Carnosic acid nanoparticles suppress liver ischemia/reperfusion injury by inhibition of ROS, Caspases and NF-κB signaling pathway in mice

Biomedicine and Pharmacotherapy

Volumn 82, Issue , 2016, Pages 237-246

  Li, Hui ^a   Sun, Jian Jun ^a   Chen, Guo Yong ^a   Wang, Wei Wei ^a   Xie, Zhan Tao ^a   Tang, Gao Feng ^a   Wei, Si Dong ^a  

^a ZHENGZHOU UNIVERSITY   (China)

Author keywords

Apoptosis; Carnosic acid nanoparticles; Inflammation; Ischemia reperfusion injury; ROS

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARNOSIC ACID; CASPASE 3; CASPASE 9; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; NANOPARTICLE; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; ABIETANE DERIVATIVE; CASPASE; LIPOPOLYSACCHARIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; LIVER ISCHEMIA; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; REPERFUSION INJURY; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; CHEMISTRY; DRUG EFFECTS; HEPATIC STELLATE CELL; INFLAMMATION; LIVER; METABOLISM; PATHOLOGY; ULTRASTRUCTURE;

ANIMALS; APOPTOSIS; CASPASES; DITERPENES, ABIETANE; HEPATIC STELLATE CELLS; INFLAMMATION; LIPOPOLYSACCHARIDES; LIVER; MALE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; NANOPARTICLES; NF-KAPPA B; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

EID: 84979496897     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2016.04.064     Document Type: Article

References (35)

