysin and its cDNA. Relationship to human pump-1 and activation of procollagenases. J. Biol. Chem. 270: 16016–16022.
2. Aggarwal, H. K., D. Jain, P. Talapatra, R. K. Yadav, T. Gupta, and K. L. Kathuria. 2010. Evaluation of role of doxycycline (a matrix metalloproteinase inhibitor) on renal functions in patients of diabetic nephropathy. Ren. Fail. 32: 941–946.
3. Ahuja, T. S. 2003. Doxycycline decreases proteinuria in glomerulonephritis. Am. J. Kidney Dis. 42: 376–380.
4. Akintola, A. D., Z. L. Crislip, J. M. Catania, G. Chen, W. E. Zimmer, R. C. Burghardt, et al. 2008. Promoter methylation is associated with the age-dependent loss of N-cadherin in the rat kidney. Am. J. Physiol. Renal Physiol. 294: F170–F176.
5. van Almen, G. C., W. Verhesen, R. E. van Leeuwen, M. van de Vrie, C. Eurlings, M. W. Schellings, et al. 2011. MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. Aging Cell 10: 769–779.
6. Baylis, C. 1994. Age-dependent glomerular damage in the rat. Dissociation between glomerular injury and both glomerular hypertension and hypertrophy. Male gender as a primary risk factor. J. Clin. Investig. 94: 1823–1829.
7. Baylis, C., and B. Corman. 1998. The aging kidney: insights from experimental studies. J. Am. Soc. Nephrol. 9: 699–709.
8. Bielesz, B., Y. Sirin, H. Si, T. Niranjan, A. Gruenwald, S. Ahn, et al. 2010. Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans. J. Clin. Investig. 120: 4040–4054.
9. Bohle, A., S. Mackensen-Haen, and H. von Gise. 1987. Significance of tubulointerstitial changes in the renal cortex for the excretory function and concentration ability of the kidney: a morphometric contribution. Am. J. Nephrol. 7: 421–433.
10. Boor, P., T. Ostendorf, and J. Floege. 2010. Renal fibrosis: novel insights into mechanisms and therapeutic targets. Nat. Rev. Nephrol. 6: 643–656.
11. von Bredow, D. C., A. E. Cress, E. W. Howard, G. T. Bowden, and R. B. Nagle. 1998. Activation of gelatinase-tissue-inhibitors-of-metalloproteinase complexes by matrilysin. Biochem. J. 331 (Pt 3): 965–972.
12. Catania, J. M., G. Chen, and A. R. Parrish. 2007. Role of matrix metalloproteinases in renal pathophysiologies. Am. J. Physiol. Renal Physiol. 292: F905–F911.
13. Chen, G., E. A. Bridenbaugh, A. D. Akintola, J. M. Catania, V. S. Vaidya, J. V. Bonventre, et al. 2007. Increased susceptibility of aging kidney to ischemic injury: identification of candidate genes changed during aging, but corrected by caloric restriction. Am. J. Physiol. Renal Physiol. 293: F1272–F1281.
14. Corman, B., and R. Owen. 1992. Normal development, growth, and aging of the kidney. Pp. 195–209 in U. Mohr, D. L. Dungworth and C. C. Capen, eds. Pathobiology of aging rats. DCILSI Press, Washington.
15. Correia, A. L., H. Mori, E. I. Chen, F. C. Schmitt, and M. J. Bissell. 2013. The hemopexin domain of MMP3 is responsible for mammary epithelial invasion and morphogenesis through extracellular interaction with HSP90beta. Genes Dev. 27: 805–817.
16. Fragiadaki, M., A. S. Witherden, T. Kaneko, S. Sonnylal, C. D. Pusey, G. Bou-Gharios, et al. 2011. Interstitial fibrosis is associated with increased COL1A2 transcription in AA-injured renal tubular epithelial cells in vivo. Matrix Biol. 30: 396–403.
17. Gaikwad, A. B., J. Gupta, and K. Tikoo. 2010. Epigenetic changes and alteration of Fbn1 and Col3A1 gene expression under hyperglycaemic and hyperinsulinaemic conditions. Biochem. J. 432: 333–341.
18. Gaire, M., Z. Magbanua, S. McDonnell, L. McNeil, D. H. Lovett, and L. M. Matrisian. 1994. Structure and expression of the human gene for the matrix metalloproteinase matrilysin. J. Biol. Chem. 269: 2032–2040.
19. Geiser, M., R. Cebe, D. Drewello, and R. Schmitz. 2001. Integration of PCR fragments at any specific site within cloning vectors without the use of restriction enzymes and DNA ligase. Biotechniques 31: 88–90, 92.
20. Ghosh, A. K., W. Yuan, Y. Mori, and J. Varga. 2000. Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators. Oncogene 19: 3546–3555.
21. Haley, D. P., and R. E. Bulger. 1983. The aging male rat: structure and function of the kidney. Am. J. Anat. 167: 1–13.
22. Hewitson, T. D. 2009. Renal tubulointerstitial fibrosis: common but never simple. Am. J. Physiol. Renal Physiol. 296: F1239–F1244.
