Interstitial fibrosis is associated with increased COL1A2 transcription in AA-injured renal tubular epithelial cells in vivo

Matrix Biology

Volumn 30, Issue 7-8, 2011, Pages 396-403

  Fragiadaki, Maria ^a   Witherden, Abigail S ^a   Kaneko, Tomoyo ^a   Sonnylal, Sonali ^b   Pusey, Charles D ^a   Bou Gharios, George ^c   Mason, Roger M ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b UNIVERSITY OF TEXAS   (United States)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

AAN; Aristolochic acid nephropathy; CCN2; COL1A2; Collagen transcription; Kidney fibrosis; Murine model of fibrosis; Renal tubular epithelial cells; Scarring

Indexed keywords

ARISTOLOCHIC ACID; BETA GALACTOSIDASE; COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; MESSENGER RNA; SCLEROPROTEIN; UVOMORULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; COL1A2 GENE; CONTROLLED STUDY; FEMALE; FIBROGENESIS; GENE; GENE ACTIVATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; IN VIVO STUDY; KIDNEY DISEASE; KIDNEY FIBROSIS; KIDNEY TUBULE CELL; LASER MICROSCOPY; MALE; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE;

ANIMALS; ARISTOLOCHIC ACIDS; BIOLOGICAL MARKERS; BLOOD UREA NITROGEN; CADHERINS; COLLAGEN TYPE I; CONNECTIVE TISSUE GROWTH FACTOR; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; EPITHELIAL CELLS; FEMALE; FIBROSIS; KIDNEY; KIDNEY TUBULES; LASER CAPTURE MICRODISSECTION; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PROMOTER REGIONS, GENETIC; TRANSCRIPTIONAL ACTIVATION; TRANSGENES;

MURINAE; MUS; MUS MUSCULUS;

EID: 80053909027     PISSN: 0945053X     EISSN: 15691802     Source Type: Journal    
DOI: 10.1016/j.matbio.2011.07.004     Document Type: Article

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