Microglia contribute to circuit defects in Mecp2 null mice independent of microglia-specific loss of Mecp2 expression

eLife

Volumn 5, Issue 2016JULY, 2016, Pages

  Schafer, Dorothy P ^a,b   Heller, Christopher T ^a,b   Gunner, Georgia ^a,b   Heller, Molly ^a   Gordon, Christopher ^a   Hammond, Timothy ^a   Wolf, Yochai ^c   Jung, Steffen ^c   Stevens, Beth ^a,d  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; METHYL CPG BINDING PROTEIN 2; MECP2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CONNECTOME; CONTROLLED STUDY; ELECTROPHYSIOLOGY; FEMALE; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LATERAL GENICULATE BODY; MALE; MICROGLIA; MORPHOLOGY; MOUSE; NEUROLOGICAL SCORE; NONHUMAN; PHENOTYPE; PRACTICE GUIDELINE; PROTEIN EXPRESSION; RETT SYNDROME; SCORING SYSTEM; VALIDATION PROCESS; ANIMAL; DEFICIENCY; DISEASE MODEL; ENDOCYTOSIS; KNOCKOUT MOUSE; METABOLISM; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SYNAPSE;

ANIMALS; DISEASE MODELS, ANIMAL; ENDOCYTOSIS; METHYL-CPG-BINDING PROTEIN 2; MICE; MICE, KNOCKOUT; MICROGLIA; NEURONS; RETT SYNDROME; SYNAPSES;

EID: 84979528624     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.15224     Document Type: Article

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