1. [1] Luo, C., Yuan, D., Li, X., Yao, W., Luo, G., Chi, X., Li, H., Irwin, M.G., Xia, Z., Hei, Z., Propofol attenuated acute kidney injury after orthotopic liver transplantation via inhibiting gap junction composed of connexin 32. Anesthesiology 122 (2015), 72–86.
2. [2] Ohkohchi, N., Mechanisms of preservation and ischemic/reperfusion injury in liver transplantation. Transplant. Proc. 34 (2002), 2670–2673.
3. [3] Sanada, Y., Mizuta, K., Urahashi, T., Ihara, Y., Wakiya, T., Okada, N., Yamada, N., Ushijima, K., Otomo, S., Sakamoto, K., et al. Impact of endotoxin measured by an endotoxin activity assay during liver transplantation. J. Surg. Res. 180 (2013), 349–355.
4. [4] Cheung, S., Tai, J., Anti-proliferative and antioxidant properties of rosemary Rosmarinus officinalis. Oncol. Rep. 17 (2007), 1525–1531.
5. [5] Steiner, M., Priel, I., Giat, J., Levy, J., Sharoni, Y., Danilenko, M., Carnosic acid inhibits proliferation and augments differentiation of human leukemic cells induced by 1,25-dihydroxyvitamin D3 and retinoic acid. Nutr. Cancer 41 (2001), 135–144.
6. [6] Yu, Y.M., Lin, C.H., Chan, H.C., Tsai, H.D., Carnosic acid reduces cytokine-induced adhesion molecules expression and monocyte adhesion to endothelial cells. Eur. J. Nutr. 48 (2009), 101–106.
7. [7] Yu, Y.M., Lin, H.C., Chang, W.C., Carnosic acid prevents the migration of human aortic smooth muscle cells by inhibiting the activation and expression of matrix metalloproteinase-9. Br. J. Nutr. 100 (2008), 731–738.
8. [8] Lou, X.W.D., Archer, L.A., Yang, Z., Hollow micro-/nanostructures: synthesis and applications. Adv. Mater. 20 (2008), 3987–4019.
9. [9] Yu, H.C., Bai, L., Yue, S.Q., et al. Notch signal protects non-parenchymal cells from ischemia/reperfusion injury in vitro by repressing ROS. Ann. Hepatol. 12 (2013), 815–821.
10. [10] Vaka, S.R., Shivakumar, H.N., Repka, M.A., Murthy, S.N., Formulation and evaluation of carnosic acid nanoparticulate system for upregulation of neurotrophins in the brain upon intranasal administration. J. Drug Target 21 (2013), 44–53.
11. [11] Mederacke, I., Dapito, D.H., AffòS, Uchinami H., High-yield and high-purity isolation of hepatic stellate cells from normal and fibrotic mouse livers. Nat. Protoc. 10 (2015), 305–315.
12. [12] Ninomiya, K., Matsuda, H., Shimoda, H., Nishida, N., Kasajima, N., et al. Carnosic acid,a new class of lipid absorption inhibitor from sage. Bioorg. Med. Chem. Lett. 14 (2004), 1943–1946.
13. [13] Wang, W., Wang, C., Ding, X.Q., Pan, Y., Gu, T.T., Wang, M.X., Liu, Y.L., et al. Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats. Br. J. Pharmacol. 169 (2013), 1352–1371.
14. [14] Jia, D., Duan, F., Peng, P., Sun, L., Liu, X., Wang, L., et al. Up-regulation of RACK1 by TGF-beta1 promotes hepatic fibrosis in mice. PLoS One, 8, 2013, e60115.
15. 4)-induced liver fibrosis by downregulating MAPK and NF-kappaB signaling pathways. FEBS Lett. 588 (2014), 2095–2100.
16. [16] Son, T.G., Camandola, S., Arumugam, T.V., et al. Plumbagin, a novel NrF2/ARE activator, protects against cerebral ischemia. J. Neurochem. 112 (2010), 1316–1326.
17. [17] Haddad, J.J., The role of Bax/Bcl-2 and pro-caspase peptides in hypoxia/reperfusion-dependent regulation of MAPK (ERK): discordant proteomic effect of MAPK (p38). Protein Pept. Lett. 14 (2007), 361–371.
18. [18] Zhao, L.D., Wang, J.H., Jin, G.R., Zhao, Y., Zhang, H.J., Neuroprotective effect of Buyang Huanwu decoction against focal cerebral ischemia/reperfusion injury in rats—time window and mechanism. J. Ethnopharmacol. 140 (2012), 339–344.
19. [19] Li, Y., Chen, Y., Zhang, J., Zhu, J.F., Liu, Z.J., Liang, S.Y., Sun, K., Liao, W.Y., Gong, J.P., Protective effect of glutamine-enriched early enteral nutrition on intestinal mucosal barrier injury after liver transplantation in rats. Am. J. Surg. 199 (2010), 35–42.
20. [20] Zhang, A., Chi, X., Luo, G., Hei, Z., Xia, H., Luo, C., Wang, Y., Mao, X., Xia, Z., Mast cell stabilization alleviates acute lung injury after orthotopic autologous liver transplantation in rats by down-regulating inflammation. PLoS One, 8, 2016, e752622013.
21. [21] Mosbah, I.B., Zaouali, M.A., Martel, C., Bjaoui, M., Abdennebi, H.B., Hotter, G., Brenner, C., Roselló-Catafau, J., IGL-1 solution reduces endoplasmic reticulum stress and apoptosis in rat liver transplantation. Cell Death Dis., 3, 2016, e2792012.
22. [22] Romano, C.S., Abadi, K., Repetto, V., Vojnov, A., Moreno, S., Synergistic antioxidant and antibacterial activity of rosemary plus butylated derivatives. Food Chem. 115 (2008), 456–461.
23. [23] Wang, M.E., Chen, Y.C., Chen, I.S., Hsieh, S.C., Chen, S.S., Chiu, C.H., Curcumin protects against thioacetamide-induced hepatic fibrosis by attenuating the inflammatory response and inducing apoptosis of damaged hepatocytes. J. Nutr. Biochem. 23 (2012), 1352–1366.
24. [24] Kamiike, W., Fujikawa, M., Koseki, M., Sumimura, J., Miyata, M., Kawashima, Y., et al. Different patterns of leakage of cytosolic and mitochondrial enzymes. Clin. Chim. Acta 185 (1989), 265–270.
25. [25] Parola, M., Robino, G., Oxidative stress-related molecules and liver fibrosis. J. Hepatol. 35 (2001), 297–306.
26. [26] Zhang, R., Kang, K.A., Piao, M.J., Ko, D.O., Wang, Z.H., Chang, W.Y., You, H.J., Lee, I.K., Kim, B.J., Kang, S.S., Hyun, J.W., Preventive effect of 7,8-dihydroxyflavone against oxidative stress-induced genotoxicity. Biol. Pharm. Bull. 32 (2009), 166–171.
27. [27] Li, M.H., Cha, Y.N., Surh, Y.J., Peroxynitrite induces HO-1 expression via PI3K/Akt-dependent activation of NF-E2-related factor 2 in PC12 cells. Free Radic. Biol. Med. 41 (2006), 1079–1091.
28. [28] Cullinan, S.B., Diehl, J.A., PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress. J. Biol. Chem. 279 (2004), 20108–20117.
29. [29] Stoltzman, C.A., Kaadige, M.R., Peterson, C.W., Ayer, D.E., MondoA senses non-glucose sugars: regulation of thioredoxin-interacting protein (TXNIP) and the hexose transport curb. J. Biol. Chem. 286 (2011), 38027–38034.
30. [30] Li, Q., Zhang, R., Guo, Y.L., Mei, Y.W., Effect of neuregulin on apoptosis and expressions of STAT3 and GFAP in rats following cerebral ischemic reperfusion. J. Mol. Neurosci. 37 (2009), 67–73.
31. [31] Shin, D.Y., Kim, G.Y., Lee, J.H., Choi, B.T., Yoo, Y.H., Choi, Y.H., Apoptosis induction of human prostate carcinoma DU145 cells by diallyl disulfide via modulation of JNK and PI3K/AKT signaling pathways. Int. J. Mol. Sci. 13 (2012), 14158–14171.
32. [32] Chandel, N.S., Trzyna, W.C., McClintock, D.S., Schumacker, P.T., Role of oxidants in NF-kappa B activation and TNF-alpha gene transcription induced by hypoxia and endotoxin. J. Immunol. 165 (2000), 1013–1021.
33. [33] Kamo, N., Ke, B., Ghaffari, A.A., Shen, X.D., Busuttil, R.W., Cheng, G., Kupiec-Weglinski, J.W., ASC/caspase-1/IL-1β signaling triggers inflammatory responses by promoting HMGB1 induction in liver ischemia/reperfusion injury. Hepatology 58 (2013), 351–362.
34. [34] Xiong, H.Q., Abbruzzese, J.L., Lin, E., Wang, L., Zheng, L., Xie, K., NF-kappaB activity blockade impairs the angiogenic potential of human pancreatic cancer cells. Int. J. Cancer 108 (2004), 181–188.
35. [35] Maeda, S., Yoshida, H., Ogura, K., et al. H. Pylori activates NF-kappaB through a signaling pathway involving IkappaB kinases, NF-kappaB-inducing kinase, TRAF2 and TRAF6 in gastric cancer cells. Gastroenterology 119 (2000), 97–108.