23. Huang, C. C., J. H. Chuang, M. H. Chou, C. L. Wu, C. M. Chen, C. C. Wang, et al. 2005. Matrilysin (MMP-7) is a major matrix metalloproteinase upregulated in biliary atresia-associated liver fibrosis. Mod. Pathol. 18: 941–950.
24. Imai, K., Y. Yokohama, I. Nakanishi, E. Ohuchi, Y. Fujii, N. Nakai, et al. 1995. Matrix metalloproteinase 7 (matrilysin) from human rectal carcinoma cells. Activation of the precursor, interaction with other matrix metalloproteinases and enzymic properties. J. Biol. Chem. 270: 6691–6697.
25. Jovanovic, V., A. S. Dugast, J. M. Heslan, J. Ashton-Chess, M. Giral, N. Degauque, et al. 2008. Implication of matrix metalloproteinase 7 and the noncanonical wingless-type signaling pathway in a model of kidney allograft tolerance induced by the administration of antidonor class II antibodies. J. Immunol. 180: 1317–1325.
26. Kraft, P. J., D. E. Haynes-Johnson, L. Patel, J. A. Lenhart, R. A. Zivin, and S. S. Palmer. 2001. Fluorescence polarization assay and SDS-PAGE confirms matrilysin degrades fibronectin and collagen IV whereas gelatinase A degrades collagen IV but not fibronectin. Connect. Tissue Res. 42: 149–163.
27. Langmead, B., and S. L. Salzberg. 2012. Fast gapped-read alignment with Bowtie 2. Nat. Methods 9: 357–359.
28. Levey, A. S., and J. Coresh. 2012. Chronic kidney disease. Lancet 379: 165–180.
29. Lin, H. C., J. H. Chang, S. Jain, E. E. Gabison, T. Kure, T. Kato, et al. 2001. Matrilysin cleavage of corneal collagen type XVIII NC1 domain and generation of a 28-kDa fragment. Invest. Ophthalmol. Vis. Sci. 42: 2517–2524.
30. Massague, J., J. Seoane, and D. Wotton. 2005. Smad transcription factors. Genes Dev. 19: 2783–2810.
31. Melk, A., E. S. Mansfield, S. C. Hsieh, T. Hernandez-Boussard, P. Grimm, D. C. Rayner, et al. 2005. Transcriptional analysis of the molecular basis of human kidney aging using cDNA microarray profiling. Kidney Int. 68: 2667–2679.
32. Mimori, K., K. Yamashita, M. Ohta, K. Yoshinaga, K. Ishikawa, H. Ishii, et al. 2004. Coexpression of matrix metalloproteinase-7 (MMP-7) and epidermal growth factor (EGF) receptor in colorectal cancer: an EGF receptor tyrosine kinase inhibitor is effective against MMP-7-expressing cancer cells. Clin. Cancer Res. 10: 8243–8249.
33. Miyazaki, K., Y. Hattori, F. Umenishi, H. Yasumitsu, and M. Umeda. 1990. Purification and characterization of extracellular matrix-degrading metalloproteinase, matrin (pump-1), secreted from human rectal carcinoma cell line. Cancer Res. 50: 7758–7764.
34. Mori, H., A. T. Lo, J. L. Inman, J. Alcaraz, C. M. Ghajar, J. D. Mott, et al. 2013. Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin beta1. Development 140: 343–352.
35. Muller, D., B. Quantin, M. C. Gesnel, R. Millon-Collard, J. Abecassis, and R. Breathnach. 1988. The collagenase gene family in humans consists of at least four members. Biochem. J. 253: 187–192.
36. Musial, K., and D. Zwolinska. 2012. MMP-7 as a potential marker of cardiovascular complications in patients with chronic kidney disease (CKD). Basic Clin. Pharmacol. Toxicol. 111: 73–74.
37. Nagase, H., and J. F. Jr Woessner. 1999. Matrix metalloproteinases. J. Biol. Chem. 274: 21491–21494.
38. Quantin, B., G. Murphy, and R. Breathnach. 1989. Pump-1 cDNA codes for a protein with characteristics similar to those of classical collagenase family members. Biochemistry 28: 5327–5334.
39. Ramankulov, A., M. Lein, M. Johannsen, M. Schrader, K. Miller, and K. Jung. 2008. Plasma matrix metalloproteinase-7 as a metastatic marker and survival predictor in patients with renal cell carcinomas. Cancer Sci. 99: 1188–1194.
40. Ramirez, F., S. Tanaka, and G. Bou-Gharios. 2006. Transcriptional regulation of the human alpha2 (I) collagen gene (COL1A2), an informative model system to study fibrotic diseases. Matrix Biol. 25: 365–372.
41. Reckelhoff, J. F., and C. Baylis. 1992. Proximal tubular metalloprotease activity is decreased in the senescent rat kidney. Life Sci. 50: 959–963.
42. Reich, H. N., C. Landolt-Marticorena, P. C. Boutros, R. John, J. Wither, P. R. Fortin, et al. 2011. Molecular markers of injury in kidney biopsy specimens of patients with lupus nephritis. J. Mol. Diagn. 13: 143–151.
43. Rodder, S., A. Scherer, M. Korner, U. Eisenberger, A. Hertig, F. Raulf, et al. 2010. Meta-analyses qualify metzincins and related genes as acute rejection markers in renal transplant patients. Am. J. Transplant. 10: 286–297.
44. Rodwell, G. E., R. Sonu, J. M. Zahn, J. Lund, J. Wilhelmy, L. Wang, et al. 2004. A transcriptional profile of aging in the human kidney. PLoS Biol. 2: e427.
45. Romanic, A. M., C. L. Burns-Kurtis, Z. Ao, A. J. Arleth, and E. H. Ohlstein. 2001. Upregulated expression of human membrane type-5 matrix metalloproteinase in kidneys from diabetic patients. Am. J. Physiol. Renal Physiol. 281: F309–F317.
46. Rosas, I. O., T. J. Richards, K. Konishi, Y. Zhang, K. Gibson, A. E. Lokshin, et al. 2008. MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis. PLoS Med. 5: e93.
47. Sands, J. M. 2003. Urine-concentrating ability in the aging kidney. Sci. Aging Knowledge Environ. 2003: PE15.
48. Sasser, J. M., O. Akinsiku, N. C. Moningka, K. Jerzewski, C. Baylis, A. J. LeBlanc, et al. 2012. Sexual dimorphism in development of kidney damage in aging Fischer-344 rats. Gend. Med. 9: 219–231.
49. Schaefer, L., M. Teschner, H. Ling, U. Oldakowska, A. Heidland, and R. M. Schaefer. 1994. The aging rat kidney displays low glomerular and tubular proteinase activities. Am. J. Kidney Dis. 24: 499–504.
50. Stern, J. S., M. D. Gades, C. M. Wheeldon, and A. T. Borchers. 2001. Calorie restriction in obesity: prevention of kidney disease in rodents. J. Nutr. 131: 913S–917S.
51. Surendran, K., T. C. Simon, H. Liapis, and J. K. McGuire. 2004. Matrilysin (MMP-7) expression in renal tubular damage: association with Wnt4. Kidney Int. 65: 2212–2222.
52. Tan, X., H. Egami, M. Abe, F. Nozawa, M. Hirota, and M. Ogawa. 2005. Involvement of MMP-7 in invasion of pancreatic cancer cells through activation of the EGFR mediated MEK-ERK signal transduction pathway. J. Clin. Pathol. 58: 1242–1248.
53. Trapnell, C., A. Roberts, L. Goff, G. Pertea, D. Kim, D. R. Kelley, et al. 2012. Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks. Nat. Protoc. 7: 562–578.
54. Vandooren, J., P. E. Van den Steen, and G. Opdenakker. 2013. Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): the next decade. Crit. Rev. Biochem. Mol. Biol. 48: 222–272.
55. Varro, A., S. Kenny, E. Hemers, C. McCaig, S. Przemeck, T. C. Wang, et al. 2007. Increased gastric expression of MMP-7 in hypergastrinemia and significance for epithelial-mesenchymal signaling. Am. J. Physiol. Gastrointest. Liver Physiol. 292: G1133–G1140.
56. Witty, J. P., S. McDonnell, K. J. Newell, P. Cannon, M. Navre, R. J. Tressler, et al. 1994. Modulation of matrilysin levels in colon carcinoma cell lines affects tumorigenicity in vivo. Cancer Res. 54: 4805–4812.
57. Woessner, J. F. Jr, and C. J. Taplin. 1988. Purification and properties of a small latent matrix metalloproteinase of the rat uterus. J. Biol. Chem. 263: 16918–16925.
58. Wu, F., and S. Chakravarti. 2007. Differential expression of inflammatory and fibrogenic genes and their regulation by NF-kappaB inhibition in a mouse model of chronic colitis. J. Immunol. 179: 6988–7000.
59. Wynn, T. A. 2007. Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases. J. Clin. Investig. 117: 524–529.
60. Xue, M., and C. J. Jackson. 2008. Autocrine actions of matrix metalloproteinase (MMP)-2 counter the effects of MMP-9 to promote survival and prevent terminal differentiation of cultured human keratinocytes. J. Invest. Dermatol. 128: 2676–2685.
61. Zawada, E., F. K. Alvai, R. N. Santella, and D. Maddox. 1997. Influence of dietary macronutrients on glomerular senescence. Curr. Nephrol. 20: 1–47.
62. Zeisberg, M., and E. G. Neilson. 2010. Mechanisms of tubulointerstitial fibrosis. J. Am. Soc. Nephrol. 21: 1819–1834.
63. Zhang, W., J. Ou, Y. Inagaki, P. Greenwel, and F. Ramirez. 2000. Synergistic cooperation between Sp1 and Smad3/Smad4 mediates transforming growth factor beta1 stimulation of alpha 2 (I)-collagen (COL1A2) transcription. J. Biol. Chem. 275: 39237–39245.
64. Zuo, F., N. Kaminski, E. Eugui, J. Allard, Z. Yakhini, A. Ben-Dor, et al. 2002. Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans. Proc. Natl. Acad. Sci. USA 99: 6292–6297.